| Full name: F-box protein 4 | Alias Symbol: FBX4 | ||
| Type: protein-coding gene | Cytoband: 5p13.1 | ||
| Entrez ID: 26272 | HGNC ID: HGNC:13583 | Ensembl Gene: ENSG00000151876 | OMIM ID: 609090 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO4 | 26272 | 223493_at | -0.0615 | 0.9099 | |
| GSE20347 | FBXO4 | 26272 | 220550_at | 0.0072 | 0.8969 | |
| GSE23400 | FBXO4 | 26272 | 220550_at | -0.0630 | 0.0151 | |
| GSE26886 | FBXO4 | 26272 | 223493_at | 0.3503 | 0.2819 | |
| GSE29001 | FBXO4 | 26272 | 220550_at | -0.0182 | 0.8870 | |
| GSE38129 | FBXO4 | 26272 | 220550_at | 0.0066 | 0.8922 | |
| GSE45670 | FBXO4 | 26272 | 223493_at | -0.0783 | 0.7567 | |
| GSE53622 | FBXO4 | 26272 | 80946 | 0.1814 | 0.0285 | |
| GSE53624 | FBXO4 | 26272 | 80946 | 0.0794 | 0.5469 | |
| GSE63941 | FBXO4 | 26272 | 223493_at | -0.4915 | 0.6483 | |
| GSE77861 | FBXO4 | 26272 | 223493_at | -0.0044 | 0.9903 | |
| GSE97050 | FBXO4 | 26272 | A_24_P171873 | 0.0887 | 0.7287 | |
| SRP007169 | FBXO4 | 26272 | RNAseq | -0.1410 | 0.8332 | |
| SRP008496 | FBXO4 | 26272 | RNAseq | 0.2924 | 0.5683 | |
| SRP064894 | FBXO4 | 26272 | RNAseq | 0.0522 | 0.7500 | |
| SRP133303 | FBXO4 | 26272 | RNAseq | -0.0340 | 0.8263 | |
| SRP159526 | FBXO4 | 26272 | RNAseq | -0.1507 | 0.6894 | |
| SRP193095 | FBXO4 | 26272 | RNAseq | -0.4598 | 0.0024 | |
| SRP219564 | FBXO4 | 26272 | RNAseq | 0.0255 | 0.9447 | |
| TCGA | FBXO4 | 26272 | RNAseq | 0.1134 | 0.1459 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXO4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO4 | 26272 | 9 | 0 | 21 | |
| GSE20123 | FBXO4 | 26272 | 9 | 0 | 21 | |
| GSE43470 | FBXO4 | 26272 | 17 | 0 | 26 | |
| GSE46452 | FBXO4 | 26272 | 5 | 22 | 32 | |
| GSE47630 | FBXO4 | 26272 | 6 | 12 | 22 | |
| GSE54993 | FBXO4 | 26272 | 6 | 3 | 61 | |
| GSE54994 | FBXO4 | 26272 | 24 | 2 | 27 | |
| GSE60625 | FBXO4 | 26272 | 0 | 0 | 11 | |
| GSE74703 | FBXO4 | 26272 | 13 | 0 | 23 | |
| GSE74704 | FBXO4 | 26272 | 8 | 0 | 12 | |
| TCGA | FBXO4 | 26272 | 52 | 6 | 38 |
Total number of gains: 149; Total number of losses: 45; Total Number of normals: 294.
Somatic mutations of FBXO4:
Generating mutation plots.
Highly correlated genes for FBXO4:
Showing top 20/168 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO4 | DCTD | 0.757695 | 3 | 0 | 3 |
| FBXO4 | SMIM20 | 0.728445 | 3 | 0 | 3 |
| FBXO4 | POMZP3 | 0.70542 | 3 | 0 | 3 |
| FBXO4 | SLC1A1 | 0.690334 | 3 | 0 | 3 |
| FBXO4 | CLDN12 | 0.687695 | 3 | 0 | 3 |
| FBXO4 | TMEM218 | 0.680794 | 4 | 0 | 4 |
| FBXO4 | CSTF1 | 0.679964 | 3 | 0 | 3 |
| FBXO4 | RMND1 | 0.665193 | 3 | 0 | 3 |
| FBXO4 | ZNF658 | 0.662062 | 3 | 0 | 3 |
| FBXO4 | KCNE3 | 0.651597 | 4 | 0 | 4 |
| FBXO4 | CLCN4 | 0.648862 | 4 | 0 | 3 |
| FBXO4 | CRADD | 0.644289 | 3 | 0 | 3 |
| FBXO4 | RFXAP | 0.643162 | 3 | 0 | 3 |
| FBXO4 | PTPRJ | 0.641846 | 3 | 0 | 3 |
| FBXO4 | TUBGCP4 | 0.641345 | 3 | 0 | 3 |
| FBXO4 | PARP16 | 0.640631 | 5 | 0 | 4 |
| FBXO4 | B3GALT5 | 0.637799 | 3 | 0 | 3 |
| FBXO4 | LMBR1 | 0.636664 | 3 | 0 | 3 |
| FBXO4 | TMEM123 | 0.631121 | 4 | 0 | 3 |
| FBXO4 | RFC1 | 0.62905 | 5 | 0 | 4 |
For details and further investigation, click here
