| Full name: family with sequence similarity 110 member C | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p25.3 | ||
| Entrez ID: 642273 | HGNC ID: HGNC:33340 | Ensembl Gene: ENSG00000184731 | OMIM ID: 611395 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM110C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM110C | 642273 | 226863_at | -1.0588 | 0.1383 | |
| GSE26886 | FAM110C | 642273 | 226863_at | -0.5648 | 0.0536 | |
| GSE45670 | FAM110C | 642273 | 226863_at | -0.2306 | 0.4421 | |
| GSE53622 | FAM110C | 642273 | 57807 | -0.7321 | 0.0022 | |
| GSE53624 | FAM110C | 642273 | 57807 | -1.1297 | 0.0000 | |
| GSE63941 | FAM110C | 642273 | 226863_at | 4.6120 | 0.0005 | |
| GSE77861 | FAM110C | 642273 | 226863_at | -0.5260 | 0.2035 | |
| GSE97050 | FAM110C | 642273 | A_24_P50248 | 0.2440 | 0.7141 | |
| SRP007169 | FAM110C | 642273 | RNAseq | -0.7993 | 0.0822 | |
| SRP008496 | FAM110C | 642273 | RNAseq | -0.5233 | 0.1944 | |
| SRP064894 | FAM110C | 642273 | RNAseq | -1.0998 | 0.0110 | |
| SRP133303 | FAM110C | 642273 | RNAseq | -0.8942 | 0.0069 | |
| SRP159526 | FAM110C | 642273 | RNAseq | -1.0056 | 0.1454 | |
| SRP193095 | FAM110C | 642273 | RNAseq | -0.6694 | 0.0067 | |
| SRP219564 | FAM110C | 642273 | RNAseq | -1.2257 | 0.2062 | |
| TCGA | FAM110C | 642273 | RNAseq | 0.4804 | 0.0138 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by FAM110C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM110C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM110C | 642273 | 8 | 2 | 20 | |
| GSE20123 | FAM110C | 642273 | 8 | 2 | 20 | |
| GSE43470 | FAM110C | 642273 | 2 | 2 | 39 | |
| GSE46452 | FAM110C | 642273 | 3 | 4 | 52 | |
| GSE47630 | FAM110C | 642273 | 7 | 0 | 33 | |
| GSE54993 | FAM110C | 642273 | 1 | 7 | 62 | |
| GSE54994 | FAM110C | 642273 | 13 | 0 | 40 | |
| GSE60625 | FAM110C | 642273 | 0 | 3 | 8 | |
| GSE74703 | FAM110C | 642273 | 2 | 0 | 34 | |
| GSE74704 | FAM110C | 642273 | 8 | 1 | 11 | |
| TCGA | FAM110C | 642273 | 32 | 5 | 59 |
Total number of gains: 84; Total number of losses: 26; Total Number of normals: 378.
Somatic mutations of FAM110C:
Generating mutation plots.
Highly correlated genes for FAM110C:
Showing top 20/754 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM110C | NUAK2 | 0.783128 | 3 | 0 | 3 |
| FAM110C | ANK3 | 0.760859 | 3 | 0 | 3 |
| FAM110C | CKMT1A | 0.743782 | 3 | 0 | 3 |
| FAM110C | FAM83G | 0.739632 | 5 | 0 | 5 |
| FAM110C | ARAP2 | 0.733976 | 3 | 0 | 3 |
| FAM110C | CDH1 | 0.73274 | 5 | 0 | 5 |
| FAM110C | DNASE1L1 | 0.719256 | 3 | 0 | 3 |
| FAM110C | EPGN | 0.714666 | 3 | 0 | 3 |
| FAM110C | ARRDC1 | 0.710072 | 5 | 0 | 5 |
| FAM110C | PHLDA1 | 0.708138 | 3 | 0 | 3 |
| FAM110C | CTNND1 | 0.702331 | 3 | 0 | 3 |
| FAM110C | PKP3 | 0.699152 | 7 | 0 | 7 |
| FAM110C | NIPAL1 | 0.698369 | 4 | 0 | 3 |
| FAM110C | SDC1 | 0.698277 | 4 | 0 | 4 |
| FAM110C | SLC22A18 | 0.697562 | 5 | 0 | 4 |
| FAM110C | SFN | 0.695133 | 7 | 0 | 6 |
| FAM110C | FZD10 | 0.690755 | 4 | 0 | 3 |
| FAM110C | LTA4H | 0.686619 | 3 | 0 | 3 |
| FAM110C | ELOVL1 | 0.686543 | 3 | 0 | 3 |
| FAM110C | SERPINB5 | 0.684776 | 5 | 0 | 5 |
For details and further investigation, click here
