| Full name: TBC1 domain family member 28 | Alias Symbol: FLJ40244 | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 254272 | HGNC ID: HGNC:26858 | Ensembl Gene: ENSG00000189375 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D28 | 254272 | 233462_at | -0.1090 | 0.7045 | |
| GSE26886 | TBC1D28 | 254272 | 233462_at | 0.2946 | 0.0037 | |
| GSE45670 | TBC1D28 | 254272 | 233462_at | -0.0856 | 0.2625 | |
| GSE63941 | TBC1D28 | 254272 | 233462_at | -0.2968 | 0.0601 | |
| GSE77861 | TBC1D28 | 254272 | 233462_at | 0.0045 | 0.9706 | |
| GSE97050 | TBC1D28 | 254272 | A_33_P3235880 | -0.2923 | 0.1834 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBC1D28 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D28 | 254272 | 3 | 3 | 24 | |
| GSE20123 | TBC1D28 | 254272 | 3 | 4 | 23 | |
| GSE43470 | TBC1D28 | 254272 | 1 | 5 | 37 | |
| GSE46452 | TBC1D28 | 254272 | 34 | 1 | 24 | |
| GSE47630 | TBC1D28 | 254272 | 7 | 1 | 32 | |
| GSE54993 | TBC1D28 | 254272 | 3 | 3 | 64 | |
| GSE54994 | TBC1D28 | 254272 | 6 | 6 | 41 | |
| GSE60625 | TBC1D28 | 254272 | 4 | 0 | 7 | |
| GSE74703 | TBC1D28 | 254272 | 1 | 2 | 33 | |
| GSE74704 | TBC1D28 | 254272 | 2 | 1 | 17 | |
| TCGA | TBC1D28 | 254272 | 19 | 23 | 54 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of TBC1D28:
Generating mutation plots.
Highly correlated genes for TBC1D28:
Showing top 20/152 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D28 | GFRA1 | 0.754264 | 3 | 0 | 3 |
| TBC1D28 | WHAMM | 0.753848 | 3 | 0 | 3 |
| TBC1D28 | NBR1 | 0.743373 | 3 | 0 | 3 |
| TBC1D28 | LRFN5 | 0.741315 | 3 | 0 | 3 |
| TBC1D28 | XRCC1 | 0.739684 | 3 | 0 | 3 |
| TBC1D28 | PDGFC | 0.735712 | 3 | 0 | 3 |
| TBC1D28 | CLMP | 0.720151 | 3 | 0 | 3 |
| TBC1D28 | EVI5 | 0.707401 | 3 | 0 | 3 |
| TBC1D28 | MAP4 | 0.703644 | 3 | 0 | 3 |
| TBC1D28 | ZNF787 | 0.703437 | 3 | 0 | 3 |
| TBC1D28 | KCND3 | 0.702857 | 3 | 0 | 3 |
| TBC1D28 | IL6 | 0.700281 | 3 | 0 | 3 |
| TBC1D28 | MAPK9 | 0.700278 | 3 | 0 | 3 |
| TBC1D28 | FTO | 0.699299 | 3 | 0 | 3 |
| TBC1D28 | EEF1D | 0.698431 | 3 | 0 | 3 |
| TBC1D28 | PXK | 0.697293 | 3 | 0 | 3 |
| TBC1D28 | DDX27 | 0.696338 | 3 | 0 | 3 |
| TBC1D28 | DPY19L2 | 0.691561 | 3 | 0 | 3 |
| TBC1D28 | CDC42EP3 | 0.689867 | 3 | 0 | 3 |
| TBC1D28 | EIF3G | 0.68355 | 3 | 0 | 3 |
For details and further investigation, click here
