| Full name: solute carrier family 1 member 1 | Alias Symbol: EAAC1|EAAT3 | ||
| Type: protein-coding gene | Cytoband: 9p24.2 | ||
| Entrez ID: 6505 | HGNC ID: HGNC:10939 | Ensembl Gene: ENSG00000106688 | OMIM ID: 133550 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC1A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC1A1 | 6505 | 213664_at | -0.3500 | 0.7476 | |
| GSE20347 | SLC1A1 | 6505 | 213664_at | -0.6238 | 0.0577 | |
| GSE23400 | SLC1A1 | 6505 | 206396_at | -0.1044 | 0.0039 | |
| GSE26886 | SLC1A1 | 6505 | 213664_at | -0.5258 | 0.3172 | |
| GSE29001 | SLC1A1 | 6505 | 213664_at | -1.1491 | 0.0062 | |
| GSE38129 | SLC1A1 | 6505 | 213664_at | -0.5734 | 0.0377 | |
| GSE45670 | SLC1A1 | 6505 | 213664_at | -0.0964 | 0.8675 | |
| GSE53622 | SLC1A1 | 6505 | 97994 | -0.7987 | 0.0000 | |
| GSE53624 | SLC1A1 | 6505 | 97994 | -0.7735 | 0.0000 | |
| GSE63941 | SLC1A1 | 6505 | 213664_at | -3.8329 | 0.0040 | |
| GSE77861 | SLC1A1 | 6505 | 206396_at | -0.0671 | 0.4296 | |
| GSE97050 | SLC1A1 | 6505 | A_23_P216468 | 0.1888 | 0.4907 | |
| SRP007169 | SLC1A1 | 6505 | RNAseq | -0.0777 | 0.9240 | |
| SRP008496 | SLC1A1 | 6505 | RNAseq | -0.6856 | 0.1874 | |
| SRP064894 | SLC1A1 | 6505 | RNAseq | 0.0910 | 0.7703 | |
| SRP133303 | SLC1A1 | 6505 | RNAseq | -0.1523 | 0.6136 | |
| SRP159526 | SLC1A1 | 6505 | RNAseq | -1.5150 | 0.0000 | |
| SRP193095 | SLC1A1 | 6505 | RNAseq | -1.2372 | 0.0000 | |
| SRP219564 | SLC1A1 | 6505 | RNAseq | -0.2534 | 0.6925 | |
| TCGA | SLC1A1 | 6505 | RNAseq | -0.9467 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SLC1A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC1A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC1A1 | 6505 | 1 | 17 | 12 | |
| GSE20123 | SLC1A1 | 6505 | 1 | 16 | 13 | |
| GSE43470 | SLC1A1 | 6505 | 4 | 12 | 27 | |
| GSE46452 | SLC1A1 | 6505 | 2 | 23 | 34 | |
| GSE47630 | SLC1A1 | 6505 | 5 | 26 | 9 | |
| GSE54993 | SLC1A1 | 6505 | 6 | 3 | 61 | |
| GSE54994 | SLC1A1 | 6505 | 9 | 17 | 27 | |
| GSE60625 | SLC1A1 | 6505 | 0 | 2 | 9 | |
| GSE74703 | SLC1A1 | 6505 | 4 | 9 | 23 | |
| GSE74704 | SLC1A1 | 6505 | 0 | 12 | 8 | |
| TCGA | SLC1A1 | 6505 | 14 | 50 | 32 |
Total number of gains: 46; Total number of losses: 187; Total Number of normals: 255.
Somatic mutations of SLC1A1:
Generating mutation plots.
Highly correlated genes for SLC1A1:
Showing top 20/247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC1A1 | OR7E24 | 0.761352 | 3 | 0 | 3 |
| SLC1A1 | IRAK3 | 0.72656 | 3 | 0 | 3 |
| SLC1A1 | ARHGAP31 | 0.696911 | 4 | 0 | 4 |
| SLC1A1 | PIP5K1B | 0.692847 | 3 | 0 | 3 |
| SLC1A1 | BMP6 | 0.692589 | 4 | 0 | 3 |
| SLC1A1 | FBXO4 | 0.690334 | 3 | 0 | 3 |
| SLC1A1 | AP3M1 | 0.686975 | 3 | 0 | 3 |
| SLC1A1 | PARP16 | 0.678829 | 3 | 0 | 3 |
| SLC1A1 | HSD11B1 | 0.658117 | 3 | 0 | 3 |
| SLC1A1 | NDN | 0.657694 | 3 | 0 | 3 |
| SLC1A1 | LPIN2 | 0.656232 | 4 | 0 | 3 |
| SLC1A1 | PSEN2 | 0.65566 | 3 | 0 | 3 |
| SLC1A1 | ABHD14B | 0.650336 | 3 | 0 | 3 |
| SLC1A1 | MCPH1 | 0.647889 | 3 | 0 | 3 |
| SLC1A1 | ZNF627 | 0.647631 | 4 | 0 | 3 |
| SLC1A1 | ARHGEF6 | 0.644211 | 5 | 0 | 4 |
| SLC1A1 | ARSK | 0.641992 | 3 | 0 | 3 |
| SLC1A1 | GLIS3 | 0.636254 | 3 | 0 | 3 |
| SLC1A1 | RBBP9 | 0.631455 | 3 | 0 | 3 |
| SLC1A1 | ASL | 0.631434 | 3 | 0 | 3 |
For details and further investigation, click here
