| Full name: tet methylcytosine dioxygenase 3 | Alias Symbol: MGC22014|hCG_40738 | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 200424 | HGNC ID: HGNC:28313 | Ensembl Gene: ENSG00000187605 | OMIM ID: 613555 |
| Drug and gene relationship at DGIdb | |||
Expression of TET3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TET3 | 200424 | 235542_at | 0.8235 | 0.3230 | |
| GSE20347 | TET3 | 200424 | 214754_at | 0.0877 | 0.4056 | |
| GSE23400 | TET3 | 200424 | 214754_at | 0.0273 | 0.5991 | |
| GSE26886 | TET3 | 200424 | 235542_at | -0.1532 | 0.5069 | |
| GSE29001 | TET3 | 200424 | 214754_at | -0.0591 | 0.6547 | |
| GSE38129 | TET3 | 200424 | 214754_at | 0.1152 | 0.3043 | |
| GSE45670 | TET3 | 200424 | 235542_at | 0.2624 | 0.1969 | |
| GSE53622 | TET3 | 200424 | 20888 | 0.3197 | 0.1097 | |
| GSE53624 | TET3 | 200424 | 20888 | -0.0199 | 0.9324 | |
| GSE63941 | TET3 | 200424 | 235542_at | 1.0690 | 0.1193 | |
| GSE77861 | TET3 | 200424 | 235542_at | 0.4670 | 0.0947 | |
| GSE97050 | TET3 | 200424 | A_33_P3331335 | -0.0023 | 0.9948 | |
| SRP007169 | TET3 | 200424 | RNAseq | 0.6338 | 0.1304 | |
| SRP008496 | TET3 | 200424 | RNAseq | 0.6102 | 0.0265 | |
| SRP064894 | TET3 | 200424 | RNAseq | -0.4286 | 0.1797 | |
| SRP133303 | TET3 | 200424 | RNAseq | 0.2214 | 0.3311 | |
| SRP159526 | TET3 | 200424 | RNAseq | 0.5507 | 0.0121 | |
| SRP193095 | TET3 | 200424 | RNAseq | 0.1548 | 0.1974 | |
| SRP219564 | TET3 | 200424 | RNAseq | -0.0354 | 0.9585 | |
| TCGA | TET3 | 200424 | RNAseq | 0.2681 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TET3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TET3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TET3 | 200424 | 10 | 1 | 19 | |
| GSE20123 | TET3 | 200424 | 10 | 1 | 19 | |
| GSE43470 | TET3 | 200424 | 4 | 0 | 39 | |
| GSE46452 | TET3 | 200424 | 2 | 3 | 54 | |
| GSE47630 | TET3 | 200424 | 7 | 0 | 33 | |
| GSE54993 | TET3 | 200424 | 0 | 6 | 64 | |
| GSE54994 | TET3 | 200424 | 10 | 0 | 43 | |
| GSE60625 | TET3 | 200424 | 0 | 3 | 8 | |
| GSE74703 | TET3 | 200424 | 4 | 0 | 32 | |
| GSE74704 | TET3 | 200424 | 8 | 0 | 12 | |
| TCGA | TET3 | 200424 | 38 | 2 | 56 |
Total number of gains: 93; Total number of losses: 16; Total Number of normals: 379.
Somatic mutations of TET3:
Generating mutation plots.
Highly correlated genes for TET3:
Showing top 20/144 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TET3 | LINC00299 | 0.698318 | 3 | 0 | 3 |
| TET3 | OTUB2 | 0.688152 | 3 | 0 | 3 |
| TET3 | CCDC33 | 0.681831 | 3 | 0 | 3 |
| TET3 | TNK2 | 0.679421 | 3 | 0 | 3 |
| TET3 | POLQ | 0.66844 | 5 | 0 | 5 |
| TET3 | CFL1 | 0.664875 | 3 | 0 | 3 |
| TET3 | CRYAA | 0.664777 | 3 | 0 | 3 |
| TET3 | PAFAH1B3 | 0.655499 | 3 | 0 | 3 |
| TET3 | POM121 | 0.65122 | 4 | 0 | 3 |
| TET3 | NUDT22 | 0.648379 | 3 | 0 | 3 |
| TET3 | GRK6 | 0.638206 | 3 | 0 | 3 |
| TET3 | GPR180 | 0.634263 | 3 | 0 | 3 |
| TET3 | SFXN1 | 0.633308 | 6 | 0 | 5 |
| TET3 | CBX8 | 0.633292 | 5 | 0 | 4 |
| TET3 | GEMIN2 | 0.630388 | 3 | 0 | 3 |
| TET3 | ALAS2 | 0.628016 | 3 | 0 | 3 |
| TET3 | TFAP2C | 0.624667 | 6 | 0 | 6 |
| TET3 | LRFN1 | 0.624252 | 3 | 0 | 3 |
| TET3 | TMEM184A | 0.616393 | 3 | 0 | 3 |
| TET3 | TNR | 0.615926 | 3 | 0 | 3 |
For details and further investigation, click here
