| Full name: small integral membrane protein 1 (Vel blood group) | Alias Symbol: Vel | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 388588 | HGNC ID: HGNC:44204 | Ensembl Gene: ENSG00000235169 | OMIM ID: 615242 |
| Drug and gene relationship at DGIdb | |||
Expression of SMIM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMIM1 | 388588 | 230840_at | 0.0013 | 0.9982 | |
| GSE26886 | SMIM1 | 388588 | 230840_at | 0.2120 | 0.0905 | |
| GSE45670 | SMIM1 | 388588 | 230840_at | -0.1204 | 0.2487 | |
| GSE53622 | SMIM1 | 388588 | 99016 | -0.1400 | 0.3718 | |
| GSE53624 | SMIM1 | 388588 | 99016 | 0.2690 | 0.0217 | |
| GSE63941 | SMIM1 | 388588 | 230840_at | -0.2789 | 0.5027 | |
| GSE77861 | SMIM1 | 388588 | 230840_at | -0.1696 | 0.2683 | |
| SRP133303 | SMIM1 | 388588 | RNAseq | -1.0732 | 0.0020 | |
| SRP159526 | SMIM1 | 388588 | RNAseq | 1.0312 | 0.1500 | |
| SRP219564 | SMIM1 | 388588 | RNAseq | -0.3358 | 0.5441 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SMIM1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SMIM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMIM1 | 388588 | 4 | 6 | 20 | |
| GSE20123 | SMIM1 | 388588 | 4 | 5 | 21 | |
| GSE43470 | SMIM1 | 388588 | 3 | 5 | 35 | |
| GSE46452 | SMIM1 | 388588 | 7 | 1 | 51 | |
| GSE47630 | SMIM1 | 388588 | 8 | 4 | 28 | |
| GSE54993 | SMIM1 | 388588 | 3 | 2 | 65 | |
| GSE54994 | SMIM1 | 388588 | 14 | 3 | 36 | |
| GSE60625 | SMIM1 | 388588 | 0 | 0 | 11 | |
| GSE74703 | SMIM1 | 388588 | 3 | 3 | 30 | |
| GSE74704 | SMIM1 | 388588 | 4 | 0 | 16 | |
| TCGA | SMIM1 | 388588 | 14 | 20 | 62 |
Total number of gains: 64; Total number of losses: 49; Total Number of normals: 375.
Somatic mutations of SMIM1:
Generating mutation plots.
Highly correlated genes for SMIM1:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMIM1 | GPT | 0.619344 | 3 | 0 | 3 |
| SMIM1 | PKDREJ | 0.614968 | 3 | 0 | 3 |
| SMIM1 | DGKE | 0.610189 | 3 | 0 | 3 |
| SMIM1 | POU6F1 | 0.602283 | 3 | 0 | 3 |
| SMIM1 | PRSS50 | 0.591313 | 3 | 0 | 3 |
| SMIM1 | ZNF444 | 0.57645 | 3 | 0 | 3 |
| SMIM1 | DUSP15 | 0.57546 | 3 | 0 | 3 |
| SMIM1 | DOK1 | 0.566929 | 4 | 0 | 4 |
| SMIM1 | IDUA | 0.5648 | 4 | 0 | 3 |
| SMIM1 | CRELD1 | 0.560381 | 4 | 0 | 3 |
| SMIM1 | LINC01169 | 0.552315 | 3 | 0 | 3 |
| SMIM1 | CLDND2 | 0.549785 | 5 | 0 | 3 |
| SMIM1 | CLUL1 | 0.548829 | 4 | 0 | 3 |
| SMIM1 | NTN3 | 0.547427 | 4 | 0 | 3 |
| SMIM1 | NAGLU | 0.547189 | 3 | 0 | 3 |
| SMIM1 | EFCAB13 | 0.534898 | 5 | 0 | 3 |
| SMIM1 | SLC45A1 | 0.527626 | 4 | 0 | 3 |
| SMIM1 | EVC | 0.524322 | 4 | 0 | 3 |
| SMIM1 | LZTS3 | 0.514769 | 4 | 0 | 3 |
| SMIM1 | CYP27A1 | 0.513485 | 5 | 0 | 3 |
For details and further investigation, click here
