| Full name: single stranded DNA binding protein 2 | Alias Symbol: HSPC116 | ||
| Type: protein-coding gene | Cytoband: 5q14.1 | ||
| Entrez ID: 23635 | HGNC ID: HGNC:15831 | Ensembl Gene: ENSG00000145687 | OMIM ID: 607389 |
| Drug and gene relationship at DGIdb | |||
Expression of SSBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSBP2 | 23635 | 203787_at | -1.1320 | 0.0086 | |
| GSE20347 | SSBP2 | 23635 | 203787_at | -1.3642 | 0.0001 | |
| GSE23400 | SSBP2 | 23635 | 203787_at | -0.5873 | 0.0000 | |
| GSE26886 | SSBP2 | 23635 | 203787_at | -0.5028 | 0.1845 | |
| GSE29001 | SSBP2 | 23635 | 203787_at | -1.5356 | 0.0036 | |
| GSE38129 | SSBP2 | 23635 | 203787_at | -1.2301 | 0.0000 | |
| GSE45670 | SSBP2 | 23635 | 203787_at | -1.2871 | 0.0000 | |
| GSE53622 | SSBP2 | 23635 | 56540 | -1.6207 | 0.0000 | |
| GSE53624 | SSBP2 | 23635 | 56540 | -1.2240 | 0.0000 | |
| GSE63941 | SSBP2 | 23635 | 203787_at | -1.7066 | 0.0538 | |
| GSE77861 | SSBP2 | 23635 | 203787_at | -1.3269 | 0.0130 | |
| GSE97050 | SSBP2 | 23635 | A_23_P33791 | -1.4747 | 0.0599 | |
| SRP007169 | SSBP2 | 23635 | RNAseq | -1.5366 | 0.0071 | |
| SRP008496 | SSBP2 | 23635 | RNAseq | -1.0035 | 0.0108 | |
| SRP064894 | SSBP2 | 23635 | RNAseq | -0.9296 | 0.0005 | |
| SRP133303 | SSBP2 | 23635 | RNAseq | -0.7094 | 0.0002 | |
| SRP159526 | SSBP2 | 23635 | RNAseq | -1.2209 | 0.0001 | |
| SRP193095 | SSBP2 | 23635 | RNAseq | -0.9561 | 0.0000 | |
| SRP219564 | SSBP2 | 23635 | RNAseq | -0.8448 | 0.0579 | |
| TCGA | SSBP2 | 23635 | RNAseq | -0.1609 | 0.0950 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by SSBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SSBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSBP2 | 23635 | 1 | 13 | 16 | |
| GSE20123 | SSBP2 | 23635 | 1 | 13 | 16 | |
| GSE43470 | SSBP2 | 23635 | 2 | 11 | 30 | |
| GSE46452 | SSBP2 | 23635 | 0 | 28 | 31 | |
| GSE47630 | SSBP2 | 23635 | 1 | 19 | 20 | |
| GSE54993 | SSBP2 | 23635 | 8 | 1 | 61 | |
| GSE54994 | SSBP2 | 23635 | 2 | 18 | 33 | |
| GSE60625 | SSBP2 | 23635 | 0 | 0 | 11 | |
| GSE74703 | SSBP2 | 23635 | 1 | 7 | 28 | |
| GSE74704 | SSBP2 | 23635 | 1 | 6 | 13 | |
| TCGA | SSBP2 | 23635 | 5 | 50 | 41 |
Total number of gains: 22; Total number of losses: 166; Total Number of normals: 300.
Somatic mutations of SSBP2:
Generating mutation plots.
Highly correlated genes for SSBP2:
Showing top 20/1448 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSBP2 | CLEC3B | 0.77669 | 3 | 0 | 3 |
| SSBP2 | CYP21A2 | 0.775105 | 3 | 0 | 3 |
| SSBP2 | ADAMTS9-AS2 | 0.773149 | 4 | 0 | 4 |
| SSBP2 | EIF4E3 | 0.762715 | 7 | 0 | 7 |
| SSBP2 | C1QTNF7 | 0.761157 | 5 | 0 | 5 |
| SSBP2 | RGS7BP | 0.753985 | 5 | 0 | 5 |
| SSBP2 | VIT | 0.750106 | 6 | 0 | 6 |
| SSBP2 | MAMDC2 | 0.749493 | 6 | 0 | 6 |
| SSBP2 | ANGPTL1 | 0.740309 | 6 | 0 | 5 |
| SSBP2 | HMHB1 | 0.73582 | 3 | 0 | 3 |
| SSBP2 | FGF14 | 0.733964 | 4 | 0 | 4 |
| SSBP2 | HLF | 0.732564 | 11 | 0 | 10 |
| SSBP2 | PTCHD1 | 0.729542 | 5 | 0 | 5 |
| SSBP2 | RAB9B | 0.716296 | 6 | 0 | 5 |
| SSBP2 | IL6ST | 0.716069 | 11 | 0 | 11 |
| SSBP2 | HOXA3 | 0.713425 | 3 | 0 | 3 |
| SSBP2 | NEGR1 | 0.713199 | 6 | 0 | 5 |
| SSBP2 | SYNPO2 | 0.712152 | 7 | 0 | 7 |
| SSBP2 | RBFOX3 | 0.710628 | 3 | 0 | 3 |
| SSBP2 | CCNG1 | 0.706714 | 11 | 0 | 10 |
For details and further investigation, click here
