TIMM50

 

Full name: translocase of inner mitochondrial membrane 50 Alias Symbol: TIM50L|TIM50
Type: protein-coding gene Cytoband: 19q13.2
Entrez ID: 92609 HGNC ID: HGNC:23656 Ensembl Gene: ENSG00000105197 OMIM ID: 607381
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TIMM50:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TIMM50 92609 224913_s_at 0.6624 0.0286
GSE20347 TIMM50 92609 217612_at 0.1500 0.3312
GSE23400 TIMM50 92609 217612_at 0.0807 0.0520
GSE26886 TIMM50 92609 224913_s_at 0.1146 0.5552
GSE29001 TIMM50 92609 217612_at 0.3116 0.0522
GSE38129 TIMM50 92609 217612_at 0.2089 0.0782
GSE45670 TIMM50 92609 224913_s_at 0.2764 0.0713
GSE53622 TIMM50 92609 5191 0.3520 0.0000
GSE53624 TIMM50 92609 5191 0.8078 0.0000
GSE63941 TIMM50 92609 224913_s_at 0.3475 0.4758
GSE77861 TIMM50 92609 224913_s_at 0.6643 0.0353
GSE97050 TIMM50 92609 A_23_P415882 0.2808 0.2349
SRP007169 TIMM50 92609 RNAseq 0.2931 0.3941
SRP008496 TIMM50 92609 RNAseq 0.2331 0.2773
SRP064894 TIMM50 92609 RNAseq 0.6211 0.0111
SRP133303 TIMM50 92609 RNAseq 0.4223 0.0014
SRP159526 TIMM50 92609 RNAseq 0.8208 0.0022
SRP193095 TIMM50 92609 RNAseq 0.1292 0.0790
SRP219564 TIMM50 92609 RNAseq 0.3853 0.2325
TCGA TIMM50 92609 RNAseq 0.1370 0.0119

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TIMM50 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TIMM50:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TIMM50 92609 7 4 19
GSE20123 TIMM50 92609 7 3 20
GSE43470 TIMM50 92609 3 11 29
GSE46452 TIMM50 92609 48 1 10
GSE47630 TIMM50 92609 9 5 26
GSE54993 TIMM50 92609 17 3 50
GSE54994 TIMM50 92609 7 9 37
GSE60625 TIMM50 92609 9 0 2
GSE74703 TIMM50 92609 3 7 26
GSE74704 TIMM50 92609 7 1 12
TCGA TIMM50 92609 14 16 66

Total number of gains: 131; Total number of losses: 60; Total Number of normals: 297.  

 

Somatic mutations of TIMM50:

 

Generating mutation plots.

 

Highly correlated genes for TIMM50:

 

Showing top 20/650 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TIMM50C19orf480.76301303
TIMM50GPRIN10.751027404
TIMM50BEND30.718002606
TIMM50SCYL10.706585303
TIMM50MTERF30.70655303
TIMM50CCDC860.696683404
TIMM50ZDHHC230.692093303
TIMM50DNMT10.691801606
TIMM50YIF1B0.691143606
TIMM50ZMYND150.687306303
TIMM50FBRSL10.684532403
TIMM50MSTO10.683097403
TIMM50SLC4A110.678204303
TIMM50HOMER30.674879605
TIMM50HOXD100.671775404
TIMM50LONP10.670839706
TIMM50JMJD40.669398303
TIMM50HAUS80.667994605
TIMM50LRWD10.667072303
TIMM50MTX10.666662404

For details and further investigation, click here