| Full name: small nucleolar RNA, H/ACA box 21 | Alias Symbol: ACA21 | ||
| Type: non-coding RNA | Cytoband: 17q12 | ||
| Entrez ID: 619505 | HGNC ID: HGNC:32611 | Ensembl Gene: ENSG00000199293 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SNORA21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNORA21 | 619505 | 215224_at | 1.1204 | 0.2143 | |
| GSE20347 | SNORA21 | 619505 | 215224_at | 0.4596 | 0.0210 | |
| GSE23400 | SNORA21 | 619505 | 215224_at | 0.2632 | 0.0000 | |
| GSE26886 | SNORA21 | 619505 | 215224_at | -0.6984 | 0.0329 | |
| GSE29001 | SNORA21 | 619505 | 215224_at | 0.4524 | 0.0433 | |
| GSE38129 | SNORA21 | 619505 | 215224_at | 0.5791 | 0.0013 | |
| GSE45670 | SNORA21 | 619505 | 215224_at | 0.9200 | 0.0071 | |
| GSE63941 | SNORA21 | 619505 | 215224_at | 0.6486 | 0.1861 | |
| GSE77861 | SNORA21 | 619505 | 215224_at | 0.3171 | 0.2038 | |
| SRP007169 | SNORA21 | 619505 | RNAseq | -0.4164 | 0.5768 | |
| SRP008496 | SNORA21 | 619505 | RNAseq | -0.7181 | 0.4473 | |
| TCGA | SNORA21 | 619505 | RNAseq | 0.6361 | 0.5603 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNORA21 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SNORA21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNORA21 | 619505 | 7 | 1 | 22 | |
| GSE20123 | SNORA21 | 619505 | 7 | 1 | 22 | |
| GSE43470 | SNORA21 | 619505 | 1 | 1 | 41 | |
| GSE46452 | SNORA21 | 619505 | 34 | 0 | 25 | |
| GSE47630 | SNORA21 | 619505 | 8 | 1 | 31 | |
| GSE54993 | SNORA21 | 619505 | 3 | 4 | 63 | |
| GSE54994 | SNORA21 | 619505 | 8 | 5 | 40 | |
| GSE60625 | SNORA21 | 619505 | 4 | 0 | 7 | |
| GSE74703 | SNORA21 | 619505 | 1 | 0 | 35 | |
| GSE74704 | SNORA21 | 619505 | 4 | 1 | 15 | |
| TCGA | SNORA21|ENSG00000199293.1 | NA | 19 | 8 | 69 |
Total number of gains: 96; Total number of losses: 22; Total Number of normals: 370.
Somatic mutations of SNORA21:
Generating mutation plots.
Highly correlated genes for SNORA21:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNORA21 | NUFIP2 | 0.735732 | 4 | 0 | 3 |
| SNORA21 | RUSC1-AS1 | 0.717785 | 3 | 0 | 3 |
| SNORA21 | SPRTN | 0.684461 | 3 | 0 | 3 |
| SNORA21 | WDR75 | 0.681988 | 4 | 0 | 3 |
| SNORA21 | TMEM237 | 0.679635 | 3 | 0 | 3 |
| SNORA21 | TLCD1 | 0.659181 | 3 | 0 | 3 |
| SNORA21 | SMKR1 | 0.655105 | 3 | 0 | 3 |
| SNORA21 | TRAF4 | 0.652263 | 4 | 0 | 3 |
| SNORA21 | RBM12B | 0.649877 | 5 | 0 | 5 |
| SNORA21 | LIN9 | 0.646389 | 3 | 0 | 3 |
| SNORA21 | DOHH | 0.643565 | 3 | 0 | 3 |
| SNORA21 | DHX33 | 0.642909 | 4 | 0 | 3 |
| SNORA21 | TCERG1 | 0.632881 | 4 | 0 | 3 |
| SNORA21 | SS18L1 | 0.630061 | 4 | 0 | 3 |
| SNORA21 | NOP58 | 0.628623 | 4 | 0 | 4 |
| SNORA21 | NBEAL1 | 0.624664 | 4 | 0 | 3 |
| SNORA21 | COA6 | 0.623775 | 4 | 0 | 4 |
| SNORA21 | GRPEL1 | 0.621233 | 3 | 0 | 3 |
| SNORA21 | TMEM138 | 0.61947 | 3 | 0 | 3 |
| SNORA21 | PTPN4 | 0.619333 | 4 | 0 | 3 |
For details and further investigation, click here
