| Full name: spermatogenesis associated 7 | Alias Symbol: HSD3 | ||
| Type: protein-coding gene | Cytoband: 14q31.3 | ||
| Entrez ID: 55812 | HGNC ID: HGNC:20423 | Ensembl Gene: | OMIM ID: 609868 |
| Drug and gene relationship at DGIdb | |||
Expression of SPATA7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATA7 | 55812 | 219583_s_at | -0.1474 | 0.8518 | |
| GSE20347 | SPATA7 | 55812 | 219583_s_at | 0.0417 | 0.8650 | |
| GSE23400 | SPATA7 | 55812 | 219583_s_at | 0.0444 | 0.0762 | |
| GSE26886 | SPATA7 | 55812 | 234929_s_at | 0.3725 | 0.0162 | |
| GSE29001 | SPATA7 | 55812 | 219583_s_at | -0.0529 | 0.8775 | |
| GSE38129 | SPATA7 | 55812 | 219583_s_at | -0.1077 | 0.6449 | |
| GSE45670 | SPATA7 | 55812 | 219583_s_at | -0.2261 | 0.4774 | |
| GSE53622 | SPATA7 | 55812 | 96433 | 0.2521 | 0.0489 | |
| GSE53624 | SPATA7 | 55812 | 96433 | 0.2567 | 0.0797 | |
| GSE63941 | SPATA7 | 55812 | 234929_s_at | -0.7201 | 0.1512 | |
| GSE77861 | SPATA7 | 55812 | 234929_s_at | 0.0533 | 0.7303 | |
| GSE97050 | SPATA7 | 55812 | A_33_P3374563 | 0.0003 | 0.9989 | |
| SRP007169 | SPATA7 | 55812 | RNAseq | -0.2676 | 0.5828 | |
| SRP008496 | SPATA7 | 55812 | RNAseq | 0.2149 | 0.5759 | |
| SRP064894 | SPATA7 | 55812 | RNAseq | 0.5640 | 0.0151 | |
| SRP133303 | SPATA7 | 55812 | RNAseq | 0.3752 | 0.1001 | |
| SRP159526 | SPATA7 | 55812 | RNAseq | 0.4461 | 0.3940 | |
| SRP193095 | SPATA7 | 55812 | RNAseq | -0.0284 | 0.8638 | |
| SRP219564 | SPATA7 | 55812 | RNAseq | 0.0245 | 0.9601 | |
| TCGA | SPATA7 | 55812 | RNAseq | -0.2193 | 0.0485 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPATA7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPATA7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATA7 | 55812 | 7 | 4 | 19 | |
| GSE20123 | SPATA7 | 55812 | 7 | 4 | 19 | |
| GSE43470 | SPATA7 | 55812 | 7 | 3 | 33 | |
| GSE46452 | SPATA7 | 55812 | 16 | 3 | 40 | |
| GSE47630 | SPATA7 | 55812 | 11 | 8 | 21 | |
| GSE54993 | SPATA7 | 55812 | 3 | 8 | 59 | |
| GSE54994 | SPATA7 | 55812 | 19 | 4 | 30 | |
| GSE60625 | SPATA7 | 55812 | 0 | 2 | 9 | |
| GSE74703 | SPATA7 | 55812 | 6 | 3 | 27 | |
| GSE74704 | SPATA7 | 55812 | 4 | 4 | 12 | |
| TCGA | SPATA7 | 55812 | 30 | 21 | 45 |
Total number of gains: 110; Total number of losses: 64; Total Number of normals: 314.
Somatic mutations of SPATA7:
Generating mutation plots.
Highly correlated genes for SPATA7:
Showing top 20/414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATA7 | POLR2J | 0.70349 | 3 | 0 | 3 |
| SPATA7 | USP12 | 0.697509 | 3 | 0 | 3 |
| SPATA7 | ZNF70 | 0.683329 | 3 | 0 | 3 |
| SPATA7 | ANKRD46 | 0.683009 | 3 | 0 | 3 |
| SPATA7 | PPP1R9A | 0.66748 | 3 | 0 | 3 |
| SPATA7 | HEXA | 0.664831 | 5 | 0 | 5 |
| SPATA7 | KIAA1586 | 0.664502 | 5 | 0 | 4 |
| SPATA7 | IL17RD | 0.661268 | 3 | 0 | 3 |
| SPATA7 | ZNHIT6 | 0.656552 | 3 | 0 | 3 |
| SPATA7 | MB21D2 | 0.652616 | 3 | 0 | 3 |
| SPATA7 | TM4SF18 | 0.652372 | 3 | 0 | 3 |
| SPATA7 | CBR4 | 0.650293 | 3 | 0 | 3 |
| SPATA7 | ANXA7 | 0.649974 | 3 | 0 | 3 |
| SPATA7 | PURA | 0.648262 | 3 | 0 | 3 |
| SPATA7 | FUBP1 | 0.647198 | 3 | 0 | 3 |
| SPATA7 | SYNJ2BP | 0.646931 | 3 | 0 | 3 |
| SPATA7 | ZNF544 | 0.645123 | 3 | 0 | 3 |
| SPATA7 | SNX13 | 0.643426 | 5 | 0 | 4 |
| SPATA7 | EGFLAM | 0.640244 | 4 | 0 | 3 |
| SPATA7 | CEP57L1 | 0.639443 | 4 | 0 | 3 |
For details and further investigation, click here
