| Full name: ATP binding cassette subfamily A member 12 | Alias Symbol: DKFZP434G232|LI2 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 26154 | HGNC ID: HGNC:14637 | Ensembl Gene: ENSG00000144452 | OMIM ID: 607800 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCA12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCA12 | 26154 | 215465_at | 2.2256 | 0.2471 | |
| GSE20347 | ABCA12 | 26154 | 215465_at | 0.6754 | 0.0347 | |
| GSE23400 | ABCA12 | 26154 | 215465_at | 0.3532 | 0.0007 | |
| GSE26886 | ABCA12 | 26154 | 215465_at | 0.6848 | 0.0385 | |
| GSE29001 | ABCA12 | 26154 | 215465_at | 1.1992 | 0.0385 | |
| GSE38129 | ABCA12 | 26154 | 215465_at | 0.9141 | 0.0018 | |
| GSE45670 | ABCA12 | 26154 | 215465_at | 2.6345 | 0.0000 | |
| GSE53622 | ABCA12 | 26154 | 120741 | 1.2871 | 0.0000 | |
| GSE53624 | ABCA12 | 26154 | 120741 | 1.2873 | 0.0000 | |
| GSE63941 | ABCA12 | 26154 | 215465_at | 1.7080 | 0.1700 | |
| GSE77861 | ABCA12 | 26154 | 215465_at | 0.8442 | 0.0858 | |
| GSE97050 | ABCA12 | 26154 | A_33_P3367984 | 1.1354 | 0.2049 | |
| SRP007169 | ABCA12 | 26154 | RNAseq | 1.2277 | 0.0212 | |
| SRP008496 | ABCA12 | 26154 | RNAseq | 1.5206 | 0.0020 | |
| SRP133303 | ABCA12 | 26154 | RNAseq | 2.2389 | 0.0000 | |
| SRP159526 | ABCA12 | 26154 | RNAseq | 2.3463 | 0.0057 | |
| SRP193095 | ABCA12 | 26154 | RNAseq | 1.8098 | 0.0000 | |
| SRP219564 | ABCA12 | 26154 | RNAseq | 1.1403 | 0.3531 | |
| TCGA | ABCA12 | 26154 | RNAseq | 1.6450 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by ABCA12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCA12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCA12 | 26154 | 1 | 13 | 16 | |
| GSE20123 | ABCA12 | 26154 | 1 | 13 | 16 | |
| GSE43470 | ABCA12 | 26154 | 1 | 6 | 36 | |
| GSE46452 | ABCA12 | 26154 | 0 | 5 | 54 | |
| GSE47630 | ABCA12 | 26154 | 4 | 5 | 31 | |
| GSE54993 | ABCA12 | 26154 | 0 | 3 | 67 | |
| GSE54994 | ABCA12 | 26154 | 8 | 9 | 36 | |
| GSE60625 | ABCA12 | 26154 | 0 | 3 | 8 | |
| GSE74703 | ABCA12 | 26154 | 1 | 5 | 30 | |
| GSE74704 | ABCA12 | 26154 | 1 | 7 | 12 | |
| TCGA | ABCA12 | 26154 | 12 | 27 | 57 |
Total number of gains: 29; Total number of losses: 96; Total Number of normals: 363.
Somatic mutations of ABCA12:
Generating mutation plots.
Highly correlated genes for ABCA12:
Showing top 20/742 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCA12 | GINS4 | 0.761678 | 3 | 0 | 3 |
| ABCA12 | LRRC59 | 0.747105 | 4 | 0 | 4 |
| ABCA12 | FBXO45 | 0.725183 | 3 | 0 | 3 |
| ABCA12 | SPNS1 | 0.716273 | 4 | 0 | 4 |
| ABCA12 | MRPL30 | 0.691515 | 3 | 0 | 3 |
| ABCA12 | AEBP2 | 0.690895 | 3 | 0 | 3 |
| ABCA12 | SYT7 | 0.687921 | 4 | 0 | 4 |
| ABCA12 | SYCP2 | 0.687555 | 3 | 0 | 3 |
| ABCA12 | CPSF3 | 0.686584 | 6 | 0 | 5 |
| ABCA12 | WFDC5 | 0.684999 | 6 | 0 | 5 |
| ABCA12 | COMMD2 | 0.684301 | 4 | 0 | 4 |
| ABCA12 | ALG10 | 0.683935 | 4 | 0 | 4 |
| ABCA12 | UHRF1BP1 | 0.682693 | 3 | 0 | 3 |
| ABCA12 | TMEM167A | 0.672198 | 3 | 0 | 3 |
| ABCA12 | CDCA2 | 0.666669 | 4 | 0 | 3 |
| ABCA12 | SESN3 | 0.66502 | 3 | 0 | 3 |
| ABCA12 | C8orf76 | 0.664822 | 4 | 0 | 4 |
| ABCA12 | LACTB2 | 0.664138 | 3 | 0 | 3 |
| ABCA12 | NFE2L3 | 0.663909 | 4 | 0 | 3 |
| ABCA12 | S100A7A | 0.662754 | 5 | 0 | 4 |
For details and further investigation, click here
