| Full name: semaphorin 3G | Alias Symbol: FLJ00014|sem2 | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 56920 | HGNC ID: HGNC:30400 | Ensembl Gene: ENSG00000010319 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
SEMA3G involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of SEMA3G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEMA3G | 56920 | 219689_at | -0.6700 | 0.2294 | |
| GSE20347 | SEMA3G | 56920 | 219689_at | 0.0937 | 0.3315 | |
| GSE23400 | SEMA3G | 56920 | 219689_at | -0.1973 | 0.0001 | |
| GSE26886 | SEMA3G | 56920 | 219689_at | 0.1923 | 0.3001 | |
| GSE29001 | SEMA3G | 56920 | 219689_at | -0.0657 | 0.8080 | |
| GSE38129 | SEMA3G | 56920 | 219689_at | -0.6602 | 0.0229 | |
| GSE45670 | SEMA3G | 56920 | 219689_at | -1.4843 | 0.0000 | |
| GSE53622 | SEMA3G | 56920 | 64074 | -1.0229 | 0.0000 | |
| GSE53624 | SEMA3G | 56920 | 64074 | -0.9022 | 0.0000 | |
| GSE63941 | SEMA3G | 56920 | 219689_at | 0.3372 | 0.0240 | |
| GSE77861 | SEMA3G | 56920 | 219689_at | 0.0075 | 0.9537 | |
| GSE97050 | SEMA3G | 56920 | A_23_P6818 | -0.2954 | 0.2705 | |
| SRP064894 | SEMA3G | 56920 | RNAseq | -0.6846 | 0.0822 | |
| SRP133303 | SEMA3G | 56920 | RNAseq | -1.4591 | 0.0000 | |
| SRP159526 | SEMA3G | 56920 | RNAseq | -0.4196 | 0.3621 | |
| SRP193095 | SEMA3G | 56920 | RNAseq | 0.3413 | 0.2811 | |
| SRP219564 | SEMA3G | 56920 | RNAseq | -0.8860 | 0.0734 | |
| TCGA | SEMA3G | 56920 | RNAseq | -0.7901 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SEMA3G expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEMA3G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEMA3G | 56920 | 0 | 18 | 12 | |
| GSE20123 | SEMA3G | 56920 | 0 | 19 | 11 | |
| GSE43470 | SEMA3G | 56920 | 0 | 18 | 25 | |
| GSE46452 | SEMA3G | 56920 | 2 | 17 | 40 | |
| GSE47630 | SEMA3G | 56920 | 1 | 24 | 15 | |
| GSE54993 | SEMA3G | 56920 | 6 | 2 | 62 | |
| GSE54994 | SEMA3G | 56920 | 0 | 33 | 20 | |
| GSE60625 | SEMA3G | 56920 | 5 | 0 | 6 | |
| GSE74703 | SEMA3G | 56920 | 0 | 14 | 22 | |
| GSE74704 | SEMA3G | 56920 | 0 | 12 | 8 | |
| TCGA | SEMA3G | 56920 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 235; Total Number of normals: 239.
Somatic mutations of SEMA3G:
Generating mutation plots.
Highly correlated genes for SEMA3G:
Showing top 20/593 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEMA3G | EBF1 | 0.78022 | 4 | 0 | 4 |
| SEMA3G | NPY1R | 0.760648 | 4 | 0 | 4 |
| SEMA3G | SMOC2 | 0.760019 | 5 | 0 | 5 |
| SEMA3G | ACKR1 | 0.738112 | 7 | 0 | 7 |
| SEMA3G | EMCN | 0.731037 | 5 | 0 | 4 |
| SEMA3G | FAM107A | 0.723372 | 8 | 0 | 8 |
| SEMA3G | CYP21A2 | 0.720782 | 3 | 0 | 3 |
| SEMA3G | ADAMTSL1 | 0.719964 | 5 | 0 | 5 |
| SEMA3G | GPR146 | 0.719419 | 3 | 0 | 3 |
| SEMA3G | SOD3 | 0.719255 | 9 | 0 | 9 |
| SEMA3G | RAI2 | 0.717016 | 8 | 0 | 7 |
| SEMA3G | ITM2A | 0.710592 | 8 | 0 | 8 |
| SEMA3G | NOSTRIN | 0.707947 | 5 | 0 | 5 |
| SEMA3G | TNS1 | 0.707739 | 8 | 0 | 7 |
| SEMA3G | PPP1R14A | 0.707609 | 6 | 0 | 6 |
| SEMA3G | RGS5 | 0.703948 | 7 | 0 | 6 |
| SEMA3G | ATP1A2 | 0.701792 | 7 | 0 | 6 |
| SEMA3G | RELN | 0.700142 | 8 | 0 | 8 |
| SEMA3G | ECSCR | 0.697958 | 5 | 0 | 5 |
| SEMA3G | MYOC | 0.697861 | 7 | 0 | 7 |
For details and further investigation, click here
