| Full name: SRY-box transcription factor 14 | Alias Symbol: SOX28 | ||
| Type: protein-coding gene | Cytoband: 3q22.3 | ||
| Entrez ID: 8403 | HGNC ID: HGNC:11193 | Ensembl Gene: ENSG00000168875 | OMIM ID: 604747 |
| Drug and gene relationship at DGIdb | |||
Expression of SOX14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SOX14 | 8403 | 208574_at | -0.0463 | 0.9140 | |
| GSE20347 | SOX14 | 8403 | 208574_at | -0.0153 | 0.8404 | |
| GSE23400 | SOX14 | 8403 | 208574_at | -0.0267 | 0.3870 | |
| GSE26886 | SOX14 | 8403 | 208574_at | -0.0310 | 0.7855 | |
| GSE29001 | SOX14 | 8403 | 208574_at | -0.1997 | 0.0251 | |
| GSE38129 | SOX14 | 8403 | 208574_at | -0.0376 | 0.6000 | |
| GSE45670 | SOX14 | 8403 | 208574_at | -0.0753 | 0.4002 | |
| GSE53622 | SOX14 | 8403 | 8258 | 0.3830 | 0.1796 | |
| GSE53624 | SOX14 | 8403 | 8258 | -0.0328 | 0.8640 | |
| GSE63941 | SOX14 | 8403 | 208574_at | 0.1577 | 0.3512 | |
| GSE77861 | SOX14 | 8403 | 208574_at | -0.0341 | 0.7774 | |
| TCGA | SOX14 | 8403 | RNAseq | 2.4616 | 0.1651 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SOX14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SOX14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SOX14 | 8403 | 16 | 0 | 14 | |
| GSE20123 | SOX14 | 8403 | 16 | 0 | 14 | |
| GSE43470 | SOX14 | 8403 | 22 | 0 | 21 | |
| GSE46452 | SOX14 | 8403 | 15 | 4 | 40 | |
| GSE47630 | SOX14 | 8403 | 18 | 3 | 19 | |
| GSE54993 | SOX14 | 8403 | 2 | 8 | 60 | |
| GSE54994 | SOX14 | 8403 | 31 | 2 | 20 | |
| GSE60625 | SOX14 | 8403 | 0 | 6 | 5 | |
| GSE74703 | SOX14 | 8403 | 19 | 0 | 17 | |
| GSE74704 | SOX14 | 8403 | 11 | 0 | 9 | |
| TCGA | SOX14 | 8403 | 62 | 4 | 30 |
Total number of gains: 212; Total number of losses: 27; Total Number of normals: 249.
Somatic mutations of SOX14:
Generating mutation plots.
Highly correlated genes for SOX14:
Showing top 20/93 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SOX14 | ASMT | 0.663325 | 3 | 0 | 3 |
| SOX14 | FLT4 | 0.650544 | 3 | 0 | 3 |
| SOX14 | AHDC1 | 0.649692 | 3 | 0 | 3 |
| SOX14 | MOBP | 0.631421 | 4 | 0 | 4 |
| SOX14 | ALOX12 | 0.626154 | 3 | 0 | 3 |
| SOX14 | CES2 | 0.620677 | 3 | 0 | 3 |
| SOX14 | CHRNA6 | 0.617957 | 3 | 0 | 3 |
| SOX14 | FAM131C | 0.608643 | 3 | 0 | 3 |
| SOX14 | TOLLIP | 0.608563 | 3 | 0 | 3 |
| SOX14 | GLTP | 0.608511 | 3 | 0 | 3 |
| SOX14 | MAPKAPK3 | 0.607939 | 3 | 0 | 3 |
| SOX14 | PIK3R5 | 0.607925 | 3 | 0 | 3 |
| SOX14 | KLK13 | 0.603895 | 3 | 0 | 3 |
| SOX14 | CS | 0.600653 | 3 | 0 | 3 |
| SOX14 | NFE2 | 0.597383 | 4 | 0 | 4 |
| SOX14 | DIO2 | 0.590997 | 3 | 0 | 3 |
| SOX14 | TM6SF2 | 0.587915 | 5 | 0 | 4 |
| SOX14 | HPSE | 0.585135 | 3 | 0 | 3 |
| SOX14 | CHP1 | 0.585044 | 3 | 0 | 3 |
| SOX14 | EGFLAM-AS2 | 0.582466 | 3 | 0 | 3 |
For details and further investigation, click here
