| Full name: oxoglutarate dehydrogenase like | Alias Symbol: FLJ10851 | ||
| Type: protein-coding gene | Cytoband: 10q11.23 | ||
| Entrez ID: 55753 | HGNC ID: HGNC:25590 | Ensembl Gene: ENSG00000197444 | OMIM ID: 617513 |
| Drug and gene relationship at DGIdb | |||
Expression of OGDHL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OGDHL | 55753 | 219277_s_at | 0.6287 | 0.0801 | |
| GSE20347 | OGDHL | 55753 | 219277_s_at | 0.5445 | 0.0010 | |
| GSE23400 | OGDHL | 55753 | 219277_s_at | 0.0492 | 0.5447 | |
| GSE26886 | OGDHL | 55753 | 219277_s_at | 0.8596 | 0.0000 | |
| GSE29001 | OGDHL | 55753 | 219277_s_at | 0.6138 | 0.0146 | |
| GSE38129 | OGDHL | 55753 | 219277_s_at | 0.6826 | 0.0007 | |
| GSE45670 | OGDHL | 55753 | 219277_s_at | 0.6872 | 0.0166 | |
| GSE53622 | OGDHL | 55753 | 2523 | 0.7203 | 0.0088 | |
| GSE53624 | OGDHL | 55753 | 2523 | 1.8174 | 0.0000 | |
| GSE63941 | OGDHL | 55753 | 219277_s_at | 1.1526 | 0.1458 | |
| GSE77861 | OGDHL | 55753 | 219277_s_at | 0.0807 | 0.5931 | |
| SRP159526 | OGDHL | 55753 | RNAseq | 3.7052 | 0.0000 | |
| TCGA | OGDHL | 55753 | RNAseq | 0.4449 | 0.3572 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by OGDHL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OGDHL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OGDHL | 55753 | 2 | 5 | 23 | |
| GSE20123 | OGDHL | 55753 | 2 | 5 | 23 | |
| GSE43470 | OGDHL | 55753 | 2 | 6 | 35 | |
| GSE46452 | OGDHL | 55753 | 0 | 13 | 46 | |
| GSE47630 | OGDHL | 55753 | 4 | 12 | 24 | |
| GSE54993 | OGDHL | 55753 | 9 | 0 | 61 | |
| GSE54994 | OGDHL | 55753 | 2 | 10 | 41 | |
| GSE60625 | OGDHL | 55753 | 0 | 0 | 11 | |
| GSE74703 | OGDHL | 55753 | 2 | 3 | 31 | |
| GSE74704 | OGDHL | 55753 | 1 | 4 | 15 | |
| TCGA | OGDHL | 55753 | 12 | 22 | 62 |
Total number of gains: 36; Total number of losses: 80; Total Number of normals: 372.
Somatic mutations of OGDHL:
Generating mutation plots.
Highly correlated genes for OGDHL:
Showing top 20/318 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OGDHL | SLC22A4 | 0.707207 | 3 | 0 | 3 |
| OGDHL | STRADA | 0.692442 | 3 | 0 | 3 |
| OGDHL | MRPL36 | 0.691099 | 3 | 0 | 3 |
| OGDHL | CALB1 | 0.68437 | 3 | 0 | 3 |
| OGDHL | SFXN1 | 0.672115 | 4 | 0 | 3 |
| OGDHL | TMEM45A | 0.670963 | 3 | 0 | 3 |
| OGDHL | EME1 | 0.662682 | 3 | 0 | 3 |
| OGDHL | GPR150 | 0.646709 | 3 | 0 | 3 |
| OGDHL | TNFRSF18 | 0.645686 | 3 | 0 | 3 |
| OGDHL | NPW | 0.640953 | 4 | 0 | 3 |
| OGDHL | ZNF469 | 0.634803 | 4 | 0 | 3 |
| OGDHL | AP3D1 | 0.629591 | 3 | 0 | 3 |
| OGDHL | RGS19 | 0.629333 | 4 | 0 | 3 |
| OGDHL | PLEKHG4B | 0.62903 | 6 | 0 | 4 |
| OGDHL | EPHB4 | 0.618026 | 5 | 0 | 3 |
| OGDHL | MRPL28 | 0.617606 | 5 | 0 | 4 |
| OGDHL | PLAU | 0.616322 | 4 | 0 | 3 |
| OGDHL | FANCA | 0.610575 | 5 | 0 | 5 |
| OGDHL | JAKMIP2 | 0.609709 | 4 | 0 | 4 |
| OGDHL | HOXC9 | 0.606627 | 3 | 0 | 3 |
For details and further investigation, click here
