| Full name: SH3KBP1 binding protein 1 | Alias Symbol: PP203|Sb1 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 92799 | HGNC ID: HGNC:19214 | Ensembl Gene: ENSG00000160410 | OMIM ID: 617322 |
| Drug and gene relationship at DGIdb | |||
Expression of SHKBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHKBP1 | 92799 | 224846_at | 0.4712 | 0.1942 | |
| GSE26886 | SHKBP1 | 92799 | 224846_at | 0.0197 | 0.9270 | |
| GSE45670 | SHKBP1 | 92799 | 224846_at | 0.4072 | 0.0006 | |
| GSE53622 | SHKBP1 | 92799 | 33295 | 0.0998 | 0.2428 | |
| GSE53624 | SHKBP1 | 92799 | 33295 | 0.3189 | 0.0000 | |
| GSE63941 | SHKBP1 | 92799 | 224846_at | 0.7413 | 0.0216 | |
| GSE77861 | SHKBP1 | 92799 | 224846_at | 0.2952 | 0.1866 | |
| GSE97050 | SHKBP1 | 92799 | A_23_P130553 | 0.6022 | 0.1388 | |
| SRP007169 | SHKBP1 | 92799 | RNAseq | -0.6963 | 0.0694 | |
| SRP008496 | SHKBP1 | 92799 | RNAseq | -0.6689 | 0.0101 | |
| SRP064894 | SHKBP1 | 92799 | RNAseq | 0.7824 | 0.0003 | |
| SRP133303 | SHKBP1 | 92799 | RNAseq | 0.2805 | 0.1189 | |
| SRP159526 | SHKBP1 | 92799 | RNAseq | 0.1870 | 0.4607 | |
| SRP193095 | SHKBP1 | 92799 | RNAseq | 0.2224 | 0.0853 | |
| SRP219564 | SHKBP1 | 92799 | RNAseq | 0.4941 | 0.1108 | |
| TCGA | SHKBP1 | 92799 | RNAseq | 0.1584 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SHKBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SHKBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHKBP1 | 92799 | 6 | 5 | 19 | |
| GSE20123 | SHKBP1 | 92799 | 6 | 4 | 20 | |
| GSE43470 | SHKBP1 | 92799 | 3 | 9 | 31 | |
| GSE46452 | SHKBP1 | 92799 | 48 | 1 | 10 | |
| GSE47630 | SHKBP1 | 92799 | 9 | 5 | 26 | |
| GSE54993 | SHKBP1 | 92799 | 17 | 4 | 49 | |
| GSE54994 | SHKBP1 | 92799 | 8 | 9 | 36 | |
| GSE60625 | SHKBP1 | 92799 | 9 | 0 | 2 | |
| GSE74703 | SHKBP1 | 92799 | 3 | 6 | 27 | |
| GSE74704 | SHKBP1 | 92799 | 6 | 2 | 12 | |
| TCGA | SHKBP1 | 92799 | 14 | 16 | 66 |
Total number of gains: 129; Total number of losses: 61; Total Number of normals: 298.
Somatic mutations of SHKBP1:
Generating mutation plots.
Highly correlated genes for SHKBP1:
Showing top 20/467 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHKBP1 | SLC12A8 | 0.810488 | 3 | 0 | 3 |
| SHKBP1 | CALR | 0.794878 | 3 | 0 | 3 |
| SHKBP1 | PRKCZ | 0.777509 | 3 | 0 | 3 |
| SHKBP1 | POLD1 | 0.732129 | 4 | 0 | 4 |
| SHKBP1 | HNRNPUL1 | 0.712659 | 3 | 0 | 3 |
| SHKBP1 | APOC1 | 0.705022 | 3 | 0 | 3 |
| SHKBP1 | PPP6R1 | 0.703123 | 3 | 0 | 3 |
| SHKBP1 | FBXO46 | 0.694274 | 4 | 0 | 4 |
| SHKBP1 | TAGLN2 | 0.692227 | 6 | 0 | 5 |
| SHKBP1 | RAD51AP1 | 0.689252 | 4 | 0 | 4 |
| SHKBP1 | NELFB | 0.686516 | 3 | 0 | 3 |
| SHKBP1 | CENPF | 0.681683 | 4 | 0 | 4 |
| SHKBP1 | ATP13A1 | 0.680314 | 5 | 0 | 5 |
| SHKBP1 | IKBKG | 0.673447 | 5 | 0 | 5 |
| SHKBP1 | RNASEH2A | 0.670734 | 5 | 0 | 5 |
| SHKBP1 | PAFAH1B3 | 0.670134 | 5 | 0 | 4 |
| SHKBP1 | TINCR | 0.667014 | 3 | 0 | 3 |
| SHKBP1 | TMEM63B | 0.665463 | 3 | 0 | 3 |
| SHKBP1 | STMN1 | 0.663128 | 4 | 0 | 4 |
| SHKBP1 | CXCL16 | 0.662012 | 4 | 0 | 3 |
For details and further investigation, click here
