| Full name: inositol polyphosphate-5-phosphatase F | Alias Symbol: SAC2|KIAA0966|hSac2 | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 22876 | HGNC ID: HGNC:17054 | Ensembl Gene: ENSG00000198825 | OMIM ID: 609389 |
| Drug and gene relationship at DGIdb | |||
Expression of INPP5F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INPP5F | 22876 | 203607_at | 0.2234 | 0.3743 | |
| GSE20347 | INPP5F | 22876 | 203607_at | 0.1731 | 0.2171 | |
| GSE23400 | INPP5F | 22876 | 203607_at | 0.2128 | 0.0025 | |
| GSE26886 | INPP5F | 22876 | 203607_at | 0.0908 | 0.6199 | |
| GSE29001 | INPP5F | 22876 | 203607_at | 0.2483 | 0.3092 | |
| GSE38129 | INPP5F | 22876 | 203607_at | 0.1989 | 0.1473 | |
| GSE45670 | INPP5F | 22876 | 203607_at | 0.0604 | 0.7504 | |
| GSE53622 | INPP5F | 22876 | 19413 | 0.1487 | 0.0677 | |
| GSE53624 | INPP5F | 22876 | 22545 | 0.3388 | 0.0000 | |
| GSE63941 | INPP5F | 22876 | 203607_at | -0.8861 | 0.0146 | |
| GSE77861 | INPP5F | 22876 | 203607_at | 0.3814 | 0.2485 | |
| GSE97050 | INPP5F | 22876 | A_33_P3238920 | 0.4238 | 0.2423 | |
| SRP007169 | INPP5F | 22876 | RNAseq | 1.4507 | 0.0005 | |
| SRP008496 | INPP5F | 22876 | RNAseq | 1.3757 | 0.0000 | |
| SRP064894 | INPP5F | 22876 | RNAseq | 0.0168 | 0.9196 | |
| SRP133303 | INPP5F | 22876 | RNAseq | 0.3923 | 0.0244 | |
| SRP159526 | INPP5F | 22876 | RNAseq | 0.0861 | 0.7272 | |
| SRP193095 | INPP5F | 22876 | RNAseq | 0.2624 | 0.0337 | |
| SRP219564 | INPP5F | 22876 | RNAseq | 0.1338 | 0.6395 | |
| TCGA | INPP5F | 22876 | RNAseq | 0.0609 | 0.3138 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by INPP5F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INPP5F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INPP5F | 22876 | 2 | 8 | 20 | |
| GSE20123 | INPP5F | 22876 | 2 | 8 | 20 | |
| GSE43470 | INPP5F | 22876 | 0 | 9 | 34 | |
| GSE46452 | INPP5F | 22876 | 0 | 11 | 48 | |
| GSE47630 | INPP5F | 22876 | 2 | 14 | 24 | |
| GSE54993 | INPP5F | 22876 | 8 | 0 | 62 | |
| GSE54994 | INPP5F | 22876 | 1 | 9 | 43 | |
| GSE60625 | INPP5F | 22876 | 0 | 0 | 11 | |
| GSE74703 | INPP5F | 22876 | 0 | 6 | 30 | |
| GSE74704 | INPP5F | 22876 | 1 | 3 | 16 | |
| TCGA | INPP5F | 22876 | 5 | 28 | 63 |
Total number of gains: 21; Total number of losses: 96; Total Number of normals: 371.
Somatic mutations of INPP5F:
Generating mutation plots.
Highly correlated genes for INPP5F:
Showing top 20/54 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INPP5F | CA9 | 0.701489 | 3 | 0 | 3 |
| INPP5F | STAT4 | 0.698569 | 3 | 0 | 3 |
| INPP5F | PTPRR | 0.691028 | 3 | 0 | 3 |
| INPP5F | ARAP3 | 0.657032 | 4 | 0 | 4 |
| INPP5F | MAGEL2 | 0.644867 | 3 | 0 | 3 |
| INPP5F | WDR74 | 0.639748 | 4 | 0 | 3 |
| INPP5F | ZBTB46 | 0.633455 | 3 | 0 | 3 |
| INPP5F | CADPS | 0.629062 | 3 | 0 | 3 |
| INPP5F | TDRD6 | 0.619977 | 4 | 0 | 3 |
| INPP5F | ORAI2 | 0.618884 | 4 | 0 | 3 |
| INPP5F | VAV2 | 0.617682 | 5 | 0 | 4 |
| INPP5F | IL12RB2 | 0.616718 | 5 | 0 | 3 |
| INPP5F | XRCC2 | 0.612783 | 3 | 0 | 3 |
| INPP5F | CXorf21 | 0.605725 | 4 | 0 | 3 |
| INPP5F | KLHL28 | 0.601109 | 4 | 0 | 3 |
| INPP5F | PPP1R18 | 0.59726 | 4 | 0 | 3 |
| INPP5F | FKBP14 | 0.591062 | 5 | 0 | 3 |
| INPP5F | MFAP2 | 0.589103 | 5 | 0 | 3 |
| INPP5F | NRIP3 | 0.58727 | 5 | 0 | 3 |
| INPP5F | GNLY | 0.586914 | 4 | 0 | 3 |
For details and further investigation, click here
