| Full name: carboxypeptidase X, M14 family member 1 | Alias Symbol: CPX-1|CPX1 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 56265 | HGNC ID: HGNC:15771 | Ensembl Gene: ENSG00000088882 | OMIM ID: 609555 |
| Drug and gene relationship at DGIdb | |||
Expression of CPXM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPXM1 | 56265 | 227860_at | 0.9707 | 0.3467 | |
| GSE26886 | CPXM1 | 56265 | 227860_at | 0.8235 | 0.0044 | |
| GSE45670 | CPXM1 | 56265 | 227860_at | 0.4784 | 0.1664 | |
| GSE53622 | CPXM1 | 56265 | 50201 | 1.8159 | 0.0000 | |
| GSE53624 | CPXM1 | 56265 | 50201 | 1.2401 | 0.0000 | |
| GSE63941 | CPXM1 | 56265 | 227860_at | -0.0116 | 0.9669 | |
| GSE77861 | CPXM1 | 56265 | 227860_at | 0.1329 | 0.4830 | |
| GSE97050 | CPXM1 | 56265 | A_23_P6066 | 0.8066 | 0.1421 | |
| SRP007169 | CPXM1 | 56265 | RNAseq | 2.2135 | 0.0012 | |
| SRP008496 | CPXM1 | 56265 | RNAseq | 3.5748 | 0.0000 | |
| SRP064894 | CPXM1 | 56265 | RNAseq | 4.5285 | 0.0000 | |
| SRP133303 | CPXM1 | 56265 | RNAseq | 2.4131 | 0.0000 | |
| SRP159526 | CPXM1 | 56265 | RNAseq | 1.7095 | 0.0013 | |
| SRP219564 | CPXM1 | 56265 | RNAseq | 4.0262 | 0.0000 | |
| TCGA | CPXM1 | 56265 | RNAseq | 0.8960 | 0.0001 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by CPXM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPXM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPXM1 | 56265 | 12 | 3 | 15 | |
| GSE20123 | CPXM1 | 56265 | 13 | 3 | 14 | |
| GSE43470 | CPXM1 | 56265 | 10 | 1 | 32 | |
| GSE46452 | CPXM1 | 56265 | 26 | 1 | 32 | |
| GSE47630 | CPXM1 | 56265 | 18 | 4 | 18 | |
| GSE54993 | CPXM1 | 56265 | 2 | 14 | 54 | |
| GSE54994 | CPXM1 | 56265 | 24 | 2 | 27 | |
| GSE60625 | CPXM1 | 56265 | 0 | 0 | 11 | |
| GSE74703 | CPXM1 | 56265 | 9 | 1 | 26 | |
| GSE74704 | CPXM1 | 56265 | 8 | 1 | 11 | |
| TCGA | CPXM1 | 56265 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of CPXM1:
Generating mutation plots.
Highly correlated genes for CPXM1:
Showing top 20/438 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPXM1 | NGFR | 0.726592 | 3 | 0 | 3 |
| CPXM1 | METTL7B | 0.722488 | 4 | 0 | 4 |
| CPXM1 | P4HA1 | 0.707203 | 4 | 0 | 4 |
| CPXM1 | PTK2B | 0.702823 | 3 | 0 | 3 |
| CPXM1 | SLAMF8 | 0.699723 | 4 | 0 | 4 |
| CPXM1 | GXYLT2 | 0.69157 | 3 | 0 | 3 |
| CPXM1 | IL2RB | 0.689059 | 3 | 0 | 3 |
| CPXM1 | TFPI2 | 0.686664 | 3 | 0 | 3 |
| CPXM1 | COL1A1 | 0.669596 | 7 | 0 | 6 |
| CPXM1 | COL4A1 | 0.666848 | 5 | 0 | 5 |
| CPXM1 | IL4I1 | 0.663555 | 5 | 0 | 5 |
| CPXM1 | SLC12A8 | 0.661911 | 4 | 0 | 4 |
| CPXM1 | EDARADD | 0.65918 | 3 | 0 | 3 |
| CPXM1 | NKX2-2 | 0.657939 | 3 | 0 | 3 |
| CPXM1 | COL5A1 | 0.655119 | 8 | 0 | 6 |
| CPXM1 | GAL3ST4 | 0.65453 | 4 | 0 | 4 |
| CPXM1 | PILRA | 0.648272 | 4 | 0 | 4 |
| CPXM1 | RCN3 | 0.645796 | 5 | 0 | 4 |
| CPXM1 | ANXA10 | 0.644884 | 3 | 0 | 3 |
| CPXM1 | PTGIR | 0.644518 | 4 | 0 | 4 |
For details and further investigation, click here
