| Full name: solute carrier organic anion transporter family member 2A1 | Alias Symbol: PGT|OATP2A1 | ||
| Type: protein-coding gene | Cytoband: 3q22.1-q22.2 | ||
| Entrez ID: 6578 | HGNC ID: HGNC:10955 | Ensembl Gene: ENSG00000174640 | OMIM ID: 601460 |
| Drug and gene relationship at DGIdb | |||
Expression of SLCO2A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLCO2A1 | 6578 | 204368_at | -0.6032 | 0.2929 | |
| GSE20347 | SLCO2A1 | 6578 | 204368_at | -0.7730 | 0.0018 | |
| GSE23400 | SLCO2A1 | 6578 | 204368_at | -0.2651 | 0.0200 | |
| GSE26886 | SLCO2A1 | 6578 | 204368_at | -0.2891 | 0.4255 | |
| GSE29001 | SLCO2A1 | 6578 | 204368_at | -0.5572 | 0.2789 | |
| GSE38129 | SLCO2A1 | 6578 | 204368_at | -0.7766 | 0.0003 | |
| GSE45670 | SLCO2A1 | 6578 | 204368_at | -0.8288 | 0.0025 | |
| GSE53622 | SLCO2A1 | 6578 | 131857 | -1.5183 | 0.0000 | |
| GSE53624 | SLCO2A1 | 6578 | 131857 | -1.8009 | 0.0000 | |
| GSE63941 | SLCO2A1 | 6578 | 204368_at | 0.6607 | 0.1848 | |
| GSE77861 | SLCO2A1 | 6578 | 204368_at | -0.3172 | 0.4395 | |
| GSE97050 | SLCO2A1 | 6578 | A_23_P135990 | 0.2095 | 0.6553 | |
| SRP007169 | SLCO2A1 | 6578 | RNAseq | -0.7766 | 0.2594 | |
| SRP008496 | SLCO2A1 | 6578 | RNAseq | 0.1259 | 0.8246 | |
| SRP064894 | SLCO2A1 | 6578 | RNAseq | -0.4505 | 0.1494 | |
| SRP133303 | SLCO2A1 | 6578 | RNAseq | -0.5699 | 0.0298 | |
| SRP159526 | SLCO2A1 | 6578 | RNAseq | -0.2213 | 0.6068 | |
| SRP193095 | SLCO2A1 | 6578 | RNAseq | -0.5530 | 0.0388 | |
| SRP219564 | SLCO2A1 | 6578 | RNAseq | -0.3653 | 0.5018 | |
| TCGA | SLCO2A1 | 6578 | RNAseq | -0.4938 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SLCO2A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLCO2A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLCO2A1 | 6578 | 16 | 0 | 14 | |
| GSE20123 | SLCO2A1 | 6578 | 16 | 0 | 14 | |
| GSE43470 | SLCO2A1 | 6578 | 21 | 0 | 22 | |
| GSE46452 | SLCO2A1 | 6578 | 15 | 4 | 40 | |
| GSE47630 | SLCO2A1 | 6578 | 18 | 3 | 19 | |
| GSE54993 | SLCO2A1 | 6578 | 2 | 8 | 60 | |
| GSE54994 | SLCO2A1 | 6578 | 32 | 1 | 20 | |
| GSE60625 | SLCO2A1 | 6578 | 0 | 6 | 5 | |
| GSE74703 | SLCO2A1 | 6578 | 18 | 0 | 18 | |
| GSE74704 | SLCO2A1 | 6578 | 11 | 0 | 9 | |
| TCGA | SLCO2A1 | 6578 | 59 | 5 | 32 |
Total number of gains: 208; Total number of losses: 27; Total Number of normals: 253.
Somatic mutations of SLCO2A1:
Generating mutation plots.
Highly correlated genes for SLCO2A1:
Showing top 20/795 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLCO2A1 | KALRN | 0.761316 | 4 | 0 | 4 |
| SLCO2A1 | GRPEL2 | 0.749214 | 3 | 0 | 3 |
| SLCO2A1 | FAM214A | 0.734966 | 3 | 0 | 3 |
| SLCO2A1 | RAB4B | 0.730913 | 3 | 0 | 3 |
| SLCO2A1 | IRAK3 | 0.714004 | 3 | 0 | 3 |
| SLCO2A1 | PTPN22 | 0.71008 | 3 | 0 | 3 |
| SLCO2A1 | KRT71 | 0.708951 | 3 | 0 | 3 |
| SLCO2A1 | CCNDBP1 | 0.708606 | 4 | 0 | 4 |
| SLCO2A1 | SIT1 | 0.707465 | 3 | 0 | 3 |
| SLCO2A1 | HECA | 0.706261 | 3 | 0 | 3 |
| SLCO2A1 | GPIHBP1 | 0.704533 | 3 | 0 | 3 |
| SLCO2A1 | CRISP3 | 0.7045 | 4 | 0 | 4 |
| SLCO2A1 | TMEM139 | 0.702119 | 3 | 0 | 3 |
| SLCO2A1 | OSTF1 | 0.69974 | 3 | 0 | 3 |
| SLCO2A1 | PLXNA2 | 0.697758 | 3 | 0 | 3 |
| SLCO2A1 | ZCCHC24 | 0.695377 | 3 | 0 | 3 |
| SLCO2A1 | TXNL1 | 0.693339 | 3 | 0 | 3 |
| SLCO2A1 | EMCN | 0.692745 | 5 | 0 | 4 |
| SLCO2A1 | APOBEC1 | 0.692427 | 3 | 0 | 3 |
| SLCO2A1 | CLPS | 0.691985 | 3 | 0 | 3 |
For details and further investigation, click here
