| Full name: heme oxygenase 2 | Alias Symbol: HO-2 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 3163 | HGNC ID: HGNC:5014 | Ensembl Gene: ENSG00000103415 | OMIM ID: 141251 |
| Drug and gene relationship at DGIdb | |||
Expression of HMOX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HMOX2 | 3163 | 218120_s_at | -0.0786 | 0.9471 | |
| GSE20347 | HMOX2 | 3163 | 218120_s_at | -0.7869 | 0.0001 | |
| GSE23400 | HMOX2 | 3163 | 218120_s_at | -0.6225 | 0.0000 | |
| GSE26886 | HMOX2 | 3163 | 218120_s_at | -0.8226 | 0.0006 | |
| GSE29001 | HMOX2 | 3163 | 218121_at | -0.4412 | 0.0448 | |
| GSE38129 | HMOX2 | 3163 | 218120_s_at | -0.4574 | 0.0222 | |
| GSE45670 | HMOX2 | 3163 | 218120_s_at | -0.2245 | 0.2896 | |
| GSE53622 | HMOX2 | 3163 | 43594 | -0.6281 | 0.0000 | |
| GSE53624 | HMOX2 | 3163 | 43594 | -1.0513 | 0.0000 | |
| GSE63941 | HMOX2 | 3163 | 218120_s_at | 1.0391 | 0.0190 | |
| GSE77861 | HMOX2 | 3163 | 218120_s_at | -0.1783 | 0.6412 | |
| GSE97050 | HMOX2 | 3163 | A_23_P100501 | 0.1223 | 0.8545 | |
| SRP007169 | HMOX2 | 3163 | RNAseq | -1.9821 | 0.0001 | |
| SRP008496 | HMOX2 | 3163 | RNAseq | -1.9772 | 0.0000 | |
| SRP064894 | HMOX2 | 3163 | RNAseq | -1.0107 | 0.0000 | |
| SRP133303 | HMOX2 | 3163 | RNAseq | -0.2952 | 0.0740 | |
| SRP159526 | HMOX2 | 3163 | RNAseq | -0.7860 | 0.0263 | |
| SRP193095 | HMOX2 | 3163 | RNAseq | -0.5212 | 0.0033 | |
| SRP219564 | HMOX2 | 3163 | RNAseq | -0.9531 | 0.0218 | |
| TCGA | HMOX2 | 3163 | RNAseq | -0.1954 | 0.0081 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by HMOX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HMOX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HMOX2 | 3163 | 5 | 5 | 20 | |
| GSE20123 | HMOX2 | 3163 | 5 | 4 | 21 | |
| GSE43470 | HMOX2 | 3163 | 5 | 6 | 32 | |
| GSE46452 | HMOX2 | 3163 | 38 | 1 | 20 | |
| GSE47630 | HMOX2 | 3163 | 13 | 6 | 21 | |
| GSE54993 | HMOX2 | 3163 | 3 | 5 | 62 | |
| GSE54994 | HMOX2 | 3163 | 5 | 9 | 39 | |
| GSE60625 | HMOX2 | 3163 | 4 | 0 | 7 | |
| GSE74703 | HMOX2 | 3163 | 5 | 4 | 27 | |
| GSE74704 | HMOX2 | 3163 | 3 | 2 | 15 | |
| TCGA | HMOX2 | 3163 | 19 | 13 | 64 |
Total number of gains: 105; Total number of losses: 55; Total Number of normals: 328.
Somatic mutations of HMOX2:
Generating mutation plots.
Highly correlated genes for HMOX2:
Showing top 20/1084 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HMOX2 | NUAK2 | 0.741787 | 3 | 0 | 3 |
| HMOX2 | EPGN | 0.739143 | 3 | 0 | 3 |
| HMOX2 | ORMDL2 | 0.735745 | 8 | 0 | 8 |
| HMOX2 | NIPAL1 | 0.726909 | 3 | 0 | 3 |
| HMOX2 | RTN4IP1 | 0.725318 | 3 | 0 | 3 |
| HMOX2 | ELOVL1 | 0.717458 | 4 | 0 | 3 |
| HMOX2 | ARNTL2 | 0.7068 | 11 | 0 | 11 |
| HMOX2 | CDA | 0.705626 | 10 | 0 | 10 |
| HMOX2 | CERS3 | 0.697327 | 6 | 0 | 6 |
| HMOX2 | SDR9C7 | 0.696623 | 6 | 0 | 6 |
| HMOX2 | TOLLIP | 0.693696 | 10 | 0 | 10 |
| HMOX2 | SH3GL1 | 0.691704 | 11 | 0 | 9 |
| HMOX2 | P2RX3 | 0.690641 | 3 | 0 | 3 |
| HMOX2 | STRN | 0.690129 | 8 | 0 | 8 |
| HMOX2 | GALE | 0.689637 | 10 | 0 | 9 |
| HMOX2 | TBC1D2 | 0.689539 | 5 | 0 | 5 |
| HMOX2 | APOBEC1 | 0.684047 | 4 | 0 | 4 |
| HMOX2 | PLIN3 | 0.683147 | 11 | 0 | 10 |
| HMOX2 | CRCT1 | 0.682249 | 10 | 0 | 10 |
| HMOX2 | TBL3 | 0.680722 | 9 | 0 | 8 |
For details and further investigation, click here
