| Full name: tudor domain containing 6 | Alias Symbol: NY-CO-45|bA446F17.4|CT41.2|SPATA36 | ||
| Type: protein-coding gene | Cytoband: 6p12.3 | ||
| Entrez ID: 221400 | HGNC ID: HGNC:21339 | Ensembl Gene: ENSG00000180113 | OMIM ID: 611200 |
| Drug and gene relationship at DGIdb | |||
Expression of TDRD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TDRD6 | 221400 | 232692_at | 0.2488 | 0.7131 | |
| GSE26886 | TDRD6 | 221400 | 232692_at | 0.1193 | 0.5816 | |
| GSE45670 | TDRD6 | 221400 | 232692_at | -0.5748 | 0.0830 | |
| GSE53622 | TDRD6 | 221400 | 61421 | 1.5601 | 0.0000 | |
| GSE53624 | TDRD6 | 221400 | 44436 | 0.1679 | 0.1418 | |
| GSE63941 | TDRD6 | 221400 | 232692_at | -2.0652 | 0.0000 | |
| GSE77861 | TDRD6 | 221400 | 232692_at | 0.0558 | 0.6527 | |
| GSE97050 | TDRD6 | 221400 | A_33_P3232965 | 0.2900 | 0.3166 | |
| SRP007169 | TDRD6 | 221400 | RNAseq | 2.3338 | 0.0107 | |
| SRP064894 | TDRD6 | 221400 | RNAseq | 0.3168 | 0.3716 | |
| SRP133303 | TDRD6 | 221400 | RNAseq | 1.1170 | 0.0000 | |
| SRP159526 | TDRD6 | 221400 | RNAseq | 0.4801 | 0.4382 | |
| SRP193095 | TDRD6 | 221400 | RNAseq | 0.7117 | 0.0002 | |
| SRP219564 | TDRD6 | 221400 | RNAseq | 0.8988 | 0.0484 | |
| TCGA | TDRD6 | 221400 | RNAseq | -0.2630 | 0.3929 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by TDRD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TDRD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TDRD6 | 221400 | 6 | 2 | 22 | |
| GSE20123 | TDRD6 | 221400 | 6 | 2 | 22 | |
| GSE43470 | TDRD6 | 221400 | 5 | 0 | 38 | |
| GSE46452 | TDRD6 | 221400 | 2 | 10 | 47 | |
| GSE47630 | TDRD6 | 221400 | 7 | 5 | 28 | |
| GSE54993 | TDRD6 | 221400 | 3 | 1 | 66 | |
| GSE54994 | TDRD6 | 221400 | 8 | 3 | 42 | |
| GSE60625 | TDRD6 | 221400 | 0 | 3 | 8 | |
| GSE74703 | TDRD6 | 221400 | 5 | 0 | 31 | |
| GSE74704 | TDRD6 | 221400 | 2 | 1 | 17 | |
| TCGA | TDRD6 | 221400 | 18 | 14 | 64 |
Total number of gains: 62; Total number of losses: 41; Total Number of normals: 385.
Somatic mutations of TDRD6:
Generating mutation plots.
Highly correlated genes for TDRD6:
Showing top 20/65 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TDRD6 | BTBD18 | 0.709161 | 3 | 0 | 3 |
| TDRD6 | TMEM119 | 0.68072 | 4 | 0 | 3 |
| TDRD6 | NOX4 | 0.661286 | 3 | 0 | 3 |
| TDRD6 | HEXB | 0.657501 | 3 | 0 | 3 |
| TDRD6 | THBS2 | 0.647371 | 3 | 0 | 3 |
| TDRD6 | VCAN | 0.64367 | 3 | 0 | 3 |
| TDRD6 | GORASP2 | 0.641262 | 3 | 0 | 3 |
| TDRD6 | PHF1 | 0.640594 | 3 | 0 | 3 |
| TDRD6 | HTRA4 | 0.638283 | 4 | 0 | 3 |
| TDRD6 | GPX8 | 0.636396 | 3 | 0 | 3 |
| TDRD6 | TMEM263 | 0.636125 | 3 | 0 | 3 |
| TDRD6 | MXRA8 | 0.635518 | 3 | 0 | 3 |
| TDRD6 | SCG5 | 0.622776 | 4 | 0 | 3 |
| TDRD6 | DNAJC16 | 0.621531 | 3 | 0 | 3 |
| TDRD6 | INPP5F | 0.619977 | 4 | 0 | 3 |
| TDRD6 | CPXM1 | 0.613202 | 3 | 0 | 3 |
| TDRD6 | FANK1 | 0.610034 | 3 | 0 | 3 |
| TDRD6 | ARHGAP28 | 0.609383 | 3 | 0 | 3 |
| TDRD6 | SDSL | 0.608067 | 3 | 0 | 3 |
| TDRD6 | DACT1 | 0.605005 | 4 | 0 | 3 |
For details and further investigation, click here
