| Full name: ubiquitin conjugating enzyme E2 B | Alias Symbol: UBC2|HHR6B|RAD6B | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 7320 | HGNC ID: HGNC:12473 | Ensembl Gene: ENSG00000119048 | OMIM ID: 179095 |
| Drug and gene relationship at DGIdb | |||
Expression of UBE2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2B | 7320 | 202333_s_at | -0.3650 | 0.3107 | |
| GSE20347 | UBE2B | 7320 | 202333_s_at | -0.3598 | 0.0119 | |
| GSE23400 | UBE2B | 7320 | 202333_s_at | -0.6251 | 0.0000 | |
| GSE26886 | UBE2B | 7320 | 228588_s_at | -0.5661 | 0.0370 | |
| GSE29001 | UBE2B | 7320 | 202333_s_at | -0.3400 | 0.2395 | |
| GSE38129 | UBE2B | 7320 | 202333_s_at | -0.3650 | 0.0011 | |
| GSE45670 | UBE2B | 7320 | 202333_s_at | -0.3240 | 0.1089 | |
| GSE53622 | UBE2B | 7320 | 133848 | -0.6360 | 0.0000 | |
| GSE53624 | UBE2B | 7320 | 133848 | -0.5031 | 0.0000 | |
| GSE63941 | UBE2B | 7320 | 202333_s_at | -0.4480 | 0.1502 | |
| GSE77861 | UBE2B | 7320 | 202333_s_at | -0.5519 | 0.0632 | |
| GSE97050 | UBE2B | 7320 | A_23_P167595 | -0.4323 | 0.1782 | |
| SRP007169 | UBE2B | 7320 | RNAseq | -2.0362 | 0.0000 | |
| SRP008496 | UBE2B | 7320 | RNAseq | -1.9094 | 0.0000 | |
| SRP064894 | UBE2B | 7320 | RNAseq | -0.8107 | 0.0000 | |
| SRP133303 | UBE2B | 7320 | RNAseq | -0.1700 | 0.4271 | |
| SRP159526 | UBE2B | 7320 | RNAseq | -0.4867 | 0.1056 | |
| SRP193095 | UBE2B | 7320 | RNAseq | -0.9355 | 0.0000 | |
| SRP219564 | UBE2B | 7320 | RNAseq | -0.8736 | 0.0070 | |
| TCGA | UBE2B | 7320 | RNAseq | -0.0745 | 0.1365 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UBE2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2B | 7320 | 2 | 11 | 17 | |
| GSE20123 | UBE2B | 7320 | 3 | 11 | 16 | |
| GSE43470 | UBE2B | 7320 | 2 | 8 | 33 | |
| GSE46452 | UBE2B | 7320 | 0 | 27 | 32 | |
| GSE47630 | UBE2B | 7320 | 0 | 21 | 19 | |
| GSE54993 | UBE2B | 7320 | 9 | 1 | 60 | |
| GSE54994 | UBE2B | 7320 | 2 | 14 | 37 | |
| GSE60625 | UBE2B | 7320 | 0 | 0 | 11 | |
| GSE74703 | UBE2B | 7320 | 2 | 5 | 29 | |
| GSE74704 | UBE2B | 7320 | 2 | 5 | 13 | |
| TCGA | UBE2B | 7320 | 3 | 36 | 57 |
Total number of gains: 25; Total number of losses: 139; Total Number of normals: 324.
Somatic mutations of UBE2B:
Generating mutation plots.
Highly correlated genes for UBE2B:
Showing top 20/684 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2B | TANC1 | 0.786238 | 3 | 0 | 3 |
| UBE2B | SOX7 | 0.785921 | 3 | 0 | 3 |
| UBE2B | MBNL3 | 0.751463 | 3 | 0 | 3 |
| UBE2B | C16orf72 | 0.737641 | 3 | 0 | 3 |
| UBE2B | EVC2 | 0.729493 | 3 | 0 | 3 |
| UBE2B | FAM174A | 0.719763 | 6 | 0 | 5 |
| UBE2B | PCM1 | 0.707774 | 4 | 0 | 3 |
| UBE2B | SNRNP27 | 0.705665 | 4 | 0 | 4 |
| UBE2B | TBC1D23 | 0.704147 | 4 | 0 | 4 |
| UBE2B | HERC4 | 0.699507 | 3 | 0 | 3 |
| UBE2B | COG6 | 0.69217 | 3 | 0 | 3 |
| UBE2B | SCYL2 | 0.69211 | 5 | 0 | 4 |
| UBE2B | PNRC2 | 0.690797 | 3 | 0 | 3 |
| UBE2B | ANKRD9 | 0.686757 | 3 | 0 | 3 |
| UBE2B | PPP2CA | 0.685012 | 11 | 0 | 10 |
| UBE2B | SVIP | 0.683518 | 4 | 0 | 3 |
| UBE2B | EHBP1 | 0.681768 | 3 | 0 | 3 |
| UBE2B | RAPGEF6 | 0.675866 | 4 | 0 | 4 |
| UBE2B | SAR1B | 0.674586 | 11 | 0 | 10 |
| UBE2B | EIF3M | 0.674013 | 3 | 0 | 3 |
For details and further investigation, click here
