| Full name: WD repeat and SOCS box containing 2 | Alias Symbol: SBA2|MGC10210 | ||
| Type: protein-coding gene | Cytoband: 12q24.23 | ||
| Entrez ID: 55884 | HGNC ID: HGNC:19222 | Ensembl Gene: ENSG00000176871 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of WSB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WSB2 | 55884 | 201760_s_at | 0.3874 | 0.3824 | |
| GSE20347 | WSB2 | 55884 | 201760_s_at | -0.7408 | 0.0000 | |
| GSE23400 | WSB2 | 55884 | 201760_s_at | -0.3549 | 0.0001 | |
| GSE26886 | WSB2 | 55884 | 201760_s_at | -0.8571 | 0.0000 | |
| GSE29001 | WSB2 | 55884 | 201760_s_at | -0.4755 | 0.1109 | |
| GSE38129 | WSB2 | 55884 | 201760_s_at | -0.3613 | 0.0242 | |
| GSE45670 | WSB2 | 55884 | 201760_s_at | -0.1757 | 0.1787 | |
| GSE53622 | WSB2 | 55884 | 39696 | -0.5623 | 0.0000 | |
| GSE53624 | WSB2 | 55884 | 39696 | -0.5066 | 0.0000 | |
| GSE63941 | WSB2 | 55884 | 201760_s_at | -0.7873 | 0.0515 | |
| GSE77861 | WSB2 | 55884 | 201760_s_at | -0.3608 | 0.0434 | |
| GSE97050 | WSB2 | 55884 | A_23_P259272 | -0.5745 | 0.1552 | |
| SRP007169 | WSB2 | 55884 | RNAseq | -1.7441 | 0.0000 | |
| SRP008496 | WSB2 | 55884 | RNAseq | -1.5018 | 0.0000 | |
| SRP064894 | WSB2 | 55884 | RNAseq | -0.4675 | 0.0022 | |
| SRP133303 | WSB2 | 55884 | RNAseq | -0.4537 | 0.0017 | |
| SRP159526 | WSB2 | 55884 | RNAseq | -0.2569 | 0.1409 | |
| SRP193095 | WSB2 | 55884 | RNAseq | -0.5957 | 0.0000 | |
| SRP219564 | WSB2 | 55884 | RNAseq | -0.8656 | 0.0197 | |
| TCGA | WSB2 | 55884 | RNAseq | -0.1201 | 0.0077 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by WSB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WSB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WSB2 | 55884 | 6 | 2 | 22 | |
| GSE20123 | WSB2 | 55884 | 6 | 2 | 22 | |
| GSE43470 | WSB2 | 55884 | 2 | 0 | 41 | |
| GSE46452 | WSB2 | 55884 | 9 | 1 | 49 | |
| GSE47630 | WSB2 | 55884 | 9 | 3 | 28 | |
| GSE54993 | WSB2 | 55884 | 0 | 5 | 65 | |
| GSE54994 | WSB2 | 55884 | 6 | 6 | 41 | |
| GSE60625 | WSB2 | 55884 | 0 | 0 | 11 | |
| GSE74703 | WSB2 | 55884 | 2 | 0 | 34 | |
| GSE74704 | WSB2 | 55884 | 3 | 2 | 15 | |
| TCGA | WSB2 | 55884 | 21 | 10 | 65 |
Total number of gains: 64; Total number of losses: 31; Total Number of normals: 393.
Somatic mutations of WSB2:
Generating mutation plots.
Highly correlated genes for WSB2:
Showing top 20/848 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WSB2 | ZNF416 | 0.770483 | 4 | 0 | 4 |
| WSB2 | NR2C2 | 0.769816 | 3 | 0 | 3 |
| WSB2 | CHCHD1 | 0.731915 | 3 | 0 | 3 |
| WSB2 | UBR3 | 0.729323 | 3 | 0 | 3 |
| WSB2 | PPP2R3C | 0.729173 | 3 | 0 | 3 |
| WSB2 | LYSMD3 | 0.72724 | 4 | 0 | 4 |
| WSB2 | MLKL | 0.724202 | 3 | 0 | 3 |
| WSB2 | TBC1D14 | 0.7234 | 3 | 0 | 3 |
| WSB2 | CCNDBP1 | 0.722515 | 5 | 0 | 5 |
| WSB2 | EIF2AK4 | 0.716634 | 3 | 0 | 3 |
| WSB2 | ZMPSTE24 | 0.713023 | 4 | 0 | 4 |
| WSB2 | ZNF615 | 0.712689 | 3 | 0 | 3 |
| WSB2 | ZNF823 | 0.708713 | 5 | 0 | 5 |
| WSB2 | PRKAR2A | 0.706467 | 5 | 0 | 5 |
| WSB2 | RWDD4 | 0.706053 | 3 | 0 | 3 |
| WSB2 | PLEKHA7 | 0.705473 | 6 | 0 | 6 |
| WSB2 | STX3 | 0.702861 | 3 | 0 | 3 |
| WSB2 | VPS37B | 0.701867 | 9 | 0 | 8 |
| WSB2 | BRWD3 | 0.701615 | 4 | 0 | 3 |
| WSB2 | C6orf62 | 0.696029 | 6 | 0 | 6 |
For details and further investigation, click here
