| Full name: solute carrier family 4 member 11 | Alias Symbol: dJ794I6.2|BTR1|NaBC1|FECD4 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 83959 | HGNC ID: HGNC:16438 | Ensembl Gene: ENSG00000088836 | OMIM ID: 610206 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC4A11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC4A11 | 83959 | 223748_at | 0.8698 | 0.0504 | |
| GSE26886 | SLC4A11 | 83959 | 223748_at | -0.0514 | 0.8958 | |
| GSE45670 | SLC4A11 | 83959 | 223748_at | 0.9836 | 0.0163 | |
| GSE53622 | SLC4A11 | 83959 | 86737 | 0.1758 | 0.0961 | |
| GSE53624 | SLC4A11 | 83959 | 22018 | 0.1204 | 0.4146 | |
| GSE63941 | SLC4A11 | 83959 | 223748_at | 0.5939 | 0.5165 | |
| GSE77861 | SLC4A11 | 83959 | 223748_at | 0.9452 | 0.0953 | |
| GSE97050 | SLC4A11 | 83959 | A_23_P154688 | 0.1433 | 0.7225 | |
| SRP007169 | SLC4A11 | 83959 | RNAseq | 1.0155 | 0.1456 | |
| SRP064894 | SLC4A11 | 83959 | RNAseq | 0.0081 | 0.9840 | |
| SRP133303 | SLC4A11 | 83959 | RNAseq | -0.2996 | 0.4987 | |
| SRP159526 | SLC4A11 | 83959 | RNAseq | 1.1500 | 0.0210 | |
| SRP193095 | SLC4A11 | 83959 | RNAseq | 0.5544 | 0.0322 | |
| SRP219564 | SLC4A11 | 83959 | RNAseq | -0.0755 | 0.9361 | |
| TCGA | SLC4A11 | 83959 | RNAseq | 0.8809 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC4A11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC4A11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC4A11 | 83959 | 12 | 3 | 15 | |
| GSE20123 | SLC4A11 | 83959 | 13 | 3 | 14 | |
| GSE43470 | SLC4A11 | 83959 | 10 | 1 | 32 | |
| GSE46452 | SLC4A11 | 83959 | 26 | 1 | 32 | |
| GSE47630 | SLC4A11 | 83959 | 18 | 4 | 18 | |
| GSE54993 | SLC4A11 | 83959 | 2 | 14 | 54 | |
| GSE54994 | SLC4A11 | 83959 | 24 | 2 | 27 | |
| GSE60625 | SLC4A11 | 83959 | 0 | 0 | 11 | |
| GSE74703 | SLC4A11 | 83959 | 9 | 1 | 26 | |
| GSE74704 | SLC4A11 | 83959 | 8 | 1 | 11 | |
| TCGA | SLC4A11 | 83959 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of SLC4A11:
Generating mutation plots.
Highly correlated genes for SLC4A11:
Showing top 20/94 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC4A11 | UBE2S | 0.769401 | 3 | 0 | 3 |
| SLC4A11 | LONP1 | 0.730427 | 3 | 0 | 3 |
| SLC4A11 | FURIN | 0.729641 | 3 | 0 | 3 |
| SLC4A11 | CEP19 | 0.710726 | 3 | 0 | 3 |
| SLC4A11 | CBX3 | 0.710051 | 3 | 0 | 3 |
| SLC4A11 | HOXC9 | 0.706358 | 3 | 0 | 3 |
| SLC4A11 | UBL4A | 0.702268 | 3 | 0 | 3 |
| SLC4A11 | FBRSL1 | 0.687378 | 4 | 0 | 3 |
| SLC4A11 | ZNF77 | 0.683136 | 3 | 0 | 3 |
| SLC4A11 | TAF5L | 0.681887 | 3 | 0 | 3 |
| SLC4A11 | TIMM50 | 0.678204 | 3 | 0 | 3 |
| SLC4A11 | SLC5A6 | 0.67725 | 4 | 0 | 3 |
| SLC4A11 | SDK1 | 0.676413 | 3 | 0 | 3 |
| SLC4A11 | SOX12 | 0.67609 | 4 | 0 | 4 |
| SLC4A11 | TNFAIP8L1 | 0.668435 | 3 | 0 | 3 |
| SLC4A11 | HMBS | 0.66109 | 5 | 0 | 4 |
| SLC4A11 | APBA2 | 0.656852 | 4 | 0 | 3 |
| SLC4A11 | IL27RA | 0.652977 | 4 | 0 | 3 |
| SLC4A11 | KIF4A | 0.652402 | 4 | 0 | 3 |
| SLC4A11 | CDC20 | 0.645036 | 3 | 0 | 3 |
For details and further investigation, click here
