TMEM39A

 

Full name: transmembrane protein 39A Alias Symbol: FLJ10902
Type: protein-coding gene Cytoband: 3q13.33
Entrez ID: 55254 HGNC ID: HGNC:25600 Ensembl Gene: ENSG00000176142 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMEM39A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM39A 55254 222690_s_at 0.7579 0.0374
GSE20347 TMEM39A 55254 218615_s_at 0.7296 0.0001
GSE23400 TMEM39A 55254 218615_s_at 0.3436 0.0000
GSE26886 TMEM39A 55254 222690_s_at 0.0185 0.9342
GSE29001 TMEM39A 55254 218615_s_at 0.8491 0.0004
GSE38129 TMEM39A 55254 218615_s_at 0.7591 0.0000
GSE45670 TMEM39A 55254 222690_s_at 0.8016 0.0003
GSE53622 TMEM39A 55254 3108 0.4064 0.0000
GSE53624 TMEM39A 55254 3108 0.6952 0.0000
GSE63941 TMEM39A 55254 222690_s_at -0.1336 0.7835
GSE77861 TMEM39A 55254 222690_s_at 0.4321 0.0806
GSE97050 TMEM39A 55254 A_23_P84334 0.1479 0.4412
SRP007169 TMEM39A 55254 RNAseq 1.2907 0.0003
SRP008496 TMEM39A 55254 RNAseq 1.4646 0.0000
SRP064894 TMEM39A 55254 RNAseq 0.8414 0.0000
SRP133303 TMEM39A 55254 RNAseq 0.8558 0.0000
SRP159526 TMEM39A 55254 RNAseq 0.9368 0.0000
SRP193095 TMEM39A 55254 RNAseq 0.5776 0.0000
SRP219564 TMEM39A 55254 RNAseq 0.8841 0.0002
TCGA TMEM39A 55254 RNAseq 0.0936 0.1109

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by TMEM39A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM39A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM39A 55254 17 0 13
GSE20123 TMEM39A 55254 17 0 13
GSE43470 TMEM39A 55254 21 1 21
GSE46452 TMEM39A 55254 14 5 40
GSE47630 TMEM39A 55254 16 5 19
GSE54993 TMEM39A 55254 2 6 62
GSE54994 TMEM39A 55254 30 4 19
GSE60625 TMEM39A 55254 0 6 5
GSE74703 TMEM39A 55254 17 1 18
GSE74704 TMEM39A 55254 13 0 7
TCGA TMEM39A 55254 52 7 37

Total number of gains: 199; Total number of losses: 35; Total Number of normals: 254.  

 

Somatic mutations of TMEM39A:

 

Generating mutation plots.

 

Highly correlated genes for TMEM39A:

 

Showing top 20/522 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM39ATIMMDC10.716477404
TMEM39AUMPS0.708692909
TMEM39APIK3R40.6811031109
TMEM39ANEK20.669156707
TMEM39ASCG50.666789606
TMEM39AMCM20.6622951109
TMEM39APLEKHG40.655275303
TMEM39AAPMAP0.653337908
TMEM39ACKS1B0.6509791008
TMEM39ARUVBL10.6504251108
TMEM39AHMCES0.650128908
TMEM39ATPX20.648224808
TMEM39ARFC40.6479741008
TMEM39ASOX300.645233303
TMEM39ACXorf560.64326705
TMEM39ALINC011280.642975303
TMEM39ADTD20.640025303
TMEM39AECT20.6394071009
TMEM39ABCL2L120.639103504
TMEM39ATOR3A0.638993908

For details and further investigation, click here