| Full name: SLIT and NTRK like family member 1 | Alias Symbol: KIAA1910 | ||
| Type: protein-coding gene | Cytoband: 13q31.1 | ||
| Entrez ID: 114798 | HGNC ID: HGNC:20297 | Ensembl Gene: ENSG00000178235 | OMIM ID: 609678 |
| Drug and gene relationship at DGIdb | |||
Expression of SLITRK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLITRK1 | 114798 | 236734_at | -0.1481 | 0.6259 | |
| GSE26886 | SLITRK1 | 114798 | 236734_at | 0.0087 | 0.9533 | |
| GSE45670 | SLITRK1 | 114798 | 236734_at | 0.0614 | 0.5262 | |
| GSE53622 | SLITRK1 | 114798 | 17585 | -0.5919 | 0.0000 | |
| GSE53624 | SLITRK1 | 114798 | 17585 | -0.2979 | 0.0085 | |
| GSE63941 | SLITRK1 | 114798 | 236734_at | -0.0635 | 0.7054 | |
| GSE77861 | SLITRK1 | 114798 | 236734_at | 0.0743 | 0.5098 | |
| GSE97050 | SLITRK1 | 114798 | A_32_P136351 | 0.6570 | 0.1474 | |
| TCGA | SLITRK1 | 114798 | RNAseq | -0.7329 | 0.5499 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLITRK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLITRK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLITRK1 | 114798 | 3 | 11 | 16 | |
| GSE20123 | SLITRK1 | 114798 | 3 | 10 | 17 | |
| GSE43470 | SLITRK1 | 114798 | 2 | 11 | 30 | |
| GSE46452 | SLITRK1 | 114798 | 0 | 32 | 27 | |
| GSE47630 | SLITRK1 | 114798 | 3 | 27 | 10 | |
| GSE54993 | SLITRK1 | 114798 | 11 | 3 | 56 | |
| GSE54994 | SLITRK1 | 114798 | 3 | 15 | 35 | |
| GSE60625 | SLITRK1 | 114798 | 0 | 3 | 8 | |
| GSE74703 | SLITRK1 | 114798 | 1 | 9 | 26 | |
| GSE74704 | SLITRK1 | 114798 | 1 | 9 | 10 | |
| TCGA | SLITRK1 | 114798 | 11 | 34 | 51 |
Total number of gains: 38; Total number of losses: 164; Total Number of normals: 286.
Somatic mutations of SLITRK1:
Generating mutation plots.
Highly correlated genes for SLITRK1:
Showing top 20/29 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLITRK1 | CRYGC | 0.681873 | 3 | 0 | 3 |
| SLITRK1 | ENDOG | 0.668521 | 3 | 0 | 3 |
| SLITRK1 | PTCRA | 0.665223 | 3 | 0 | 3 |
| SLITRK1 | CACNA1A | 0.628702 | 3 | 0 | 3 |
| SLITRK1 | NOX5 | 0.619658 | 3 | 0 | 3 |
| SLITRK1 | NKAIN3 | 0.608489 | 3 | 0 | 3 |
| SLITRK1 | TNFSF11 | 0.604308 | 4 | 0 | 3 |
| SLITRK1 | ELF3 | 0.602455 | 4 | 0 | 3 |
| SLITRK1 | WNT1 | 0.601195 | 3 | 0 | 3 |
| SLITRK1 | RALYL | 0.59508 | 3 | 0 | 3 |
| SLITRK1 | CASP12 | 0.595015 | 3 | 0 | 3 |
| SLITRK1 | MAMLD1 | 0.586042 | 3 | 0 | 3 |
| SLITRK1 | GFRA2 | 0.57329 | 3 | 0 | 3 |
| SLITRK1 | FASTK | 0.567293 | 3 | 0 | 3 |
| SLITRK1 | GATA2 | 0.567031 | 3 | 0 | 3 |
| SLITRK1 | RGMB-AS1 | 0.558115 | 4 | 0 | 3 |
| SLITRK1 | FAM9C | 0.556 | 3 | 0 | 3 |
| SLITRK1 | CLDN4 | 0.555674 | 5 | 0 | 3 |
| SLITRK1 | GRIK3 | 0.550147 | 4 | 0 | 3 |
| SLITRK1 | LRRC46 | 0.54904 | 6 | 0 | 4 |
For details and further investigation, click here
