SLC6A17

 

Full name: solute carrier family 6 member 17 Alias Symbol: 
Type: protein-coding gene Cytoband: 1p13.3
Entrez ID: 388662 HGNC ID: HGNC:31399 Ensembl Gene: ENSG00000197106 OMIM ID: 610299
Drug and gene relationship at DGIdb

 

Expression of SLC6A17:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC6A17 388662 233287_at -0.0456 0.9063
GSE26886 SLC6A17 388662 229925_at 0.0536 0.5592
GSE45670 SLC6A17 388662 233287_at 0.0260 0.8104
GSE53622 SLC6A17 388662 99856 -0.6370 0.0002
GSE53624 SLC6A17 388662 99856 -0.3569 0.0016
GSE63941 SLC6A17 388662 233287_at 0.1664 0.2772
GSE77861 SLC6A17 388662 229925_at -0.0333 0.7721
SRP133303 SLC6A17 388662 RNAseq -0.0201 0.9236
SRP159526 SLC6A17 388662 RNAseq -0.0415 0.9326
SRP219564 SLC6A17 388662 RNAseq 2.1164 0.0069
TCGA SLC6A17 388662 RNAseq -0.3681 0.3620

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by SLC6A17 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SLC6A17:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC6A17 388662 0 11 19
GSE20123 SLC6A17 388662 0 11 19
GSE43470 SLC6A17 388662 0 9 34
GSE46452 SLC6A17 388662 2 1 56
GSE47630 SLC6A17 388662 9 5 26
GSE54993 SLC6A17 388662 0 1 69
GSE54994 SLC6A17 388662 7 4 42
GSE60625 SLC6A17 388662 0 0 11
GSE74703 SLC6A17 388662 0 7 29
GSE74704 SLC6A17 388662 0 7 13
TCGA SLC6A17 388662 9 27 60

Total number of gains: 27; Total number of losses: 83; Total Number of normals: 378.  


 

Somatic mutations of SLC6A17:

 

Generating mutation plots.

 

Highly correlated genes for SLC6A17:

 

Showing top 20/27 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC6A17TAGAP0.69007303
SLC6A17AQP80.652351303
SLC6A17PROP10.649862303
SLC6A17G6PC20.645581303
SLC6A17PACS20.636509303
SLC6A17LINC006610.635023303
SLC6A17TNFRSF13C0.625886303
SLC6A17OR5P30.620775303
SLC6A17FHAD10.605782303
SLC6A17TMPRSS60.596169303
SLC6A17INSL30.595384403
SLC6A17SIGLEC10.590956303
SLC6A17PRM10.589533404
SLC6A17C14orf1800.588769303
SLC6A17GAP430.587925303
SLC6A17CCL250.576228403
SLC6A17DNAAF10.572758403
SLC6A17PTGIR0.571432303
SLC6A17KCNK40.571094303
SLC6A17TEKT10.56408303

For details and further investigation, click here