| Full name: sialic acid binding Ig like lectin 9 | Alias Symbol: CD329 | ||
| Type: protein-coding gene | Cytoband: 19q13.3-q13.4 | ||
| Entrez ID: 27180 | HGNC ID: HGNC:10878 | Ensembl Gene: ENSG00000129450 | OMIM ID: 605640 |
| Drug and gene relationship at DGIdb | |||
Expression of SIGLEC9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SIGLEC9 | 27180 | 210569_s_at | 0.1288 | 0.7450 | |
| GSE20347 | SIGLEC9 | 27180 | 210569_s_at | 0.0983 | 0.2583 | |
| GSE23400 | SIGLEC9 | 27180 | 210569_s_at | -0.0916 | 0.0117 | |
| GSE26886 | SIGLEC9 | 27180 | 210569_s_at | 0.1618 | 0.2058 | |
| GSE29001 | SIGLEC9 | 27180 | 210569_s_at | 0.0721 | 0.6491 | |
| GSE38129 | SIGLEC9 | 27180 | 210569_s_at | 0.0144 | 0.8700 | |
| GSE45670 | SIGLEC9 | 27180 | 210569_s_at | 0.2008 | 0.0213 | |
| GSE53622 | SIGLEC9 | 27180 | 73031 | 0.2612 | 0.0667 | |
| GSE53624 | SIGLEC9 | 27180 | 73031 | 0.7211 | 0.0000 | |
| GSE63941 | SIGLEC9 | 27180 | 210569_s_at | 0.0593 | 0.7056 | |
| GSE77861 | SIGLEC9 | 27180 | 210569_s_at | 0.0210 | 0.9086 | |
| GSE97050 | SIGLEC9 | 27180 | A_24_P125561 | 0.1902 | 0.5167 | |
| SRP064894 | SIGLEC9 | 27180 | RNAseq | 1.5762 | 0.0000 | |
| SRP133303 | SIGLEC9 | 27180 | RNAseq | 0.5183 | 0.0097 | |
| SRP159526 | SIGLEC9 | 27180 | RNAseq | 0.9882 | 0.1187 | |
| SRP193095 | SIGLEC9 | 27180 | RNAseq | 0.8810 | 0.0000 | |
| SRP219564 | SIGLEC9 | 27180 | RNAseq | 0.9345 | 0.0695 | |
| TCGA | SIGLEC9 | 27180 | RNAseq | 0.7378 | 0.0058 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SIGLEC9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SIGLEC9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SIGLEC9 | 27180 | 3 | 4 | 23 | |
| GSE20123 | SIGLEC9 | 27180 | 3 | 3 | 24 | |
| GSE43470 | SIGLEC9 | 27180 | 4 | 11 | 28 | |
| GSE46452 | SIGLEC9 | 27180 | 45 | 1 | 13 | |
| GSE47630 | SIGLEC9 | 27180 | 9 | 6 | 25 | |
| GSE54993 | SIGLEC9 | 27180 | 17 | 4 | 49 | |
| GSE54994 | SIGLEC9 | 27180 | 4 | 14 | 35 | |
| GSE60625 | SIGLEC9 | 27180 | 9 | 0 | 2 | |
| GSE74703 | SIGLEC9 | 27180 | 4 | 7 | 25 | |
| GSE74704 | SIGLEC9 | 27180 | 3 | 1 | 16 | |
| TCGA | SIGLEC9 | 27180 | 14 | 19 | 63 |
Total number of gains: 115; Total number of losses: 70; Total Number of normals: 303.
Somatic mutations of SIGLEC9:
Generating mutation plots.
Highly correlated genes for SIGLEC9:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SIGLEC9 | CFC1 | 0.711243 | 3 | 0 | 3 |
| SIGLEC9 | LINC00642 | 0.699938 | 3 | 0 | 3 |
| SIGLEC9 | RHAG | 0.686166 | 3 | 0 | 3 |
| SIGLEC9 | NTNG2 | 0.685843 | 3 | 0 | 3 |
| SIGLEC9 | TMUB1 | 0.676131 | 4 | 0 | 4 |
| SIGLEC9 | OSBPL5 | 0.669428 | 3 | 0 | 3 |
| SIGLEC9 | MYO1G | 0.661906 | 3 | 0 | 3 |
| SIGLEC9 | ANAPC2 | 0.653818 | 3 | 0 | 3 |
| SIGLEC9 | TBC1D10C | 0.652893 | 3 | 0 | 3 |
| SIGLEC9 | NSMF | 0.65181 | 3 | 0 | 3 |
| SIGLEC9 | HLX | 0.649408 | 4 | 0 | 4 |
| SIGLEC9 | PHF21A | 0.648609 | 4 | 0 | 4 |
| SIGLEC9 | WNT10B | 0.633716 | 3 | 0 | 3 |
| SIGLEC9 | ZNF646 | 0.628191 | 4 | 0 | 3 |
| SIGLEC9 | KCNQ1DN | 0.627412 | 4 | 0 | 3 |
| SIGLEC9 | NKAIN1 | 0.621323 | 3 | 0 | 3 |
| SIGLEC9 | ODF3B | 0.619875 | 4 | 0 | 3 |
| SIGLEC9 | CYP17A1 | 0.619686 | 4 | 0 | 3 |
| SIGLEC9 | LIME1 | 0.6189 | 4 | 0 | 3 |
| SIGLEC9 | FMNL1 | 0.615334 | 7 | 0 | 6 |
For details and further investigation, click here
