| Full name: fibrosin | Alias Symbol: FBS|FLJ11618 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 64319 | HGNC ID: HGNC:20442 | Ensembl Gene: ENSG00000156860 | OMIM ID: 608601 |
| Drug and gene relationship at DGIdb | |||
Expression of FBRS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBRS | 64319 | 218255_s_at | -0.0018 | 0.9971 | |
| GSE20347 | FBRS | 64319 | 218255_s_at | -0.3330 | 0.0002 | |
| GSE23400 | FBRS | 64319 | 218255_s_at | -0.2938 | 0.0000 | |
| GSE26886 | FBRS | 64319 | 218255_s_at | 0.1348 | 0.4196 | |
| GSE29001 | FBRS | 64319 | 218255_s_at | -0.5798 | 0.0057 | |
| GSE38129 | FBRS | 64319 | 218255_s_at | -0.3361 | 0.0000 | |
| GSE45670 | FBRS | 64319 | 218255_s_at | -0.0976 | 0.3043 | |
| GSE53622 | FBRS | 64319 | 86600 | -0.2726 | 0.0000 | |
| GSE53624 | FBRS | 64319 | 35632 | -0.4848 | 0.0000 | |
| GSE63941 | FBRS | 64319 | 218255_s_at | 0.2099 | 0.3237 | |
| GSE77861 | FBRS | 64319 | 218255_s_at | -0.2011 | 0.3084 | |
| GSE97050 | FBRS | 64319 | A_33_P3334248 | 0.0927 | 0.7438 | |
| SRP007169 | FBRS | 64319 | RNAseq | -0.9192 | 0.0175 | |
| SRP008496 | FBRS | 64319 | RNAseq | -1.2260 | 0.0000 | |
| SRP064894 | FBRS | 64319 | RNAseq | -0.3817 | 0.0274 | |
| SRP133303 | FBRS | 64319 | RNAseq | -0.2751 | 0.0633 | |
| SRP159526 | FBRS | 64319 | RNAseq | -0.2754 | 0.3726 | |
| SRP193095 | FBRS | 64319 | RNAseq | -0.2966 | 0.0606 | |
| SRP219564 | FBRS | 64319 | RNAseq | -0.4944 | 0.0300 | |
| TCGA | FBRS | 64319 | RNAseq | 0.0114 | 0.7982 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FBRS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBRS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBRS | 64319 | 5 | 5 | 20 | |
| GSE20123 | FBRS | 64319 | 5 | 4 | 21 | |
| GSE43470 | FBRS | 64319 | 3 | 3 | 37 | |
| GSE46452 | FBRS | 64319 | 38 | 1 | 20 | |
| GSE47630 | FBRS | 64319 | 11 | 7 | 22 | |
| GSE54993 | FBRS | 64319 | 2 | 5 | 63 | |
| GSE54994 | FBRS | 64319 | 5 | 9 | 39 | |
| GSE60625 | FBRS | 64319 | 4 | 0 | 7 | |
| GSE74703 | FBRS | 64319 | 3 | 2 | 31 | |
| GSE74704 | FBRS | 64319 | 3 | 2 | 15 | |
| TCGA | FBRS | 64319 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of FBRS:
Generating mutation plots.
Highly correlated genes for FBRS:
Showing top 20/1014 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBRS | SH3BP2 | 0.739131 | 3 | 0 | 3 |
| FBRS | DDI2 | 0.72126 | 3 | 0 | 3 |
| FBRS | BCKDK | 0.719511 | 3 | 0 | 3 |
| FBRS | CHCHD5 | 0.711729 | 4 | 0 | 3 |
| FBRS | SYN3 | 0.706958 | 3 | 0 | 3 |
| FBRS | RNF207 | 0.703483 | 3 | 0 | 3 |
| FBRS | PLEKHM1 | 0.699417 | 9 | 0 | 9 |
| FBRS | SLC25A10 | 0.698677 | 5 | 0 | 4 |
| FBRS | TOM1 | 0.692057 | 10 | 0 | 10 |
| FBRS | ZACN | 0.688618 | 4 | 0 | 3 |
| FBRS | COPE | 0.68859 | 4 | 0 | 3 |
| FBRS | CLCC1 | 0.683935 | 3 | 0 | 3 |
| FBRS | RARG | 0.683452 | 9 | 0 | 9 |
| FBRS | KLF16 | 0.678829 | 4 | 0 | 3 |
| FBRS | SH3GL1 | 0.675688 | 10 | 0 | 9 |
| FBRS | DAZAP1 | 0.671952 | 3 | 0 | 3 |
| FBRS | SRGAP3 | 0.671728 | 3 | 0 | 3 |
| FBRS | AP1B1 | 0.671591 | 8 | 0 | 8 |
| FBRS | MAPK3 | 0.671495 | 9 | 0 | 8 |
| FBRS | TYRO3 | 0.67143 | 8 | 0 | 8 |
For details and further investigation, click here
