| Full name: upstream transcription factor 1 | Alias Symbol: UEF|MLTFI|bHLHb11 | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 7391 | HGNC ID: HGNC:12593 | Ensembl Gene: ENSG00000158773 | OMIM ID: 191523 |
| Drug and gene relationship at DGIdb | |||
Expression of USF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USF1 | 7391 | 231768_at | 0.2173 | 0.2687 | |
| GSE26886 | USF1 | 7391 | 231768_at | 0.0620 | 0.6353 | |
| GSE45670 | USF1 | 7391 | 231768_at | 0.5248 | 0.0000 | |
| GSE53622 | USF1 | 7391 | 75669 | 0.5311 | 0.0000 | |
| GSE53624 | USF1 | 7391 | 75669 | 0.6219 | 0.0000 | |
| GSE63941 | USF1 | 7391 | 231768_at | -0.5933 | 0.0047 | |
| GSE77861 | USF1 | 7391 | 231768_at | -0.0505 | 0.8128 | |
| GSE97050 | USF1 | 7391 | A_23_P23646 | 0.6451 | 0.1403 | |
| SRP007169 | USF1 | 7391 | RNAseq | 0.0445 | 0.8946 | |
| SRP008496 | USF1 | 7391 | RNAseq | 0.1246 | 0.5905 | |
| SRP064894 | USF1 | 7391 | RNAseq | 0.5885 | 0.0005 | |
| SRP133303 | USF1 | 7391 | RNAseq | 0.2402 | 0.0248 | |
| SRP159526 | USF1 | 7391 | RNAseq | 0.6715 | 0.0271 | |
| SRP193095 | USF1 | 7391 | RNAseq | 0.2682 | 0.0168 | |
| SRP219564 | USF1 | 7391 | RNAseq | 0.6178 | 0.0279 | |
| TCGA | USF1 | 7391 | RNAseq | 0.1023 | 0.0612 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USF1 | 7391 | 10 | 0 | 20 | |
| GSE20123 | USF1 | 7391 | 10 | 0 | 20 | |
| GSE43470 | USF1 | 7391 | 7 | 2 | 34 | |
| GSE46452 | USF1 | 7391 | 2 | 1 | 56 | |
| GSE47630 | USF1 | 7391 | 14 | 0 | 26 | |
| GSE54993 | USF1 | 7391 | 0 | 6 | 64 | |
| GSE54994 | USF1 | 7391 | 16 | 0 | 37 | |
| GSE60625 | USF1 | 7391 | 0 | 0 | 11 | |
| GSE74703 | USF1 | 7391 | 7 | 2 | 27 | |
| GSE74704 | USF1 | 7391 | 4 | 0 | 16 | |
| TCGA | USF1 | 7391 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.
Somatic mutations of USF1:
Generating mutation plots.
Highly correlated genes for USF1:
Showing top 20/637 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USF1 | PYCR2 | 0.777071 | 3 | 0 | 3 |
| USF1 | KPNA6 | 0.764245 | 3 | 0 | 3 |
| USF1 | TRIM35 | 0.760011 | 3 | 0 | 3 |
| USF1 | SCNM1 | 0.756934 | 3 | 0 | 3 |
| USF1 | RBM15B | 0.743236 | 3 | 0 | 3 |
| USF1 | SLC39A3 | 0.73596 | 3 | 0 | 3 |
| USF1 | GPR153 | 0.730719 | 3 | 0 | 3 |
| USF1 | ADSL | 0.725781 | 3 | 0 | 3 |
| USF1 | PFDN2 | 0.723922 | 5 | 0 | 5 |
| USF1 | AGT | 0.723299 | 3 | 0 | 3 |
| USF1 | TMEM181 | 0.720453 | 3 | 0 | 3 |
| USF1 | S100PBP | 0.719393 | 3 | 0 | 3 |
| USF1 | TMEM138 | 0.719164 | 5 | 0 | 5 |
| USF1 | KCNAB2 | 0.71844 | 3 | 0 | 3 |
| USF1 | ZNF689 | 0.717638 | 3 | 0 | 3 |
| USF1 | PIGG | 0.717003 | 3 | 0 | 3 |
| USF1 | SNAP47 | 0.716434 | 3 | 0 | 3 |
| USF1 | GPR137B | 0.716242 | 4 | 0 | 4 |
| USF1 | CBLB | 0.716132 | 3 | 0 | 3 |
| USF1 | MVP | 0.712539 | 3 | 0 | 3 |
For details and further investigation, click here
