| Full name: secretogranin V | Alias Symbol: 7B2|SgV | ||
| Type: protein-coding gene | Cytoband: 15q13.3 | ||
| Entrez ID: 6447 | HGNC ID: HGNC:10816 | Ensembl Gene: ENSG00000166922 | OMIM ID: 173120 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SCG5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCG5 | 6447 | 203889_at | 0.6923 | 0.3225 | |
| GSE20347 | SCG5 | 6447 | 203889_at | 0.9271 | 0.0005 | |
| GSE23400 | SCG5 | 6447 | 203889_at | 0.4953 | 0.0000 | |
| GSE26886 | SCG5 | 6447 | 203889_at | 1.8550 | 0.0007 | |
| GSE29001 | SCG5 | 6447 | 203889_at | 1.7041 | 0.0004 | |
| GSE38129 | SCG5 | 6447 | 203889_at | 0.9519 | 0.0221 | |
| GSE45670 | SCG5 | 6447 | 203889_at | 1.2456 | 0.0166 | |
| GSE53622 | SCG5 | 6447 | 105326 | 1.3429 | 0.0000 | |
| GSE53624 | SCG5 | 6447 | 105326 | 1.9464 | 0.0000 | |
| GSE63941 | SCG5 | 6447 | 203889_at | -4.5761 | 0.0000 | |
| GSE77861 | SCG5 | 6447 | 203889_at | 0.1459 | 0.2515 | |
| GSE97050 | SCG5 | 6447 | A_23_P62081 | 0.0730 | 0.8204 | |
| SRP064894 | SCG5 | 6447 | RNAseq | 3.6146 | 0.0000 | |
| SRP133303 | SCG5 | 6447 | RNAseq | 2.8258 | 0.0000 | |
| SRP159526 | SCG5 | 6447 | RNAseq | 1.8552 | 0.0134 | |
| SRP219564 | SCG5 | 6447 | RNAseq | 1.3906 | 0.2323 | |
| TCGA | SCG5 | 6447 | RNAseq | -0.4677 | 0.1099 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by SCG5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCG5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCG5 | 6447 | 2 | 7 | 21 | |
| GSE20123 | SCG5 | 6447 | 2 | 7 | 21 | |
| GSE43470 | SCG5 | 6447 | 4 | 4 | 35 | |
| GSE46452 | SCG5 | 6447 | 3 | 7 | 49 | |
| GSE47630 | SCG5 | 6447 | 8 | 11 | 21 | |
| GSE54993 | SCG5 | 6447 | 4 | 6 | 60 | |
| GSE54994 | SCG5 | 6447 | 5 | 8 | 40 | |
| GSE60625 | SCG5 | 6447 | 4 | 0 | 7 | |
| GSE74703 | SCG5 | 6447 | 4 | 3 | 29 | |
| GSE74704 | SCG5 | 6447 | 1 | 6 | 13 | |
| TCGA | SCG5 | 6447 | 13 | 17 | 66 |
Total number of gains: 50; Total number of losses: 76; Total Number of normals: 362.
Somatic mutations of SCG5:
Generating mutation plots.
Highly correlated genes for SCG5:
Showing top 20/869 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCG5 | CALU | 0.735981 | 10 | 0 | 10 |
| SCG5 | LHFPL2 | 0.732501 | 11 | 0 | 11 |
| SCG5 | PXDN | 0.731762 | 11 | 0 | 11 |
| SCG5 | TMEM263 | 0.727733 | 7 | 0 | 7 |
| SCG5 | LRRN4CL | 0.714632 | 3 | 0 | 3 |
| SCG5 | FAP | 0.7137 | 10 | 0 | 8 |
| SCG5 | DACT1 | 0.712667 | 12 | 0 | 11 |
| SCG5 | VCAN | 0.711278 | 12 | 0 | 11 |
| SCG5 | RGS3 | 0.70319 | 10 | 0 | 10 |
| SCG5 | COL5A1 | 0.700978 | 12 | 0 | 12 |
| SCG5 | LOXL2 | 0.70028 | 11 | 0 | 11 |
| SCG5 | FNDC1 | 0.697638 | 7 | 0 | 6 |
| SCG5 | GALNT10 | 0.693562 | 10 | 0 | 10 |
| SCG5 | COL4A1 | 0.690858 | 11 | 0 | 10 |
| SCG5 | S1PR3 | 0.690438 | 3 | 0 | 3 |
| SCG5 | ADAMTS12 | 0.689197 | 7 | 0 | 6 |
| SCG5 | CSGALNACT2 | 0.687205 | 11 | 0 | 10 |
| SCG5 | COL4A2 | 0.687154 | 11 | 0 | 10 |
| SCG5 | RHOBTB1 | 0.686763 | 12 | 0 | 11 |
| SCG5 | COL12A1 | 0.685558 | 7 | 0 | 7 |
For details and further investigation, click here
