| Full name: signal regulatory protein beta 2 | Alias Symbol: dJ776F14.2 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 284759 | HGNC ID: HGNC:16247 | Ensembl Gene: ENSG00000196209 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SIRPB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SIRPB2 | 284759 | 1559034_at | 0.2445 | 0.4898 | |
| GSE26886 | SIRPB2 | 284759 | 1559034_at | 0.1940 | 0.0908 | |
| GSE45670 | SIRPB2 | 284759 | 1559034_at | 0.2317 | 0.0255 | |
| GSE53622 | SIRPB2 | 284759 | 23657 | 0.4054 | 0.0000 | |
| GSE53624 | SIRPB2 | 284759 | 23657 | 0.2299 | 0.0017 | |
| GSE63941 | SIRPB2 | 284759 | 1559034_at | 0.0592 | 0.7252 | |
| GSE77861 | SIRPB2 | 284759 | 1559034_at | 0.0722 | 0.3973 | |
| GSE97050 | SIRPB2 | 284759 | A_24_P202840 | 0.1994 | 0.3828 | |
| SRP133303 | SIRPB2 | 284759 | RNAseq | 0.4083 | 0.1455 | |
| SRP159526 | SIRPB2 | 284759 | RNAseq | 0.6561 | 0.4344 | |
| SRP219564 | SIRPB2 | 284759 | RNAseq | 0.9050 | 0.0521 | |
| TCGA | SIRPB2 | 284759 | RNAseq | 0.0346 | 0.8964 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SIRPB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SIRPB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SIRPB2 | 284759 | 13 | 3 | 14 | |
| GSE20123 | SIRPB2 | 284759 | 14 | 3 | 13 | |
| GSE43470 | SIRPB2 | 284759 | 11 | 1 | 31 | |
| GSE46452 | SIRPB2 | 284759 | 26 | 1 | 32 | |
| GSE47630 | SIRPB2 | 284759 | 19 | 4 | 17 | |
| GSE54993 | SIRPB2 | 284759 | 2 | 14 | 54 | |
| GSE54994 | SIRPB2 | 284759 | 24 | 2 | 27 | |
| GSE60625 | SIRPB2 | 284759 | 0 | 0 | 11 | |
| GSE74703 | SIRPB2 | 284759 | 10 | 1 | 25 | |
| GSE74704 | SIRPB2 | 284759 | 9 | 1 | 10 | |
| TCGA | SIRPB2 | 284759 | 40 | 11 | 45 |
Total number of gains: 168; Total number of losses: 41; Total Number of normals: 279.
Somatic mutations of SIRPB2:
Generating mutation plots.
Highly correlated genes for SIRPB2:
Showing top 20/104 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SIRPB2 | HDGFL1 | 0.715024 | 3 | 0 | 3 |
| SIRPB2 | DSCAM | 0.680309 | 3 | 0 | 3 |
| SIRPB2 | SNAI1 | 0.661268 | 3 | 0 | 3 |
| SIRPB2 | ANGPT4 | 0.647371 | 3 | 0 | 3 |
| SIRPB2 | FLOT1 | 0.640239 | 3 | 0 | 3 |
| SIRPB2 | CPN1 | 0.639626 | 3 | 0 | 3 |
| SIRPB2 | TBX2 | 0.63565 | 3 | 0 | 3 |
| SIRPB2 | CIB3 | 0.626244 | 3 | 0 | 3 |
| SIRPB2 | GHSR | 0.624422 | 4 | 0 | 3 |
| SIRPB2 | TMEM179 | 0.615553 | 3 | 0 | 3 |
| SIRPB2 | NPAS1 | 0.614651 | 3 | 0 | 3 |
| SIRPB2 | TUBAL3 | 0.613376 | 3 | 0 | 3 |
| SIRPB2 | KCTD19 | 0.60702 | 4 | 0 | 4 |
| SIRPB2 | MMP19 | 0.606814 | 3 | 0 | 3 |
| SIRPB2 | CDRT15 | 0.60363 | 4 | 0 | 3 |
| SIRPB2 | SUN5 | 0.603132 | 3 | 0 | 3 |
| SIRPB2 | DEFB128 | 0.598976 | 3 | 0 | 3 |
| SIRPB2 | DHRS7C | 0.598248 | 4 | 0 | 3 |
| SIRPB2 | NEUROG1 | 0.587777 | 4 | 0 | 3 |
| SIRPB2 | HOXB5 | 0.586833 | 4 | 0 | 3 |
For details and further investigation, click here
