| Full name: TBC1 domain family member 10A | Alias Symbol: EPI64|AC004997.C22.2 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 83874 | HGNC ID: HGNC:23609 | Ensembl Gene: ENSG00000099992 | OMIM ID: 610020 |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D10A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D10A | 83874 | 226133_s_at | -0.4407 | 0.1880 | |
| GSE26886 | TBC1D10A | 83874 | 226133_s_at | -0.0779 | 0.7517 | |
| GSE45670 | TBC1D10A | 83874 | 226133_s_at | -0.1306 | 0.2597 | |
| GSE53622 | TBC1D10A | 83874 | 36235 | -0.6671 | 0.0000 | |
| GSE53624 | TBC1D10A | 83874 | 36235 | -0.8073 | 0.0000 | |
| GSE63941 | TBC1D10A | 83874 | 226133_s_at | 0.1984 | 0.5899 | |
| GSE77861 | TBC1D10A | 83874 | 226133_s_at | 0.0205 | 0.9050 | |
| GSE97050 | TBC1D10A | 83874 | A_23_P166421 | -0.0751 | 0.8346 | |
| SRP007169 | TBC1D10A | 83874 | RNAseq | -1.9707 | 0.0000 | |
| SRP008496 | TBC1D10A | 83874 | RNAseq | -1.8241 | 0.0000 | |
| SRP064894 | TBC1D10A | 83874 | RNAseq | -0.5112 | 0.0072 | |
| SRP133303 | TBC1D10A | 83874 | RNAseq | -0.6880 | 0.0002 | |
| SRP159526 | TBC1D10A | 83874 | RNAseq | -1.1938 | 0.0000 | |
| SRP193095 | TBC1D10A | 83874 | RNAseq | -0.4766 | 0.0007 | |
| SRP219564 | TBC1D10A | 83874 | RNAseq | -0.2926 | 0.5448 | |
| TCGA | TBC1D10A | 83874 | RNAseq | 0.0547 | 0.4222 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TBC1D10A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D10A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D10A | 83874 | 5 | 5 | 20 | |
| GSE20123 | TBC1D10A | 83874 | 5 | 4 | 21 | |
| GSE43470 | TBC1D10A | 83874 | 4 | 6 | 33 | |
| GSE46452 | TBC1D10A | 83874 | 31 | 1 | 27 | |
| GSE47630 | TBC1D10A | 83874 | 8 | 5 | 27 | |
| GSE54993 | TBC1D10A | 83874 | 3 | 6 | 61 | |
| GSE54994 | TBC1D10A | 83874 | 11 | 8 | 34 | |
| GSE60625 | TBC1D10A | 83874 | 5 | 0 | 6 | |
| GSE74703 | TBC1D10A | 83874 | 4 | 5 | 27 | |
| GSE74704 | TBC1D10A | 83874 | 2 | 1 | 17 | |
| TCGA | TBC1D10A | 83874 | 27 | 15 | 54 |
Total number of gains: 105; Total number of losses: 56; Total Number of normals: 327.
Somatic mutations of TBC1D10A:
Generating mutation plots.
Highly correlated genes for TBC1D10A:
Showing top 20/306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D10A | SMAGP | 0.764 | 3 | 0 | 3 |
| TBC1D10A | C15orf48 | 0.733417 | 3 | 0 | 3 |
| TBC1D10A | EPHA1 | 0.729915 | 3 | 0 | 3 |
| TBC1D10A | ESPL1 | 0.724595 | 3 | 0 | 3 |
| TBC1D10A | ATP6V1F | 0.719164 | 3 | 0 | 3 |
| TBC1D10A | CYP2J2 | 0.717473 | 3 | 0 | 3 |
| TBC1D10A | MAPK13 | 0.716731 | 3 | 0 | 3 |
| TBC1D10A | ETHE1 | 0.707739 | 3 | 0 | 3 |
| TBC1D10A | CYP11A1 | 0.701913 | 4 | 0 | 4 |
| TBC1D10A | ASCC2 | 0.694199 | 3 | 0 | 3 |
| TBC1D10A | C6orf132 | 0.689358 | 3 | 0 | 3 |
| TBC1D10A | LMO7 | 0.686847 | 3 | 0 | 3 |
| TBC1D10A | KRT32 | 0.686434 | 5 | 0 | 5 |
| TBC1D10A | VSIG10L | 0.685633 | 4 | 0 | 4 |
| TBC1D10A | UPK3B | 0.684828 | 3 | 0 | 3 |
| TBC1D10A | LGALS3 | 0.684552 | 3 | 0 | 3 |
| TBC1D10A | CXCR2 | 0.684306 | 3 | 0 | 3 |
| TBC1D10A | NEBL | 0.683817 | 3 | 0 | 3 |
| TBC1D10A | BLVRB | 0.683233 | 4 | 0 | 4 |
| TBC1D10A | PELI1 | 0.680866 | 3 | 0 | 3 |
For details and further investigation, click here
