| Full name: solute carrier family 16 member 8 | Alias Symbol: MCT3|REMP | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 23539 | HGNC ID: HGNC:16270 | Ensembl Gene: ENSG00000100156 | OMIM ID: 610409 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC16A8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC16A8 | 23539 | 220455_at | -0.0200 | 0.9367 | |
| GSE20347 | SLC16A8 | 23539 | 220455_at | -0.0157 | 0.8571 | |
| GSE23400 | SLC16A8 | 23539 | 220455_at | -0.1070 | 0.0152 | |
| GSE26886 | SLC16A8 | 23539 | 220455_at | -0.0142 | 0.9379 | |
| GSE29001 | SLC16A8 | 23539 | 220455_at | 0.3609 | 0.0476 | |
| GSE38129 | SLC16A8 | 23539 | 220455_at | -0.1131 | 0.1499 | |
| GSE45670 | SLC16A8 | 23539 | 220455_at | 0.1632 | 0.1212 | |
| GSE53622 | SLC16A8 | 23539 | 23879 | 0.2549 | 0.0510 | |
| GSE53624 | SLC16A8 | 23539 | 23879 | 0.2011 | 0.2144 | |
| GSE63941 | SLC16A8 | 23539 | 220455_at | -0.1005 | 0.7206 | |
| GSE77861 | SLC16A8 | 23539 | 220455_at | -0.0079 | 0.9712 | |
| SRP133303 | SLC16A8 | 23539 | RNAseq | 0.0848 | 0.7899 | |
| SRP159526 | SLC16A8 | 23539 | RNAseq | 1.5661 | 0.0168 | |
| SRP219564 | SLC16A8 | 23539 | RNAseq | 0.1281 | 0.8427 | |
| TCGA | SLC16A8 | 23539 | RNAseq | 0.2709 | 0.3476 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC16A8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC16A8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC16A8 | 23539 | 6 | 5 | 19 | |
| GSE20123 | SLC16A8 | 23539 | 6 | 4 | 20 | |
| GSE43470 | SLC16A8 | 23539 | 6 | 5 | 32 | |
| GSE46452 | SLC16A8 | 23539 | 32 | 2 | 25 | |
| GSE47630 | SLC16A8 | 23539 | 9 | 4 | 27 | |
| GSE54993 | SLC16A8 | 23539 | 3 | 6 | 61 | |
| GSE54994 | SLC16A8 | 23539 | 9 | 7 | 37 | |
| GSE60625 | SLC16A8 | 23539 | 5 | 0 | 6 | |
| GSE74703 | SLC16A8 | 23539 | 5 | 4 | 27 | |
| GSE74704 | SLC16A8 | 23539 | 3 | 2 | 15 | |
| TCGA | SLC16A8 | 23539 | 27 | 15 | 54 |
Total number of gains: 111; Total number of losses: 54; Total Number of normals: 323.
Somatic mutations of SLC16A8:
Generating mutation plots.
Highly correlated genes for SLC16A8:
Showing top 20/449 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC16A8 | PTH | 0.742159 | 3 | 0 | 3 |
| SLC16A8 | MEFV | 0.724938 | 3 | 0 | 3 |
| SLC16A8 | EVX1 | 0.69651 | 4 | 0 | 4 |
| SLC16A8 | E2F4 | 0.688883 | 3 | 0 | 3 |
| SLC16A8 | GDF11 | 0.686584 | 3 | 0 | 3 |
| SLC16A8 | FAM215A | 0.685496 | 4 | 0 | 4 |
| SLC16A8 | MYOZ3 | 0.682101 | 3 | 0 | 3 |
| SLC16A8 | DRD2 | 0.682002 | 3 | 0 | 3 |
| SLC16A8 | KANSL3 | 0.681665 | 3 | 0 | 3 |
| SLC16A8 | IFFO1 | 0.681333 | 3 | 0 | 3 |
| SLC16A8 | SLC45A2 | 0.67201 | 3 | 0 | 3 |
| SLC16A8 | OLFM1 | 0.670403 | 3 | 0 | 3 |
| SLC16A8 | POU2F2 | 0.664595 | 5 | 0 | 5 |
| SLC16A8 | IGF2-AS | 0.664322 | 4 | 0 | 4 |
| SLC16A8 | IFNA21 | 0.662953 | 4 | 0 | 4 |
| SLC16A8 | GYPA | 0.661005 | 3 | 0 | 3 |
| SLC16A8 | CCL1 | 0.660478 | 4 | 0 | 4 |
| SLC16A8 | CIITA | 0.660355 | 3 | 0 | 3 |
| SLC16A8 | GDF2 | 0.653516 | 4 | 0 | 4 |
| SLC16A8 | SYT5 | 0.652764 | 3 | 0 | 3 |
For details and further investigation, click here
