| Full name: ELOVL fatty acid elongase 2 | Alias Symbol: Ssc2 | ||
| Type: protein-coding gene | Cytoband: 6p24.2 | ||
| Entrez ID: 54898 | HGNC ID: HGNC:14416 | Ensembl Gene: ENSG00000197977 | OMIM ID: 611814 |
| Drug and gene relationship at DGIdb | |||
Expression of ELOVL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELOVL2 | 54898 | 213712_at | 1.0138 | 0.1576 | |
| GSE20347 | ELOVL2 | 54898 | 213712_at | 0.2280 | 0.1106 | |
| GSE23400 | ELOVL2 | 54898 | 220029_at | 0.0132 | 0.8047 | |
| GSE26886 | ELOVL2 | 54898 | 220029_at | 0.0401 | 0.7446 | |
| GSE29001 | ELOVL2 | 54898 | 213712_at | 0.7837 | 0.1388 | |
| GSE38129 | ELOVL2 | 54898 | 213712_at | 0.3057 | 0.1285 | |
| GSE45670 | ELOVL2 | 54898 | 213712_at | -0.1020 | 0.6531 | |
| GSE53622 | ELOVL2 | 54898 | 32849 | 0.1987 | 0.1569 | |
| GSE53624 | ELOVL2 | 54898 | 32849 | 0.9702 | 0.0000 | |
| GSE63941 | ELOVL2 | 54898 | 220029_at | 0.0803 | 0.8934 | |
| GSE77861 | ELOVL2 | 54898 | 220029_at | -0.0808 | 0.3691 | |
| SRP133303 | ELOVL2 | 54898 | RNAseq | 0.9271 | 0.0083 | |
| SRP159526 | ELOVL2 | 54898 | RNAseq | 3.1166 | 0.0000 | |
| SRP219564 | ELOVL2 | 54898 | RNAseq | 2.3344 | 0.0118 | |
| TCGA | ELOVL2 | 54898 | RNAseq | 0.7465 | 0.0280 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ELOVL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELOVL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELOVL2 | 54898 | 4 | 7 | 19 | |
| GSE20123 | ELOVL2 | 54898 | 4 | 7 | 19 | |
| GSE43470 | ELOVL2 | 54898 | 8 | 2 | 33 | |
| GSE46452 | ELOVL2 | 54898 | 1 | 10 | 48 | |
| GSE47630 | ELOVL2 | 54898 | 7 | 8 | 25 | |
| GSE54993 | ELOVL2 | 54898 | 1 | 1 | 68 | |
| GSE54994 | ELOVL2 | 54898 | 10 | 3 | 40 | |
| GSE60625 | ELOVL2 | 54898 | 0 | 1 | 10 | |
| GSE74703 | ELOVL2 | 54898 | 7 | 2 | 27 | |
| GSE74704 | ELOVL2 | 54898 | 2 | 3 | 15 | |
| TCGA | ELOVL2 | 54898 | 15 | 28 | 53 |
Total number of gains: 59; Total number of losses: 72; Total Number of normals: 357.
Somatic mutations of ELOVL2:
Generating mutation plots.
Highly correlated genes for ELOVL2:
Showing top 20/40 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELOVL2 | PPP5C | 0.639166 | 3 | 0 | 3 |
| ELOVL2 | CHAT | 0.634536 | 4 | 0 | 4 |
| ELOVL2 | TGIF2 | 0.618895 | 4 | 0 | 3 |
| ELOVL2 | SEPHS1 | 0.616185 | 6 | 0 | 5 |
| ELOVL2 | SYN2 | 0.609277 | 6 | 0 | 6 |
| ELOVL2 | LRP3 | 0.606769 | 5 | 0 | 5 |
| ELOVL2 | MARCKSL1 | 0.604358 | 4 | 0 | 3 |
| ELOVL2 | SIX3 | 0.596471 | 4 | 0 | 3 |
| ELOVL2 | NOL4 | 0.595098 | 3 | 0 | 3 |
| ELOVL2 | RIPPLY3 | 0.5944 | 5 | 0 | 4 |
| ELOVL2 | MTMR4 | 0.592709 | 5 | 0 | 4 |
| ELOVL2 | CCP110 | 0.59255 | 4 | 0 | 3 |
| ELOVL2 | MCM3 | 0.586349 | 5 | 0 | 4 |
| ELOVL2 | UGT2B28 | 0.581797 | 3 | 0 | 3 |
| ELOVL2 | SOX30 | 0.578788 | 4 | 0 | 3 |
| ELOVL2 | TRRAP | 0.576851 | 4 | 0 | 3 |
| ELOVL2 | COL8A2 | 0.565656 | 5 | 0 | 3 |
| ELOVL2 | BEX1 | 0.561422 | 6 | 0 | 4 |
| ELOVL2 | KIF1A | 0.559707 | 5 | 0 | 3 |
| ELOVL2 | NPTX2 | 0.55207 | 5 | 0 | 3 |
For details and further investigation, click here
