| Full name: solute carrier family 5 member 6 | Alias Symbol: SMVT | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 8884 | HGNC ID: HGNC:11041 | Ensembl Gene: ENSG00000138074 | OMIM ID: 604024 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC5A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC5A6 | 8884 | 204087_s_at | 1.1763 | 0.0286 | |
| GSE20347 | SLC5A6 | 8884 | 204087_s_at | 0.6990 | 0.0052 | |
| GSE23400 | SLC5A6 | 8884 | 204087_s_at | 0.2142 | 0.0010 | |
| GSE26886 | SLC5A6 | 8884 | 204087_s_at | 0.5837 | 0.0132 | |
| GSE29001 | SLC5A6 | 8884 | 204087_s_at | 0.4017 | 0.0231 | |
| GSE38129 | SLC5A6 | 8884 | 204087_s_at | 0.7370 | 0.0002 | |
| GSE45670 | SLC5A6 | 8884 | 204087_s_at | 0.6397 | 0.0023 | |
| GSE53622 | SLC5A6 | 8884 | 79034 | 0.7477 | 0.0000 | |
| GSE53624 | SLC5A6 | 8884 | 98526 | 1.1067 | 0.0000 | |
| GSE63941 | SLC5A6 | 8884 | 204087_s_at | 0.6978 | 0.1567 | |
| GSE77861 | SLC5A6 | 8884 | 204087_s_at | 0.3315 | 0.0858 | |
| GSE97050 | SLC5A6 | 8884 | A_33_P3281465 | 0.4457 | 0.1818 | |
| SRP007169 | SLC5A6 | 8884 | RNAseq | 0.7099 | 0.0721 | |
| SRP008496 | SLC5A6 | 8884 | RNAseq | 0.8357 | 0.0133 | |
| SRP064894 | SLC5A6 | 8884 | RNAseq | 0.8407 | 0.0000 | |
| SRP133303 | SLC5A6 | 8884 | RNAseq | 0.8028 | 0.0000 | |
| SRP159526 | SLC5A6 | 8884 | RNAseq | 2.0571 | 0.0026 | |
| SRP193095 | SLC5A6 | 8884 | RNAseq | 0.6601 | 0.0000 | |
| SRP219564 | SLC5A6 | 8884 | RNAseq | 0.9283 | 0.0328 | |
| TCGA | SLC5A6 | 8884 | RNAseq | 0.2836 | 0.0001 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SLC5A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC5A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC5A6 | 8884 | 11 | 2 | 17 | |
| GSE20123 | SLC5A6 | 8884 | 11 | 2 | 17 | |
| GSE43470 | SLC5A6 | 8884 | 3 | 1 | 39 | |
| GSE46452 | SLC5A6 | 8884 | 3 | 4 | 52 | |
| GSE47630 | SLC5A6 | 8884 | 8 | 0 | 32 | |
| GSE54993 | SLC5A6 | 8884 | 0 | 6 | 64 | |
| GSE54994 | SLC5A6 | 8884 | 10 | 0 | 43 | |
| GSE60625 | SLC5A6 | 8884 | 0 | 3 | 8 | |
| GSE74703 | SLC5A6 | 8884 | 3 | 0 | 33 | |
| GSE74704 | SLC5A6 | 8884 | 9 | 1 | 10 | |
| TCGA | SLC5A6 | 8884 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of SLC5A6:
Generating mutation plots.
Highly correlated genes for SLC5A6:
Showing top 20/733 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC5A6 | MTBP | 0.744469 | 4 | 0 | 4 |
| SLC5A6 | NLRC5 | 0.737832 | 3 | 0 | 3 |
| SLC5A6 | CAD | 0.730125 | 12 | 0 | 11 |
| SLC5A6 | INSM1 | 0.723451 | 3 | 0 | 3 |
| SLC5A6 | FBRSL1 | 0.719885 | 5 | 0 | 5 |
| SLC5A6 | HOXC9 | 0.705011 | 5 | 0 | 5 |
| SLC5A6 | UBE2T | 0.695368 | 7 | 0 | 6 |
| SLC5A6 | RCCD1 | 0.680522 | 5 | 0 | 4 |
| SLC5A6 | MTFR2 | 0.679085 | 5 | 0 | 4 |
| SLC5A6 | SLC4A11 | 0.67725 | 4 | 0 | 3 |
| SLC5A6 | MND1 | 0.670328 | 6 | 0 | 6 |
| SLC5A6 | HCK | 0.66877 | 3 | 0 | 3 |
| SLC5A6 | TMEM216 | 0.658526 | 3 | 0 | 3 |
| SLC5A6 | TIMELESS | 0.656639 | 10 | 0 | 9 |
| SLC5A6 | HAUS8 | 0.656559 | 6 | 0 | 4 |
| SLC5A6 | SAFB | 0.655844 | 7 | 0 | 6 |
| SLC5A6 | ECE2 | 0.653797 | 7 | 0 | 7 |
| SLC5A6 | CDCA5 | 0.653267 | 8 | 0 | 6 |
| SLC5A6 | RAD51AP1 | 0.651822 | 12 | 0 | 11 |
| SLC5A6 | CENPF | 0.651544 | 11 | 0 | 10 |
For details and further investigation, click here
