| Full name: SprT-like N-terminal domain | Alias Symbol: DKFZP547N043|Spartan|DVC1 | ||
| Type: protein-coding gene | Cytoband: 1q42.2 | ||
| Entrez ID: 83932 | HGNC ID: HGNC:25356 | Ensembl Gene: ENSG00000010072 | OMIM ID: 616086 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SPRTN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRTN | 83932 | 223511_at | 0.8279 | 0.0962 | |
| GSE26886 | SPRTN | 83932 | 223511_at | -0.1268 | 0.6957 | |
| GSE45670 | SPRTN | 83932 | 223511_at | 0.5333 | 0.0045 | |
| GSE53622 | SPRTN | 83932 | 94701 | 0.4530 | 0.0000 | |
| GSE53624 | SPRTN | 83932 | 94701 | 0.6575 | 0.0000 | |
| GSE63941 | SPRTN | 83932 | 223511_at | 0.0000 | 1.0000 | |
| GSE77861 | SPRTN | 83932 | 223511_at | 0.2772 | 0.2874 | |
| SRP007169 | SPRTN | 83932 | RNAseq | 0.1710 | 0.6825 | |
| SRP008496 | SPRTN | 83932 | RNAseq | 0.4655 | 0.1913 | |
| SRP064894 | SPRTN | 83932 | RNAseq | -0.0749 | 0.7364 | |
| SRP133303 | SPRTN | 83932 | RNAseq | 0.3279 | 0.0290 | |
| SRP159526 | SPRTN | 83932 | RNAseq | 0.2287 | 0.5542 | |
| SRP193095 | SPRTN | 83932 | RNAseq | 0.1336 | 0.2381 | |
| SRP219564 | SPRTN | 83932 | RNAseq | -0.1785 | 0.5699 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPRTN expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SPRTN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRTN | 83932 | 12 | 0 | 18 | |
| GSE20123 | SPRTN | 83932 | 12 | 0 | 18 | |
| GSE43470 | SPRTN | 83932 | 8 | 1 | 34 | |
| GSE46452 | SPRTN | 83932 | 4 | 2 | 53 | |
| GSE47630 | SPRTN | 83932 | 15 | 0 | 25 | |
| GSE54993 | SPRTN | 83932 | 0 | 6 | 64 | |
| GSE54994 | SPRTN | 83932 | 17 | 0 | 36 | |
| GSE60625 | SPRTN | 83932 | 0 | 0 | 11 | |
| GSE74703 | SPRTN | 83932 | 8 | 1 | 27 | |
| GSE74704 | SPRTN | 83932 | 6 | 0 | 14 | |
| TCGA | SPRTN | 83932 | 45 | 3 | 48 |
Total number of gains: 127; Total number of losses: 13; Total Number of normals: 348.
Somatic mutations of SPRTN:
Generating mutation plots.
Highly correlated genes for SPRTN:
Showing top 20/376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRTN | CCDC86 | 0.727889 | 3 | 0 | 3 |
| SPRTN | HEATR1 | 0.722889 | 5 | 0 | 5 |
| SPRTN | INTS7 | 0.698719 | 5 | 0 | 5 |
| SPRTN | SNORA21 | 0.684461 | 3 | 0 | 3 |
| SPRTN | RRP15 | 0.684414 | 5 | 0 | 5 |
| SPRTN | NCBP1 | 0.663052 | 3 | 0 | 3 |
| SPRTN | PRRC2C | 0.662016 | 4 | 0 | 4 |
| SPRTN | MDN1 | 0.661028 | 3 | 0 | 3 |
| SPRTN | EXO1 | 0.655826 | 5 | 0 | 5 |
| SPRTN | LIMK1 | 0.652873 | 3 | 0 | 3 |
| SPRTN | FEN1 | 0.652163 | 3 | 0 | 3 |
| SPRTN | MCM4 | 0.651094 | 4 | 0 | 4 |
| SPRTN | NUF2 | 0.647638 | 5 | 0 | 4 |
| SPRTN | ZNF607 | 0.645566 | 4 | 0 | 3 |
| SPRTN | YEATS2 | 0.643767 | 3 | 0 | 3 |
| SPRTN | XPO5 | 0.640935 | 5 | 0 | 5 |
| SPRTN | KIF14 | 0.640489 | 5 | 0 | 4 |
| SPRTN | FIGNL1 | 0.640469 | 4 | 0 | 4 |
| SPRTN | ASPM | 0.640429 | 5 | 0 | 5 |
| SPRTN | PUS1 | 0.639286 | 4 | 0 | 3 |
For details and further investigation, click here
