| Full name: ETHE1 persulfide dioxygenase | Alias Symbol: YF13H12|HSCO | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 23474 | HGNC ID: HGNC:23287 | Ensembl Gene: ENSG00000105755 | OMIM ID: 608451 |
| Drug and gene relationship at DGIdb | |||
Expression of ETHE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETHE1 | 23474 | 204034_at | -0.8918 | 0.1645 | |
| GSE20347 | ETHE1 | 23474 | 204034_at | -1.6122 | 0.0000 | |
| GSE23400 | ETHE1 | 23474 | 204034_at | -1.1571 | 0.0000 | |
| GSE26886 | ETHE1 | 23474 | 204034_at | -1.2345 | 0.0000 | |
| GSE29001 | ETHE1 | 23474 | 204034_at | -1.7383 | 0.0001 | |
| GSE38129 | ETHE1 | 23474 | 204034_at | -1.1941 | 0.0000 | |
| GSE45670 | ETHE1 | 23474 | 204034_at | -0.3465 | 0.2088 | |
| GSE53622 | ETHE1 | 23474 | 82850 | -1.0312 | 0.0000 | |
| GSE53624 | ETHE1 | 23474 | 82850 | -1.5376 | 0.0000 | |
| GSE63941 | ETHE1 | 23474 | 204034_at | -0.3025 | 0.6605 | |
| GSE77861 | ETHE1 | 23474 | 204034_at | -0.9165 | 0.0411 | |
| GSE97050 | ETHE1 | 23474 | A_23_P142294 | -0.2993 | 0.4642 | |
| SRP007169 | ETHE1 | 23474 | RNAseq | -2.8593 | 0.0000 | |
| SRP008496 | ETHE1 | 23474 | RNAseq | -3.1378 | 0.0000 | |
| SRP064894 | ETHE1 | 23474 | RNAseq | -1.0865 | 0.0004 | |
| SRP133303 | ETHE1 | 23474 | RNAseq | -0.8066 | 0.0024 | |
| SRP159526 | ETHE1 | 23474 | RNAseq | -1.9018 | 0.0000 | |
| SRP193095 | ETHE1 | 23474 | RNAseq | -1.3710 | 0.0000 | |
| SRP219564 | ETHE1 | 23474 | RNAseq | -1.1710 | 0.0046 | |
| TCGA | ETHE1 | 23474 | RNAseq | -0.0866 | 0.3665 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by ETHE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETHE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETHE1 | 23474 | 6 | 5 | 19 | |
| GSE20123 | ETHE1 | 23474 | 5 | 4 | 21 | |
| GSE43470 | ETHE1 | 23474 | 4 | 11 | 28 | |
| GSE46452 | ETHE1 | 23474 | 45 | 1 | 13 | |
| GSE47630 | ETHE1 | 23474 | 8 | 6 | 26 | |
| GSE54993 | ETHE1 | 23474 | 17 | 4 | 49 | |
| GSE54994 | ETHE1 | 23474 | 6 | 12 | 35 | |
| GSE60625 | ETHE1 | 23474 | 9 | 0 | 2 | |
| GSE74703 | ETHE1 | 23474 | 4 | 7 | 25 | |
| GSE74704 | ETHE1 | 23474 | 4 | 2 | 14 | |
| TCGA | ETHE1 | 23474 | 14 | 15 | 67 |
Total number of gains: 122; Total number of losses: 67; Total Number of normals: 299.
Somatic mutations of ETHE1:
Generating mutation plots.
Highly correlated genes for ETHE1:
Showing top 20/907 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETHE1 | HES5 | 0.822218 | 3 | 0 | 3 |
| ETHE1 | FAM163B | 0.806669 | 3 | 0 | 3 |
| ETHE1 | TP53I3 | 0.803527 | 10 | 0 | 10 |
| ETHE1 | MUC22 | 0.796468 | 3 | 0 | 3 |
| ETHE1 | GPR78 | 0.784559 | 3 | 0 | 3 |
| ETHE1 | NCR1 | 0.777366 | 3 | 0 | 3 |
| ETHE1 | ECM1 | 0.769097 | 11 | 0 | 11 |
| ETHE1 | PTK6 | 0.768608 | 11 | 0 | 11 |
| ETHE1 | PHACTR4 | 0.768221 | 10 | 0 | 10 |
| ETHE1 | NCCRP1 | 0.767003 | 3 | 0 | 3 |
| ETHE1 | TRIP10 | 0.765017 | 10 | 0 | 10 |
| ETHE1 | EPS8L2 | 0.764284 | 11 | 0 | 11 |
| ETHE1 | SMAGP | 0.763118 | 11 | 0 | 11 |
| ETHE1 | SH3GL1 | 0.762791 | 10 | 0 | 10 |
| ETHE1 | KMT2D | 0.762639 | 3 | 0 | 3 |
| ETHE1 | EHD3 | 0.761492 | 10 | 0 | 10 |
| ETHE1 | PRSS27 | 0.761214 | 7 | 0 | 7 |
| ETHE1 | TTC9 | 0.759122 | 10 | 0 | 10 |
| ETHE1 | MAL | 0.75838 | 10 | 0 | 10 |
| ETHE1 | FBXL16 | 0.756081 | 5 | 0 | 5 |
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