NUP62

 

Full name: nucleoporin 62 Alias Symbol: p62|DKFZp547L134|IBSN|SNDI|MGC841|FLJ20822|FLJ43869
Type: protein-coding gene Cytoband: 19q13.33
Entrez ID: 23636 HGNC ID: HGNC:8066 Ensembl Gene: ENSG00000213024 OMIM ID: 605815
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NUP62:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUP62 23636 202153_s_at 0.8059 0.0907
GSE20347 NUP62 23636 202153_s_at 0.6344 0.0000
GSE23400 NUP62 23636 202153_s_at 0.7853 0.0000
GSE26886 NUP62 23636 202153_s_at 1.0318 0.0000
GSE29001 NUP62 23636 202153_s_at 1.1213 0.0000
GSE38129 NUP62 23636 202153_s_at 0.8227 0.0000
GSE45670 NUP62 23636 202153_s_at 0.5745 0.0000
GSE53622 NUP62 23636 119818 0.6278 0.0000
GSE53624 NUP62 23636 46832 0.8131 0.0000
GSE63941 NUP62 23636 202153_s_at 0.0638 0.8849
GSE77861 NUP62 23636 202153_s_at 0.7487 0.0124
GSE97050 NUP62 23636 A_33_P3418010 0.2861 0.2576
SRP007169 NUP62 23636 RNAseq 1.3767 0.0001
SRP008496 NUP62 23636 RNAseq 1.0937 0.0000
SRP064894 NUP62 23636 RNAseq 1.1358 0.0000
SRP133303 NUP62 23636 RNAseq 0.6968 0.0006
SRP159526 NUP62 23636 RNAseq 1.0155 0.0001
SRP193095 NUP62 23636 RNAseq 0.6856 0.0000
SRP219564 NUP62 23636 RNAseq 0.6896 0.0015
TCGA NUP62 23636 RNAseq 0.2727 0.0000

Upregulated datasets: 6; Downregulated datasets: 0.  

 

Survival by NUP62 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NUP62:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUP62 23636 4 4 22
GSE20123 NUP62 23636 4 3 23
GSE43470 NUP62 23636 5 11 27
GSE46452 NUP62 23636 45 1 13
GSE47630 NUP62 23636 10 6 24
GSE54993 NUP62 23636 17 4 49
GSE54994 NUP62 23636 4 14 35
GSE60625 NUP62 23636 9 0 2
GSE74703 NUP62 23636 5 7 24
GSE74704 NUP62 23636 4 1 15
TCGA NUP62 23636 14 18 64

Total number of gains: 121; Total number of losses: 69; Total Number of normals: 298.  

 

Somatic mutations of NUP62:

 

Generating mutation plots.

 

Highly correlated genes for NUP62:

 

Showing top 20/2120 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUP62USP410.7765303
NUP62PLXNA10.76783211011
NUP62SLC39A30.762084404
NUP62PARP120.76033911011
NUP62IPO90.756952908
NUP62WDR540.748349606
NUP62MARCKSL10.74552712011
NUP62CKS1B0.74456611011
NUP62DNMT10.74220313011
NUP62AGRN0.73908811011
NUP62MTBP0.737436505
NUP62MET0.736181909
NUP62DOCK60.735846404
NUP62DTL0.73528111011
NUP62MFAP20.73503311011
NUP62C1orf1120.730571909
NUP62GNPNAT10.728736303
NUP62ADAR0.72772912011
NUP62KIF2C0.72616311011
NUP62MYBL20.72606111011

For details and further investigation, click here