| Full name: sorting nexin 33 | Alias Symbol: MGC32065|SH3PXD3C|SNX30 | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 257364 | HGNC ID: HGNC:28468 | Ensembl Gene: ENSG00000173548 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SNX33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX33 | 257364 | 227151_at | -0.3190 | 0.4682 | |
| GSE26886 | SNX33 | 257364 | 227151_at | -0.8734 | 0.0003 | |
| GSE45670 | SNX33 | 257364 | 229898_at | -0.1715 | 0.2070 | |
| GSE53622 | SNX33 | 257364 | 61054 | -0.5844 | 0.0000 | |
| GSE53624 | SNX33 | 257364 | 61054 | -0.6985 | 0.0000 | |
| GSE63941 | SNX33 | 257364 | 227151_at | -0.6144 | 0.0926 | |
| GSE77861 | SNX33 | 257364 | 229898_at | -0.0604 | 0.7335 | |
| GSE97050 | SNX33 | 257364 | A_23_P254404 | -0.0781 | 0.8074 | |
| SRP007169 | SNX33 | 257364 | RNAseq | -1.8062 | 0.0001 | |
| SRP008496 | SNX33 | 257364 | RNAseq | -1.9310 | 0.0000 | |
| SRP064894 | SNX33 | 257364 | RNAseq | -0.7673 | 0.0000 | |
| SRP133303 | SNX33 | 257364 | RNAseq | -0.6098 | 0.0043 | |
| SRP159526 | SNX33 | 257364 | RNAseq | -1.0396 | 0.0001 | |
| SRP193095 | SNX33 | 257364 | RNAseq | -0.7452 | 0.0000 | |
| SRP219564 | SNX33 | 257364 | RNAseq | -0.8994 | 0.0207 | |
| TCGA | SNX33 | 257364 | RNAseq | -0.1526 | 0.0104 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SNX33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX33 | 257364 | 8 | 1 | 21 | |
| GSE20123 | SNX33 | 257364 | 8 | 1 | 21 | |
| GSE43470 | SNX33 | 257364 | 4 | 6 | 33 | |
| GSE46452 | SNX33 | 257364 | 3 | 7 | 49 | |
| GSE47630 | SNX33 | 257364 | 8 | 10 | 22 | |
| GSE54993 | SNX33 | 257364 | 5 | 6 | 59 | |
| GSE54994 | SNX33 | 257364 | 5 | 6 | 42 | |
| GSE60625 | SNX33 | 257364 | 4 | 0 | 7 | |
| GSE74703 | SNX33 | 257364 | 4 | 3 | 29 | |
| GSE74704 | SNX33 | 257364 | 4 | 1 | 15 | |
| TCGA | SNX33 | 257364 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 56; Total Number of normals: 365.
Somatic mutations of SNX33:
Generating mutation plots.
Highly correlated genes for SNX33:
Showing top 20/730 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX33 | ABI1 | 0.805622 | 3 | 0 | 3 |
| SNX33 | KCMF1 | 0.778275 | 3 | 0 | 3 |
| SNX33 | PDLIM2 | 0.769964 | 4 | 0 | 4 |
| SNX33 | NLRX1 | 0.768004 | 6 | 0 | 6 |
| SNX33 | QRICH1 | 0.762736 | 3 | 0 | 3 |
| SNX33 | SLC12A6 | 0.761047 | 3 | 0 | 3 |
| SNX33 | GLTP | 0.748692 | 3 | 0 | 3 |
| SNX33 | CCNYL1 | 0.741521 | 4 | 0 | 4 |
| SNX33 | ORMDL2 | 0.739007 | 3 | 0 | 3 |
| SNX33 | CLTB | 0.738629 | 6 | 0 | 6 |
| SNX33 | SPAG16 | 0.734397 | 3 | 0 | 3 |
| SNX33 | ACAA1 | 0.726292 | 3 | 0 | 3 |
| SNX33 | STRN | 0.722337 | 5 | 0 | 5 |
| SNX33 | GNAI3 | 0.718554 | 5 | 0 | 4 |
| SNX33 | RAB11A | 0.717412 | 5 | 0 | 4 |
| SNX33 | DHX32 | 0.712789 | 5 | 0 | 4 |
| SNX33 | CTTNBP2NL | 0.710292 | 5 | 0 | 5 |
| SNX33 | MAP2K3 | 0.709943 | 3 | 0 | 3 |
| SNX33 | THAP2 | 0.709284 | 4 | 0 | 3 |
| SNX33 | TMPRSS11D | 0.70834 | 4 | 0 | 4 |
For details and further investigation, click here
