| Full name: dermatan sulfate epimerase | Alias Symbol: DSEPI|DS-Epi1 | ||
| Type: protein-coding gene | Cytoband: 6q22.1 | ||
| Entrez ID: 29940 | HGNC ID: HGNC:21144 | Ensembl Gene: ENSG00000111817 | OMIM ID: 605942 |
| Drug and gene relationship at DGIdb | |||
Expression of DSE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DSE | 29940 | 218854_at | 0.1390 | 0.9204 | |
| GSE20347 | DSE | 29940 | 218854_at | -0.1684 | 0.6332 | |
| GSE23400 | DSE | 29940 | 218854_at | 0.6902 | 0.0000 | |
| GSE26886 | DSE | 29940 | 218854_at | -0.4692 | 0.2750 | |
| GSE29001 | DSE | 29940 | 218854_at | 0.4694 | 0.3171 | |
| GSE38129 | DSE | 29940 | 218854_at | 0.0697 | 0.8040 | |
| GSE45670 | DSE | 29940 | 218854_at | 0.3672 | 0.2141 | |
| GSE53622 | DSE | 29940 | 106173 | 0.5820 | 0.0000 | |
| GSE53624 | DSE | 29940 | 106173 | 0.5346 | 0.0000 | |
| GSE63941 | DSE | 29940 | 218854_at | -2.4361 | 0.0239 | |
| GSE77861 | DSE | 29940 | 218854_at | -0.1866 | 0.6642 | |
| GSE97050 | DSE | 29940 | A_23_P19226 | 0.7150 | 0.1496 | |
| SRP007169 | DSE | 29940 | RNAseq | 0.6631 | 0.0922 | |
| SRP008496 | DSE | 29940 | RNAseq | 0.7457 | 0.0037 | |
| SRP064894 | DSE | 29940 | RNAseq | 0.7093 | 0.0040 | |
| SRP133303 | DSE | 29940 | RNAseq | 0.7125 | 0.0084 | |
| SRP159526 | DSE | 29940 | RNAseq | -0.3995 | 0.0645 | |
| SRP193095 | DSE | 29940 | RNAseq | 0.3788 | 0.0646 | |
| SRP219564 | DSE | 29940 | RNAseq | 0.0649 | 0.9157 | |
| TCGA | DSE | 29940 | RNAseq | 0.3313 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DSE expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DSE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DSE | 29940 | 1 | 4 | 25 | |
| GSE20123 | DSE | 29940 | 1 | 3 | 26 | |
| GSE43470 | DSE | 29940 | 3 | 1 | 39 | |
| GSE46452 | DSE | 29940 | 2 | 11 | 46 | |
| GSE47630 | DSE | 29940 | 9 | 4 | 27 | |
| GSE54993 | DSE | 29940 | 3 | 2 | 65 | |
| GSE54994 | DSE | 29940 | 8 | 8 | 37 | |
| GSE60625 | DSE | 29940 | 0 | 2 | 9 | |
| GSE74703 | DSE | 29940 | 2 | 1 | 33 | |
| GSE74704 | DSE | 29940 | 0 | 1 | 19 | |
| TCGA | DSE | 29940 | 7 | 22 | 67 |
Total number of gains: 36; Total number of losses: 59; Total Number of normals: 393.
Somatic mutations of DSE:
Generating mutation plots.
Highly correlated genes for DSE:
Showing top 20/455 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DSE | PLAT | 0.752833 | 3 | 0 | 3 |
| DSE | COPS3 | 0.739066 | 3 | 0 | 3 |
| DSE | ANKFY1 | 0.720511 | 3 | 0 | 3 |
| DSE | SOX7 | 0.719353 | 3 | 0 | 3 |
| DSE | MAGOHB | 0.713014 | 3 | 0 | 3 |
| DSE | STRAP | 0.711978 | 3 | 0 | 3 |
| DSE | LYSMD3 | 0.708655 | 3 | 0 | 3 |
| DSE | SNX14 | 0.708218 | 3 | 0 | 3 |
| DSE | UBTD2 | 0.705377 | 3 | 0 | 3 |
| DSE | ERCC4 | 0.703302 | 3 | 0 | 3 |
| DSE | HERPUD2 | 0.686773 | 3 | 0 | 3 |
| DSE | TNFRSF10D | 0.683764 | 4 | 0 | 4 |
| DSE | SRPRB | 0.68072 | 3 | 0 | 3 |
| DSE | SUMF2 | 0.679183 | 4 | 0 | 3 |
| DSE | GFM2 | 0.674428 | 4 | 0 | 3 |
| DSE | SNTB2 | 0.668551 | 5 | 0 | 4 |
| DSE | DDX46 | 0.66755 | 4 | 0 | 4 |
| DSE | CFI | 0.667139 | 4 | 0 | 3 |
| DSE | SGPP1 | 0.660217 | 7 | 0 | 6 |
| DSE | SMIM3 | 0.657604 | 5 | 0 | 5 |
For details and further investigation, click here
