| Full name: Wnt family member 10B | Alias Symbol: WNT-12|SHFM6 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 7480 | HGNC ID: HGNC:12775 | Ensembl Gene: ENSG00000169884 | OMIM ID: 601906 |
| Drug and gene relationship at DGIdb | |||
WNT10B involved pathways:
Expression of WNT10B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WNT10B | 7480 | 206213_at | 0.0212 | 0.9554 | |
| GSE20347 | WNT10B | 7480 | 206213_at | 0.0084 | 0.9555 | |
| GSE23400 | WNT10B | 7480 | 206213_at | -0.2048 | 0.0002 | |
| GSE26886 | WNT10B | 7480 | 206213_at | 0.2909 | 0.0976 | |
| GSE29001 | WNT10B | 7480 | 206213_at | -0.2958 | 0.1336 | |
| GSE38129 | WNT10B | 7480 | 206213_at | -0.2109 | 0.2694 | |
| GSE45670 | WNT10B | 7480 | 206213_at | -0.0394 | 0.8174 | |
| GSE53622 | WNT10B | 7480 | 4357 | 0.3911 | 0.1670 | |
| GSE53624 | WNT10B | 7480 | 4357 | 0.1308 | 0.5211 | |
| GSE63941 | WNT10B | 7480 | 206213_at | 0.6022 | 0.0401 | |
| GSE77861 | WNT10B | 7480 | 206213_at | 0.0443 | 0.7910 | |
| SRP064894 | WNT10B | 7480 | RNAseq | -1.0334 | 0.0041 | |
| SRP133303 | WNT10B | 7480 | RNAseq | -0.6962 | 0.1402 | |
| SRP159526 | WNT10B | 7480 | RNAseq | 0.4694 | 0.6050 | |
| SRP219564 | WNT10B | 7480 | RNAseq | 0.5784 | 0.2431 | |
| TCGA | WNT10B | 7480 | RNAseq | 0.4167 | 0.1757 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by WNT10B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WNT10B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WNT10B | 7480 | 6 | 1 | 23 | |
| GSE20123 | WNT10B | 7480 | 6 | 1 | 23 | |
| GSE43470 | WNT10B | 7480 | 4 | 1 | 38 | |
| GSE46452 | WNT10B | 7480 | 8 | 1 | 50 | |
| GSE47630 | WNT10B | 7480 | 11 | 2 | 27 | |
| GSE54993 | WNT10B | 7480 | 0 | 5 | 65 | |
| GSE54994 | WNT10B | 7480 | 4 | 1 | 48 | |
| GSE60625 | WNT10B | 7480 | 0 | 0 | 11 | |
| GSE74703 | WNT10B | 7480 | 4 | 1 | 31 | |
| GSE74704 | WNT10B | 7480 | 4 | 1 | 15 | |
| TCGA | WNT10B | 7480 | 16 | 14 | 66 |
Total number of gains: 63; Total number of losses: 28; Total Number of normals: 397.
Somatic mutations of WNT10B:
Generating mutation plots.
Highly correlated genes for WNT10B:
Showing top 20/628 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WNT10B | CHGA | 0.715676 | 3 | 0 | 3 |
| WNT10B | PSG5 | 0.698053 | 3 | 0 | 3 |
| WNT10B | SMARCD1 | 0.678652 | 3 | 0 | 3 |
| WNT10B | DRP2 | 0.673814 | 4 | 0 | 4 |
| WNT10B | ZFHX2 | 0.667273 | 5 | 0 | 5 |
| WNT10B | TTC9B | 0.66622 | 3 | 0 | 3 |
| WNT10B | IHH | 0.666026 | 5 | 0 | 5 |
| WNT10B | KRT35 | 0.665119 | 3 | 0 | 3 |
| WNT10B | NOS1 | 0.658521 | 6 | 0 | 5 |
| WNT10B | C2orf72 | 0.65689 | 6 | 0 | 5 |
| WNT10B | FGF21 | 0.653238 | 4 | 0 | 4 |
| WNT10B | PPP2R2B | 0.651731 | 5 | 0 | 5 |
| WNT10B | LTK | 0.651033 | 5 | 0 | 5 |
| WNT10B | IL13 | 0.647959 | 4 | 0 | 4 |
| WNT10B | IFITM10 | 0.646966 | 3 | 0 | 3 |
| WNT10B | TRIM62 | 0.636977 | 3 | 0 | 3 |
| WNT10B | MYOG | 0.636534 | 6 | 0 | 4 |
| WNT10B | GABRA6 | 0.63638 | 3 | 0 | 3 |
| WNT10B | CRYBB1 | 0.635921 | 5 | 0 | 3 |
| WNT10B | CPN1 | 0.635582 | 4 | 0 | 3 |
For details and further investigation, click here
