| Full name: H2.0 like homeobox | Alias Symbol: HB24 | ||
| Type: protein-coding gene | Cytoband: 1q41 | ||
| Entrez ID: 3142 | HGNC ID: HGNC:4978 | Ensembl Gene: ENSG00000136630 | OMIM ID: 142995 |
| Drug and gene relationship at DGIdb | |||
Expression of HLX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HLX | 3142 | 214438_at | 0.2886 | 0.3398 | |
| GSE20347 | HLX | 3142 | 214438_at | 0.2259 | 0.0074 | |
| GSE23400 | HLX | 3142 | 214438_at | 0.1189 | 0.0016 | |
| GSE26886 | HLX | 3142 | 214438_at | 0.6033 | 0.0012 | |
| GSE29001 | HLX | 3142 | 214438_at | 0.5098 | 0.0979 | |
| GSE38129 | HLX | 3142 | 214438_at | 0.1155 | 0.4881 | |
| GSE45670 | HLX | 3142 | 214438_at | -0.1325 | 0.6291 | |
| GSE53622 | HLX | 3142 | 86638 | 0.4133 | 0.0001 | |
| GSE53624 | HLX | 3142 | 86638 | 0.7812 | 0.0000 | |
| GSE63941 | HLX | 3142 | 214438_at | -1.2980 | 0.0009 | |
| GSE77861 | HLX | 3142 | 214438_at | 0.0273 | 0.8656 | |
| GSE97050 | HLX | 3142 | A_23_P126266 | 0.2903 | 0.3314 | |
| SRP064894 | HLX | 3142 | RNAseq | 1.4300 | 0.0001 | |
| SRP133303 | HLX | 3142 | RNAseq | 0.5153 | 0.0592 | |
| SRP159526 | HLX | 3142 | RNAseq | 0.4798 | 0.1595 | |
| SRP219564 | HLX | 3142 | RNAseq | 0.5981 | 0.1934 | |
| TCGA | HLX | 3142 | RNAseq | 0.2972 | 0.0173 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by HLX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HLX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HLX | 3142 | 10 | 0 | 20 | |
| GSE20123 | HLX | 3142 | 10 | 0 | 20 | |
| GSE43470 | HLX | 3142 | 7 | 1 | 35 | |
| GSE46452 | HLX | 3142 | 3 | 1 | 55 | |
| GSE47630 | HLX | 3142 | 15 | 0 | 25 | |
| GSE54993 | HLX | 3142 | 0 | 6 | 64 | |
| GSE54994 | HLX | 3142 | 15 | 0 | 38 | |
| GSE60625 | HLX | 3142 | 0 | 0 | 11 | |
| GSE74703 | HLX | 3142 | 7 | 1 | 28 | |
| GSE74704 | HLX | 3142 | 4 | 0 | 16 | |
| TCGA | HLX | 3142 | 45 | 3 | 48 |
Total number of gains: 116; Total number of losses: 12; Total Number of normals: 360.
Somatic mutations of HLX:
Generating mutation plots.
Highly correlated genes for HLX:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HLX | FAIM2 | 0.733251 | 3 | 0 | 3 |
| HLX | MICAL1 | 0.721743 | 3 | 0 | 3 |
| HLX | GPR150 | 0.682678 | 3 | 0 | 3 |
| HLX | GNL1 | 0.679282 | 4 | 0 | 4 |
| HLX | ADA | 0.672899 | 4 | 0 | 4 |
| HLX | TLR9 | 0.671999 | 3 | 0 | 3 |
| HLX | MCEMP1 | 0.669984 | 4 | 0 | 4 |
| HLX | ZNF469 | 0.669651 | 7 | 0 | 6 |
| HLX | GPR26 | 0.666505 | 3 | 0 | 3 |
| HLX | PNMA2 | 0.664876 | 3 | 0 | 3 |
| HLX | PCOLCE | 0.662595 | 11 | 0 | 10 |
| HLX | PAG1 | 0.662543 | 7 | 0 | 5 |
| HLX | SIGLEC1 | 0.658286 | 5 | 0 | 5 |
| HLX | WNT2 | 0.657292 | 5 | 0 | 5 |
| HLX | PKDCC | 0.656011 | 4 | 0 | 4 |
| HLX | FMNL1 | 0.655084 | 5 | 0 | 5 |
| HLX | LILRA3 | 0.653545 | 5 | 0 | 3 |
| HLX | SIGLEC9 | 0.649408 | 4 | 0 | 4 |
| HLX | FNDC1 | 0.642794 | 6 | 0 | 6 |
| HLX | DKK2 | 0.642517 | 5 | 0 | 4 |
For details and further investigation, click here
