| Full name: death domain containing 1 | Alias Symbol: FLJ16686 | ||
| Type: protein-coding gene | Cytoband: 4p14 | ||
| Entrez ID: 401124 | HGNC ID: HGNC:37261 | Ensembl Gene: ENSG00000197057 | OMIM ID: 616979 |
| Drug and gene relationship at DGIdb | |||
Expression of DTHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DTHD1 | 401124 | 1564160_at | 0.0820 | 0.7643 | |
| GSE26886 | DTHD1 | 401124 | 1564160_at | 0.0740 | 0.4160 | |
| GSE45670 | DTHD1 | 401124 | 1564160_at | 0.0016 | 0.9856 | |
| GSE53622 | DTHD1 | 401124 | 38153 | -0.8574 | 0.0010 | |
| GSE53624 | DTHD1 | 401124 | 38153 | -0.7256 | 0.0000 | |
| GSE63941 | DTHD1 | 401124 | 1564160_at | 0.0195 | 0.8601 | |
| GSE77861 | DTHD1 | 401124 | 1564160_at | -0.0664 | 0.3757 | |
| SRP133303 | DTHD1 | 401124 | RNAseq | -0.4715 | 0.2390 | |
| SRP159526 | DTHD1 | 401124 | RNAseq | -0.6851 | 0.5018 | |
| TCGA | DTHD1 | 401124 | RNAseq | 0.5235 | 0.3511 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DTHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DTHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DTHD1 | 401124 | 0 | 18 | 12 | |
| GSE20123 | DTHD1 | 401124 | 0 | 17 | 13 | |
| GSE43470 | DTHD1 | 401124 | 0 | 14 | 29 | |
| GSE46452 | DTHD1 | 401124 | 1 | 37 | 21 | |
| GSE47630 | DTHD1 | 401124 | 1 | 19 | 20 | |
| GSE54993 | DTHD1 | 401124 | 8 | 0 | 62 | |
| GSE54994 | DTHD1 | 401124 | 4 | 10 | 39 | |
| GSE60625 | DTHD1 | 401124 | 0 | 0 | 11 | |
| GSE74703 | DTHD1 | 401124 | 0 | 12 | 24 | |
| GSE74704 | DTHD1 | 401124 | 0 | 11 | 9 | |
| TCGA | DTHD1 | 401124 | 10 | 47 | 39 |
Total number of gains: 24; Total number of losses: 185; Total Number of normals: 279.
Somatic mutations of DTHD1:
Generating mutation plots.
Highly correlated genes for DTHD1:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DTHD1 | TRAT1 | 0.718977 | 3 | 0 | 3 |
| DTHD1 | CD3E | 0.689866 | 3 | 0 | 3 |
| DTHD1 | CD247 | 0.685033 | 4 | 0 | 4 |
| DTHD1 | TMEM156 | 0.676984 | 3 | 0 | 3 |
| DTHD1 | ZAP70 | 0.666308 | 3 | 0 | 3 |
| DTHD1 | SAMD3 | 0.664908 | 4 | 0 | 4 |
| DTHD1 | NCKAP1L | 0.663464 | 4 | 0 | 4 |
| DTHD1 | IKZF1 | 0.658076 | 3 | 0 | 3 |
| DTHD1 | SH2D1A | 0.653535 | 4 | 0 | 3 |
| DTHD1 | PARP15 | 0.650488 | 4 | 0 | 3 |
| DTHD1 | CD79B | 0.64387 | 4 | 0 | 4 |
| DTHD1 | APBB1IP | 0.63913 | 3 | 0 | 3 |
| DTHD1 | ACAP1 | 0.632871 | 4 | 0 | 3 |
| DTHD1 | CD40LG | 0.624096 | 4 | 0 | 4 |
| DTHD1 | CD96 | 0.617469 | 4 | 0 | 3 |
| DTHD1 | BIN2 | 0.617057 | 3 | 0 | 3 |
| DTHD1 | CD52 | 0.616147 | 4 | 0 | 4 |
| DTHD1 | GAB3 | 0.615639 | 3 | 0 | 3 |
| DTHD1 | DOCK2 | 0.609941 | 4 | 0 | 4 |
| DTHD1 | CD74 | 0.603028 | 4 | 0 | 4 |
For details and further investigation, click here
