PRR5L

 

Full name: proline rich 5 like Alias Symbol: FLJ14213|PROTOR-2
Type: protein-coding gene Cytoband: 11p13-p12
Entrez ID: 79899 HGNC ID: HGNC:25878 Ensembl Gene: ENSG00000135362 OMIM ID: 611728
Drug and gene relationship at DGIdb

 

Expression of PRR5L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRR5L 79899 1555486_a_at 0.7683 0.1144
GSE20347 PRR5L 79899 219383_at 0.4914 0.0065
GSE23400 PRR5L 79899 219383_at 0.1671 0.0000
GSE26886 PRR5L 79899 1555486_a_at 1.5933 0.0000
GSE29001 PRR5L 79899 219383_at 0.3921 0.0341
GSE38129 PRR5L 79899 219383_at 0.7302 0.0000
GSE45670 PRR5L 79899 1555486_a_at 0.9090 0.0022
GSE53622 PRR5L 79899 28202 1.5927 0.0000
GSE53624 PRR5L 79899 28202 1.9667 0.0000
GSE63941 PRR5L 79899 1555486_a_at 0.8367 0.1293
GSE77861 PRR5L 79899 1555486_a_at 0.5993 0.0117
GSE97050 PRR5L 79899 A_23_P116512 0.6243 0.0786
SRP007169 PRR5L 79899 RNAseq 3.3178 0.0000
SRP008496 PRR5L 79899 RNAseq 3.4797 0.0000
SRP064894 PRR5L 79899 RNAseq 2.4134 0.0000
SRP133303 PRR5L 79899 RNAseq 1.7545 0.0000
SRP159526 PRR5L 79899 RNAseq 1.1714 0.0300
SRP193095 PRR5L 79899 RNAseq 1.5522 0.0000
SRP219564 PRR5L 79899 RNAseq 2.9556 0.0000
TCGA PRR5L 79899 RNAseq 0.9860 0.0000

Upregulated datasets: 10; Downregulated datasets: 0.  

 

Survival by PRR5L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PRR5L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRR5L 79899 0 9 21
GSE20123 PRR5L 79899 0 8 22
GSE43470 PRR5L 79899 3 4 36
GSE46452 PRR5L 79899 7 5 47
GSE47630 PRR5L 79899 3 10 27
GSE54993 PRR5L 79899 3 2 65
GSE54994 PRR5L 79899 3 10 40
GSE60625 PRR5L 79899 0 0 11
GSE74703 PRR5L 79899 2 2 32
GSE74704 PRR5L 79899 0 6 14
TCGA PRR5L 79899 13 23 60

Total number of gains: 34; Total number of losses: 79; Total Number of normals: 375.  

 

Somatic mutations of PRR5L:

 

Generating mutation plots.

 

Highly correlated genes for PRR5L:

 

Showing top 20/1808 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRR5LTNFAIP10.816173303
PRR5LCENPL0.749518606
PRR5LKTI120.749116303
PRR5LSPON20.739896303
PRR5LC1orf1310.735196707
PRR5LFAM89A0.732111303
PRR5LLRRC8C0.731193303
PRR5LPYCR20.730662303
PRR5LSHISA20.730304605
PRR5LBRAT10.727737706
PRR5LKDM5A0.726865303
PRR5LZNF4690.723471606
PRR5LPOLRMT0.719362303
PRR5LLRP120.71820611011
PRR5LCTHRC10.714418706
PRR5LRILPL10.714266303
PRR5LCDH110.71266910010
PRR5LLEMD20.709863303
PRR5LGRAMD1A0.708788606
PRR5LOAF0.708598504

For details and further investigation, click here