| Full name: solute carrier family 24 member 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p11.23 | ||
| Entrez ID: 57419 | HGNC ID: HGNC:10977 | Ensembl Gene: ENSG00000185052 | OMIM ID: 609839 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC24A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC24A3 | 57419 | 219090_at | -0.9163 | 0.2254 | |
| GSE20347 | SLC24A3 | 57419 | 219090_at | -2.8000 | 0.0000 | |
| GSE23400 | SLC24A3 | 57419 | 219090_at | -1.4159 | 0.0000 | |
| GSE26886 | SLC24A3 | 57419 | 219090_at | -2.6199 | 0.0000 | |
| GSE29001 | SLC24A3 | 57419 | 57588_at | -2.2407 | 0.0002 | |
| GSE38129 | SLC24A3 | 57419 | 57588_at | -1.9167 | 0.0000 | |
| GSE45670 | SLC24A3 | 57419 | 57588_at | -1.4708 | 0.0075 | |
| GSE53622 | SLC24A3 | 57419 | 57908 | -1.5274 | 0.0000 | |
| GSE53624 | SLC24A3 | 57419 | 57908 | -2.2570 | 0.0000 | |
| GSE63941 | SLC24A3 | 57419 | 219090_at | -1.6204 | 0.0648 | |
| GSE77861 | SLC24A3 | 57419 | 219090_at | -2.2934 | 0.0003 | |
| GSE97050 | SLC24A3 | 57419 | A_23_P79978 | -0.8232 | 0.1838 | |
| SRP007169 | SLC24A3 | 57419 | RNAseq | -3.4026 | 0.0000 | |
| SRP008496 | SLC24A3 | 57419 | RNAseq | -3.0906 | 0.0000 | |
| SRP064894 | SLC24A3 | 57419 | RNAseq | -2.3124 | 0.0000 | |
| SRP133303 | SLC24A3 | 57419 | RNAseq | -1.5184 | 0.0000 | |
| SRP159526 | SLC24A3 | 57419 | RNAseq | -1.7150 | 0.0000 | |
| SRP193095 | SLC24A3 | 57419 | RNAseq | -1.5074 | 0.0000 | |
| SRP219564 | SLC24A3 | 57419 | RNAseq | -1.1997 | 0.1103 | |
| TCGA | SLC24A3 | 57419 | RNAseq | -0.0343 | 0.8337 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by SLC24A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC24A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC24A3 | 57419 | 13 | 2 | 15 | |
| GSE20123 | SLC24A3 | 57419 | 13 | 2 | 15 | |
| GSE43470 | SLC24A3 | 57419 | 11 | 1 | 31 | |
| GSE46452 | SLC24A3 | 57419 | 27 | 1 | 31 | |
| GSE47630 | SLC24A3 | 57419 | 17 | 4 | 19 | |
| GSE54993 | SLC24A3 | 57419 | 0 | 15 | 55 | |
| GSE54994 | SLC24A3 | 57419 | 26 | 2 | 25 | |
| GSE60625 | SLC24A3 | 57419 | 0 | 0 | 11 | |
| GSE74703 | SLC24A3 | 57419 | 8 | 1 | 27 | |
| GSE74704 | SLC24A3 | 57419 | 7 | 2 | 11 | |
| TCGA | SLC24A3 | 57419 | 44 | 11 | 41 |
Total number of gains: 166; Total number of losses: 41; Total Number of normals: 281.
Somatic mutations of SLC24A3:
Generating mutation plots.
Highly correlated genes for SLC24A3:
Showing top 20/1485 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC24A3 | SORT1 | 0.801259 | 9 | 0 | 9 |
| SLC24A3 | GYS2 | 0.793489 | 10 | 0 | 10 |
| SLC24A3 | EHD3 | 0.786624 | 11 | 0 | 11 |
| SLC24A3 | CWH43 | 0.774763 | 10 | 0 | 10 |
| SLC24A3 | MYZAP | 0.770509 | 3 | 0 | 3 |
| SLC24A3 | KIAA1211L | 0.767747 | 5 | 0 | 5 |
| SLC24A3 | RANBP9 | 0.767001 | 10 | 0 | 10 |
| SLC24A3 | UBL3 | 0.766673 | 12 | 0 | 11 |
| SLC24A3 | NAGK | 0.766642 | 10 | 0 | 10 |
| SLC24A3 | ENDOU | 0.765002 | 11 | 0 | 10 |
| SLC24A3 | RAB5A | 0.764334 | 10 | 0 | 10 |
| SLC24A3 | HPGD | 0.762805 | 10 | 0 | 10 |
| SLC24A3 | NPEPPS | 0.762029 | 10 | 0 | 10 |
| SLC24A3 | PDLIM2 | 0.75965 | 8 | 0 | 8 |
| SLC24A3 | DOCK9 | 0.758817 | 10 | 0 | 10 |
| SLC24A3 | GRN | 0.758685 | 8 | 0 | 8 |
| SLC24A3 | VAT1 | 0.758476 | 11 | 0 | 10 |
| SLC24A3 | ALDH9A1 | 0.758369 | 10 | 0 | 10 |
| SLC24A3 | ZCCHC9 | 0.757267 | 3 | 0 | 3 |
| SLC24A3 | CNN3 | 0.754573 | 8 | 0 | 8 |
For details and further investigation, click here
