| Full name: myotubularin related protein 2 | Alias Symbol: KIAA1073 | ||
| Type: protein-coding gene | Cytoband: 11q21 | ||
| Entrez ID: 8898 | HGNC ID: HGNC:7450 | Ensembl Gene: ENSG00000087053 | OMIM ID: 603557 |
| Drug and gene relationship at DGIdb | |||
Expression of MTMR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTMR2 | 8898 | 203211_s_at | 0.1258 | 0.7040 | |
| GSE20347 | MTMR2 | 8898 | 203211_s_at | 0.0421 | 0.8891 | |
| GSE23400 | MTMR2 | 8898 | 203212_s_at | 0.0749 | 0.2334 | |
| GSE26886 | MTMR2 | 8898 | 203211_s_at | 0.5890 | 0.0078 | |
| GSE29001 | MTMR2 | 8898 | 203212_s_at | -0.2761 | 0.2233 | |
| GSE38129 | MTMR2 | 8898 | 203211_s_at | 0.0920 | 0.5993 | |
| GSE45670 | MTMR2 | 8898 | 203211_s_at | 0.1493 | 0.3374 | |
| GSE53622 | MTMR2 | 8898 | 146388 | 0.0923 | 0.1342 | |
| GSE53624 | MTMR2 | 8898 | 146388 | 0.1900 | 0.0004 | |
| GSE63941 | MTMR2 | 8898 | 203211_s_at | -0.5256 | 0.2818 | |
| GSE77861 | MTMR2 | 8898 | 203211_s_at | 0.0786 | 0.8466 | |
| GSE97050 | MTMR2 | 8898 | A_23_P64019 | -0.3247 | 0.1695 | |
| SRP007169 | MTMR2 | 8898 | RNAseq | 0.0484 | 0.9059 | |
| SRP008496 | MTMR2 | 8898 | RNAseq | 0.3490 | 0.1011 | |
| SRP064894 | MTMR2 | 8898 | RNAseq | 0.2062 | 0.2243 | |
| SRP133303 | MTMR2 | 8898 | RNAseq | 0.1321 | 0.3437 | |
| SRP159526 | MTMR2 | 8898 | RNAseq | 0.2712 | 0.4218 | |
| SRP193095 | MTMR2 | 8898 | RNAseq | -0.1662 | 0.2904 | |
| SRP219564 | MTMR2 | 8898 | RNAseq | -0.0990 | 0.7867 | |
| TCGA | MTMR2 | 8898 | RNAseq | -0.0365 | 0.4621 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MTMR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTMR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTMR2 | 8898 | 3 | 9 | 18 | |
| GSE20123 | MTMR2 | 8898 | 3 | 9 | 18 | |
| GSE43470 | MTMR2 | 8898 | 2 | 6 | 35 | |
| GSE46452 | MTMR2 | 8898 | 5 | 24 | 30 | |
| GSE47630 | MTMR2 | 8898 | 2 | 19 | 19 | |
| GSE54993 | MTMR2 | 8898 | 9 | 2 | 59 | |
| GSE54994 | MTMR2 | 8898 | 6 | 18 | 29 | |
| GSE60625 | MTMR2 | 8898 | 0 | 3 | 8 | |
| GSE74703 | MTMR2 | 8898 | 1 | 5 | 30 | |
| GSE74704 | MTMR2 | 8898 | 3 | 5 | 12 | |
| TCGA | MTMR2 | 8898 | 11 | 42 | 43 |
Total number of gains: 45; Total number of losses: 142; Total Number of normals: 301.
Somatic mutations of MTMR2:
Generating mutation plots.
Highly correlated genes for MTMR2:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTMR2 | TRAPPC6B | 0.746693 | 3 | 0 | 3 |
| MTMR2 | LIN52 | 0.725385 | 3 | 0 | 3 |
| MTMR2 | STYX | 0.719279 | 3 | 0 | 3 |
| MTMR2 | SLC37A3 | 0.710298 | 3 | 0 | 3 |
| MTMR2 | CST5 | 0.701603 | 3 | 0 | 3 |
| MTMR2 | KPNA1 | 0.691451 | 3 | 0 | 3 |
| MTMR2 | IRAK1BP1 | 0.691303 | 3 | 0 | 3 |
| MTMR2 | ZCCHC3 | 0.690432 | 3 | 0 | 3 |
| MTMR2 | ZNF506 | 0.675702 | 3 | 0 | 3 |
| MTMR2 | TRIM35 | 0.673176 | 3 | 0 | 3 |
| MTMR2 | TLK2 | 0.671021 | 3 | 0 | 3 |
| MTMR2 | PPP6R3 | 0.670434 | 3 | 0 | 3 |
| MTMR2 | HYLS1 | 0.666393 | 4 | 0 | 3 |
| MTMR2 | EIF3M | 0.665444 | 3 | 0 | 3 |
| MTMR2 | BTBD7 | 0.664968 | 3 | 0 | 3 |
| MTMR2 | CYCS | 0.657457 | 4 | 0 | 3 |
| MTMR2 | KDSR | 0.656862 | 5 | 0 | 5 |
| MTMR2 | LEPROTL1 | 0.655201 | 3 | 0 | 3 |
| MTMR2 | DNAJC24 | 0.653147 | 4 | 0 | 3 |
| MTMR2 | MASTL | 0.651307 | 4 | 0 | 4 |
For details and further investigation, click here
