| Full name: solute carrier family 12 member 8 | Alias Symbol: CCC9 | ||
| Type: protein-coding gene | Cytoband: 3q21.2 | ||
| Entrez ID: 84561 | HGNC ID: HGNC:15595 | Ensembl Gene: ENSG00000221955 | OMIM ID: 611316 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC12A8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC12A8 | 84561 | 219874_at | 0.7183 | 0.2781 | |
| GSE20347 | SLC12A8 | 84561 | 219874_at | 1.2715 | 0.0003 | |
| GSE23400 | SLC12A8 | 84561 | 219874_at | 0.5221 | 0.0000 | |
| GSE26886 | SLC12A8 | 84561 | 219874_at | 1.6424 | 0.0001 | |
| GSE29001 | SLC12A8 | 84561 | 219874_at | 0.9266 | 0.0744 | |
| GSE38129 | SLC12A8 | 84561 | 219874_at | 1.4535 | 0.0000 | |
| GSE45670 | SLC12A8 | 84561 | 219874_at | 1.0362 | 0.0072 | |
| GSE53622 | SLC12A8 | 84561 | 70489 | 1.4534 | 0.0000 | |
| GSE53624 | SLC12A8 | 84561 | 70489 | 1.1625 | 0.0000 | |
| GSE63941 | SLC12A8 | 84561 | 219874_at | -2.1196 | 0.0645 | |
| GSE77861 | SLC12A8 | 84561 | 219874_at | 0.4154 | 0.2969 | |
| GSE97050 | SLC12A8 | 84561 | A_33_P3298861 | 1.2535 | 0.1195 | |
| SRP007169 | SLC12A8 | 84561 | RNAseq | 1.0929 | 0.0196 | |
| SRP008496 | SLC12A8 | 84561 | RNAseq | 1.3046 | 0.0002 | |
| SRP064894 | SLC12A8 | 84561 | RNAseq | 0.9213 | 0.0000 | |
| SRP133303 | SLC12A8 | 84561 | RNAseq | 1.1405 | 0.0000 | |
| SRP159526 | SLC12A8 | 84561 | RNAseq | 1.8063 | 0.0002 | |
| SRP193095 | SLC12A8 | 84561 | RNAseq | 0.9757 | 0.0000 | |
| SRP219564 | SLC12A8 | 84561 | RNAseq | 1.8814 | 0.0034 | |
| TCGA | SLC12A8 | 84561 | RNAseq | 0.5419 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by SLC12A8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC12A8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC12A8 | 84561 | 17 | 0 | 13 | |
| GSE20123 | SLC12A8 | 84561 | 17 | 0 | 13 | |
| GSE43470 | SLC12A8 | 84561 | 20 | 0 | 23 | |
| GSE46452 | SLC12A8 | 84561 | 14 | 5 | 40 | |
| GSE47630 | SLC12A8 | 84561 | 17 | 4 | 19 | |
| GSE54993 | SLC12A8 | 84561 | 2 | 7 | 61 | |
| GSE54994 | SLC12A8 | 84561 | 31 | 3 | 19 | |
| GSE60625 | SLC12A8 | 84561 | 0 | 6 | 5 | |
| GSE74703 | SLC12A8 | 84561 | 17 | 0 | 19 | |
| GSE74704 | SLC12A8 | 84561 | 13 | 0 | 7 | |
| TCGA | SLC12A8 | 84561 | 56 | 6 | 34 |
Total number of gains: 204; Total number of losses: 31; Total Number of normals: 253.
Somatic mutations of SLC12A8:
Generating mutation plots.
Highly correlated genes for SLC12A8:
Showing top 20/625 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC12A8 | SHKBP1 | 0.810488 | 3 | 0 | 3 |
| SLC12A8 | SLC19A1 | 0.71391 | 3 | 0 | 3 |
| SLC12A8 | FANCD2 | 0.690374 | 3 | 0 | 3 |
| SLC12A8 | RAP2C-AS1 | 0.677862 | 3 | 0 | 3 |
| SLC12A8 | PVT1 | 0.670035 | 3 | 0 | 3 |
| SLC12A8 | C19orf48 | 0.669616 | 3 | 0 | 3 |
| SLC12A8 | UCN2 | 0.662754 | 3 | 0 | 3 |
| SLC12A8 | CPXM1 | 0.661911 | 4 | 0 | 4 |
| SLC12A8 | ESCO2 | 0.655625 | 4 | 0 | 3 |
| SLC12A8 | ZBTB9 | 0.650947 | 4 | 0 | 3 |
| SLC12A8 | FSCN1 | 0.644945 | 9 | 0 | 8 |
| SLC12A8 | ZNF319 | 0.643948 | 3 | 0 | 3 |
| SLC12A8 | CENPW | 0.642473 | 5 | 0 | 4 |
| SLC12A8 | FZD6 | 0.63651 | 7 | 0 | 6 |
| SLC12A8 | MYBL2 | 0.633133 | 10 | 0 | 9 |
| SLC12A8 | YDJC | 0.63049 | 7 | 0 | 6 |
| SLC12A8 | PDSS1 | 0.630348 | 5 | 0 | 4 |
| SLC12A8 | PUS7 | 0.62981 | 8 | 0 | 7 |
| SLC12A8 | AP1M1 | 0.629663 | 3 | 0 | 3 |
| SLC12A8 | PLEKHG4B | 0.627232 | 5 | 0 | 4 |
For details and further investigation, click here
