| Full name: serine dehydratase like | Alias Symbol: SDS-RS1|cSDH | ||
| Type: protein-coding gene | Cytoband: 12q24.13 | ||
| Entrez ID: 113675 | HGNC ID: HGNC:30404 | Ensembl Gene: ENSG00000139410 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SDSL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDSL | 113675 | 228274_at | 0.1713 | 0.7730 | |
| GSE26886 | SDSL | 113675 | 228274_at | 0.2135 | 0.3525 | |
| GSE45670 | SDSL | 113675 | 228274_at | 0.2943 | 0.1135 | |
| GSE53622 | SDSL | 113675 | 29529 | 0.3751 | 0.0018 | |
| GSE53624 | SDSL | 113675 | 29529 | 0.5609 | 0.0000 | |
| GSE63941 | SDSL | 113675 | 228274_at | -0.6548 | 0.2167 | |
| GSE77861 | SDSL | 113675 | 228274_at | -0.1211 | 0.3303 | |
| GSE97050 | SDSL | 113675 | A_33_P3227472 | 0.4428 | 0.2151 | |
| SRP064894 | SDSL | 113675 | RNAseq | 2.0792 | 0.0000 | |
| SRP133303 | SDSL | 113675 | RNAseq | 1.1797 | 0.0000 | |
| SRP159526 | SDSL | 113675 | RNAseq | 0.8815 | 0.1304 | |
| SRP193095 | SDSL | 113675 | RNAseq | -0.3036 | 0.2610 | |
| SRP219564 | SDSL | 113675 | RNAseq | 0.6572 | 0.4353 | |
| TCGA | SDSL | 113675 | RNAseq | -0.4286 | 0.0163 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SDSL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDSL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDSL | 113675 | 4 | 3 | 23 | |
| GSE20123 | SDSL | 113675 | 4 | 3 | 23 | |
| GSE43470 | SDSL | 113675 | 2 | 0 | 41 | |
| GSE46452 | SDSL | 113675 | 9 | 1 | 49 | |
| GSE47630 | SDSL | 113675 | 9 | 3 | 28 | |
| GSE54993 | SDSL | 113675 | 0 | 5 | 65 | |
| GSE54994 | SDSL | 113675 | 4 | 2 | 47 | |
| GSE60625 | SDSL | 113675 | 0 | 0 | 11 | |
| GSE74703 | SDSL | 113675 | 2 | 0 | 34 | |
| GSE74704 | SDSL | 113675 | 2 | 2 | 16 | |
| TCGA | SDSL | 113675 | 22 | 11 | 63 |
Total number of gains: 58; Total number of losses: 30; Total Number of normals: 400.
Somatic mutations of SDSL:
Generating mutation plots.
Highly correlated genes for SDSL:
Showing top 20/74 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDSL | C2 | 0.68909 | 4 | 0 | 4 |
| SDSL | BATF2 | 0.678111 | 5 | 0 | 4 |
| SDSL | GLB1 | 0.645757 | 3 | 0 | 3 |
| SDSL | SPATA13 | 0.628111 | 4 | 0 | 3 |
| SDSL | FAM78A | 0.620144 | 4 | 0 | 4 |
| SDSL | ADAMTS6 | 0.620004 | 3 | 0 | 3 |
| SDSL | PLA2G15 | 0.617265 | 4 | 0 | 3 |
| SDSL | CD300C | 0.615386 | 4 | 0 | 3 |
| SDSL | IL4I1 | 0.608124 | 6 | 0 | 4 |
| SDSL | GNLY | 0.608076 | 5 | 0 | 4 |
| SDSL | TDRD6 | 0.608067 | 3 | 0 | 3 |
| SDSL | KCNAB2 | 0.606814 | 3 | 0 | 3 |
| SDSL | TFEC | 0.60483 | 4 | 0 | 3 |
| SDSL | AKAP5 | 0.598183 | 5 | 0 | 4 |
| SDSL | ETV7 | 0.597998 | 5 | 0 | 4 |
| SDSL | MYO7A | 0.595063 | 4 | 0 | 3 |
| SDSL | SLAMF8 | 0.592276 | 6 | 0 | 5 |
| SDSL | IGFLR1 | 0.590821 | 6 | 0 | 4 |
| SDSL | ALDH16A1 | 0.58266 | 4 | 0 | 3 |
| SDSL | ACP2 | 0.580507 | 6 | 0 | 4 |
For details and further investigation, click here
