| Full name: spermatogenesis associated 4 | Alias Symbol: TSARG2|SPEF1B | ||
| Type: protein-coding gene | Cytoband: 4q34.2 | ||
| Entrez ID: 132851 | HGNC ID: HGNC:17333 | Ensembl Gene: ENSG00000150628 | OMIM ID: 609879 |
| Drug and gene relationship at DGIdb | |||
Expression of SPATA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATA4 | 132851 | 231178_at | -0.0299 | 0.9232 | |
| GSE26886 | SPATA4 | 132851 | 231178_at | -0.1393 | 0.1884 | |
| GSE45670 | SPATA4 | 132851 | 231178_at | 0.0256 | 0.8165 | |
| GSE53622 | SPATA4 | 132851 | 105872 | -1.1406 | 0.0000 | |
| GSE53624 | SPATA4 | 132851 | 105872 | -1.0970 | 0.0000 | |
| GSE63941 | SPATA4 | 132851 | 231178_at | -0.0058 | 0.9750 | |
| GSE77861 | SPATA4 | 132851 | 231178_at | -0.0310 | 0.7740 | |
| TCGA | SPATA4 | 132851 | RNAseq | -1.4295 | 0.2790 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SPATA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPATA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATA4 | 132851 | 1 | 11 | 18 | |
| GSE20123 | SPATA4 | 132851 | 1 | 11 | 18 | |
| GSE43470 | SPATA4 | 132851 | 0 | 14 | 29 | |
| GSE46452 | SPATA4 | 132851 | 1 | 36 | 22 | |
| GSE47630 | SPATA4 | 132851 | 0 | 22 | 18 | |
| GSE54993 | SPATA4 | 132851 | 10 | 0 | 60 | |
| GSE54994 | SPATA4 | 132851 | 2 | 12 | 39 | |
| GSE60625 | SPATA4 | 132851 | 0 | 0 | 11 | |
| GSE74703 | SPATA4 | 132851 | 0 | 12 | 24 | |
| GSE74704 | SPATA4 | 132851 | 0 | 5 | 15 | |
| TCGA | SPATA4 | 132851 | 10 | 36 | 50 |
Total number of gains: 25; Total number of losses: 159; Total Number of normals: 304.
Somatic mutations of SPATA4:
Generating mutation plots.
Highly correlated genes for SPATA4:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATA4 | SUCLG2-AS1 | 0.709698 | 3 | 0 | 3 |
| SPATA4 | CNGA3 | 0.695048 | 3 | 0 | 3 |
| SPATA4 | SH3BGR | 0.656627 | 4 | 0 | 4 |
| SPATA4 | CFL2 | 0.655262 | 3 | 0 | 3 |
| SPATA4 | ARHGAP6 | 0.655095 | 4 | 0 | 4 |
| SPATA4 | ANO5 | 0.65128 | 3 | 0 | 3 |
| SPATA4 | SNTB1 | 0.635114 | 3 | 0 | 3 |
| SPATA4 | SHISA3 | 0.63069 | 3 | 0 | 3 |
| SPATA4 | PGR | 0.628329 | 4 | 0 | 4 |
| SPATA4 | SEMA3E | 0.621801 | 3 | 0 | 3 |
| SPATA4 | NXPH3 | 0.612542 | 4 | 0 | 4 |
| SPATA4 | NCAM1 | 0.61179 | 4 | 0 | 3 |
| SPATA4 | MTURN | 0.608987 | 3 | 0 | 3 |
| SPATA4 | REEP2 | 0.607241 | 4 | 0 | 3 |
| SPATA4 | FAM229B | 0.60606 | 3 | 0 | 3 |
| SPATA4 | SORCS1 | 0.60287 | 3 | 0 | 3 |
| SPATA4 | PDE2A | 0.599686 | 3 | 0 | 3 |
| SPATA4 | FLNC | 0.598003 | 4 | 0 | 3 |
| SPATA4 | DZIP3 | 0.596361 | 3 | 0 | 3 |
| SPATA4 | SNPH | 0.593304 | 4 | 0 | 3 |
For details and further investigation, click here
