| Full name: keratin 71 | Alias Symbol: KRT6IRS|KRT6IRS1|K6IRS1 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 112802 | HGNC ID: HGNC:28927 | Ensembl Gene: ENSG00000139648 | OMIM ID: 608245 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT71:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT71 | 112802 | 231461_at | -0.0862 | 0.7395 | |
| GSE26886 | KRT71 | 112802 | 231461_at | -0.0340 | 0.7596 | |
| GSE45670 | KRT71 | 112802 | 231461_at | -0.0211 | 0.8404 | |
| GSE63941 | KRT71 | 112802 | 231461_at | 0.0796 | 0.7059 | |
| GSE77861 | KRT71 | 112802 | 231461_at | -0.0975 | 0.3999 | |
| GSE97050 | KRT71 | 112802 | A_23_P99044 | 0.0331 | 0.9165 | |
| TCGA | KRT71 | 112802 | RNAseq | 1.5207 | 0.0924 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRT71 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KRT71:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT71 | 112802 | 8 | 1 | 21 | |
| GSE20123 | KRT71 | 112802 | 8 | 1 | 21 | |
| GSE43470 | KRT71 | 112802 | 3 | 0 | 40 | |
| GSE46452 | KRT71 | 112802 | 7 | 1 | 51 | |
| GSE47630 | KRT71 | 112802 | 10 | 2 | 28 | |
| GSE54993 | KRT71 | 112802 | 0 | 5 | 65 | |
| GSE54994 | KRT71 | 112802 | 5 | 1 | 47 | |
| GSE60625 | KRT71 | 112802 | 0 | 0 | 11 | |
| GSE74703 | KRT71 | 112802 | 3 | 0 | 33 | |
| GSE74704 | KRT71 | 112802 | 5 | 1 | 14 | |
| TCGA | KRT71 | 112802 | 13 | 11 | 72 |
Total number of gains: 62; Total number of losses: 23; Total Number of normals: 403.
Somatic mutations of KRT71:
Generating mutation plots.
Highly correlated genes for KRT71:
Showing top 20/60 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT71 | DIRC1 | 0.790923 | 3 | 0 | 3 |
| KRT71 | PZP | 0.786814 | 3 | 0 | 3 |
| KRT71 | MAPK12 | 0.720262 | 4 | 0 | 4 |
| KRT71 | SLCO2A1 | 0.708951 | 3 | 0 | 3 |
| KRT71 | WNT6 | 0.707039 | 3 | 0 | 3 |
| KRT71 | BAGE | 0.700534 | 3 | 0 | 3 |
| KRT71 | CNTNAP1 | 0.678884 | 3 | 0 | 3 |
| KRT71 | RABEP2 | 0.678446 | 3 | 0 | 3 |
| KRT71 | CAV3 | 0.669588 | 4 | 0 | 3 |
| KRT71 | OR6A2 | 0.668798 | 3 | 0 | 3 |
| KRT71 | TMED5 | 0.667345 | 3 | 0 | 3 |
| KRT71 | KLHL11 | 0.66591 | 3 | 0 | 3 |
| KRT71 | KCNN1 | 0.662492 | 3 | 0 | 3 |
| KRT71 | CYYR1 | 0.654274 | 3 | 0 | 3 |
| KRT71 | DERA | 0.643541 | 3 | 0 | 3 |
| KRT71 | TMEM106A | 0.639035 | 3 | 0 | 3 |
| KRT71 | SPRY1 | 0.637834 | 3 | 0 | 3 |
| KRT71 | PHLDB1 | 0.637314 | 4 | 0 | 3 |
| KRT71 | RNF208 | 0.63572 | 3 | 0 | 3 |
| KRT71 | CLK3 | 0.634358 | 3 | 0 | 3 |
For details and further investigation, click here
